Best TWAS P=1.57e-12 · Best GWAS P=1.89e-37 conditioned to 4.41e-30
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | RYBP | 0.05 | 0.03 | lasso | 5 | 0.04 | 5.4e-14 | -6.4 | -7.1 | 1.6e-12 | -0.25 | 1.00 | 0.00 | TRUE |
| 2 | YFS | Blood | RYBP | 0.25 | 0.16 | enet | 33 | 0.23 | 7.8e-75 | 5.0 | -6.5 | 6.4e-11 | -0.44 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | RYBP | 0.10 | 0.00 | blup | 62 | 0.04 | 5.4e-04 | -5.0 | -6.3 | 3.0e-10 | -0.18 | 0.05 | 0.05 | FALSE |