[Hub]/) : Traits : Standing height :

chr4:121,982,122-124,538,705

Best TWAS P=3.23e-18 · Best GWAS P=2.12e-15 conditioned to 0.622

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BBS7 0.19 0.21 bslmm 423 0.23 1.8e-27 -7.9 -8.0 1.1e-15 0.93 0.00 1.00 FALSE
2 CommonMind Brain Pre-frontal Cortex TMEM155 0.06 0.05 lasso 3 0.02 5.5e-04 -6.5 -6.1 1.1e-09 0.68 0.12 0.82 FALSE
3 GTEx Adipose Subcutaneous EXOSC9 0.07 0.00 lasso 2 0.00 4.5e-01 -6.1 6.0 1.6e-09 -0.83 0.05 0.34 FALSE
4 GTEx Brain Cerebellar Hemisphere BBS7 0.27 0.05 lasso 3 0.08 4.7e-03 -6.0 -5.3 9.1e-08 0.61 0.08 0.34 FALSE
5 GTEx Brain Cerebellar Hemisphere NUDT6 0.32 0.07 enet 16 0.16 5.0e-05 -4.7 -5.2 2.0e-07 0.03 0.20 0.10 TRUE
6 GTEx Brain Cerebellum BBS7 0.20 -0.01 enet 24 0.01 2.2e-01 -6.0 -6.6 4.7e-11 0.73 0.07 0.73 FALSE
7 GTEx Breast Mammary Tissue NUDT6 0.25 0.10 lasso 3 0.08 4.2e-05 6.2 6.3 3.4e-10 0.01 0.05 0.93 FALSE
8 GTEx Breast Mammary Tissue (Male) NUDT6 0.29 0.00 lasso 6 0.00 3.5e-01 5.5 5.9 3.1e-09 0.04 0.03 0.50 FALSE
9 GTEx Breast Mammary Tissue (Female) NUDT6 0.30 -0.01 enet 30 0.00 2.6e-01 6.6 5.5 4.0e-08 -0.03 0.03 0.33 FALSE
10 GTEx Cells EBV-transformed lymphocytes EXOSC9 0.29 0.17 lasso 7 0.16 6.6e-06 7.2 7.9 2.9e-15 -0.68 0.17 0.81 FALSE
11 GTEx Cells Transformed fibroblasts BBS7 0.16 0.09 lasso 7 0.16 2.9e-12 -7.9 -8.5 1.5e-17 0.91 0.00 1.00 FALSE
12 GTEx Colon Transverse BBS12 0.12 0.05 enet 29 0.12 3.2e-06 -2.0 7.2 4.1e-13 -0.07 0.05 0.46 TRUE
13 GTEx Muscle Skeletal RP11-170N16.3 0.07 0.07 lasso 3 0.06 8.8e-07 4.8 5.3 8.6e-08 0.04 0.46 0.52 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic NUDT6 0.07 0.02 lasso 6 0.03 1.5e-02 4.5 5.4 5.7e-08 0.04 0.11 0.76 FALSE
15 GTEx Skin Sun Exposed Lower leg NUDT6 0.11 0.08 lasso 3 0.08 6.2e-07 5.5 5.5 3.5e-08 0.03 0.90 0.07 FALSE
16 GTEx Testis EXOSC9 0.17 0.07 lasso 8 0.10 2.5e-05 -6.0 7.8 4.1e-15 -0.87 0.01 0.98 FALSE
17 ROSMAP Brain Pre-frontal Cortex EXOSC9 0.05 0.02 lasso 7 0.02 5.3e-04 6.6 6.9 6.4e-12 -0.54 0.42 0.30 FALSE
18 YFS Blood EXOSC9 0.06 0.09 bslmm 401 0.09 7.0e-28 7.5 7.4 1.1e-13 -0.63 0.10 0.90 FALSE
19 The Cancer Genome Atlas Breast Invasive Carcinoma EXOSC9 0.03 0.04 enet 9 0.04 2.8e-08 6.9 8.1 5.4e-16 -0.70 0.35 0.65 FALSE
20 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CCNA2 0.11 -0.01 enet 14 0.02 4.4e-02 1.5 5.2 1.8e-07 -0.56 0.00 0.28 FALSE
21 The Cancer Genome Atlas Colon Adenocarcinoma BBS7 0.05 0.00 blup 47 0.02 1.9e-02 6.9 -6.9 3.8e-12 0.56 0.02 0.14 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BBS7 0.04 0.02 blup 47 0.03 1.3e-04 -6.0 -6.1 1.1e-09 0.91 0.05 0.91 FALSE
23 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCNA2 0.03 0.01 blup 34 0.02 1.5e-03 -7.9 8.7 3.2e-18 -0.80 0.00 0.97 TRUE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma BBS7 0.04 0.04 lasso 2 0.03 6.1e-04 -7.9 -7.9 3.2e-15 1.00 0.00 1.00 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FGF2 0.06 0.04 blup 65 0.05 4.4e-06 6.8 6.5 1.1e-10 -0.03 0.00 0.99 FALSE
26 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EXOSC9 0.03 0.02 lasso 2 0.02 1.0e-03 7.4 8.0 1.2e-15 -0.66 0.07 0.40 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma EXOSC9 0.04 0.05 lasso 2 0.04 7.1e-05 6.9 7.9 2.0e-15 -0.78 0.03 0.94 FALSE