Best TWAS P=1.06e-08 · Best GWAS P=3.78e-12 conditioned to 0.000168
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | RP11-33B1.4 | 0.21 | 0.10 | lasso | 7 | 0.12 | 6.2e-09 | -4.3 | 5.7 | 1.5e-08 | -0.23 | 0.77 | 0.01 | TRUE |
| 2 | GTEx | Ovary | RP11-33B1.1 | 0.26 | 0.07 | enet | 33 | 0.16 | 1.2e-04 | 4.1 | 5.7 | 1.1e-08 | -0.41 | 0.27 | 0.08 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RP11-33B1.4 | 0.12 | 0.01 | lasso | 6 | 0.01 | 4.7e-02 | -4.3 | 5.4 | 7.2e-08 | -0.18 | 0.20 | 0.06 | FALSE |