TWAS
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Usage
Models
Genes
Traits
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Traits
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Standing height
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chr3:71,726,259-73,191,526
Best TWAS P=1.57e-12 · Best GWAS P=1.89e-37 conditioned to 4.41e-30
71.8M
72M
72.2M
72.4M
72.6M
72.8M
73M
73.2M
0
10
20
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
NTR
Blood
RYBP
0.05
0.03
lasso
5
0.04
5.4e-14
-6.4
-7.1
1.6e-12
-0.25
1.00
0.00
TRUE
2
YFS
Blood
RYBP
0.25
0.16
enet
33
0.23
7.8e-75
5.0
-6.5
6.4e-11
-0.44
1.00
0.00
FALSE
3
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
RYBP
0.10
0.00
blup
62
0.04
5.4e-04
-5.0
-6.3
3.0e-10
-0.18
0.05
0.05
FALSE