[Hub]/) : Traits : Standing height : ← →

chr4:105,373,669-107,092,169

Best TWAS P=6.55e-42 · Best GWAS P=1.36e-49 conditioned to 2.49e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Esophagus Mucosa	PPA2	0.18	0.06	enet	14	0.12	2.5e-08	13.01	-13.6	6.6e-42	0.72	0.11	0.89	TRUE
8	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-14.18	-13.2	6.9e-40	0.88	0.02	0.96	TRUE
11	GTEx	Lung	PPA2	0.09	0.02	enet	16	0.03	1.4e-03	0.88	-6.0	1.8e-09	0.45	0.19	0.34	TRUE
4	GTEx	Artery Tibial	PPA2	0.08	0.02	enet	19	0.04	5.0e-04	-10.16	-5.2	2.0e-07	0.51	0.17	0.18	TRUE
14	GTEx	Ovary	PPA2	0.18	0.10	lasso	3	0.14	2.2e-04	-10.16	-12.0	3.2e-33	0.76	0.04	0.80	FALSE
6	GTEx	Brain Cortex	PPA2	0.14	0.09	lasso	9	0.09	1.6e-03	-11.81	-12.0	5.4e-33	0.88	0.04	0.74	FALSE
16	GTEx	Skin Sun Exposed Lower leg	TET2	0.09	0.01	enet	18	0.02	3.6e-03	-14.79	-11.5	1.6e-30	0.69	0.01	0.95	FALSE
7	GTEx	Cells Transformed fibroblasts	PPA2	0.11	0.03	lasso	3	0.01	6.5e-02	-8.92	-10.2	3.2e-24	0.67	0.39	0.16	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	PPA2	0.04	0.02	blup	84	0.04	6.1e-05	-11.28	-10.1	6.8e-24	0.77	0.14	0.65	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPA2	0.08	0.03	bslmm	429	0.04	2.2e-05	-9.75	-9.9	2.7e-23	0.66	0.08	0.89	FALSE
13	GTEx	Nerve Tibial	PPA2	0.13	0.07	enet	23	0.07	2.1e-05	-10.16	-9.8	7.3e-23	0.66	0.36	0.46	FALSE
3	GTEx	Artery Aorta	PPA2	0.11	-0.01	enet	24	0.01	1.6e-01	-14.18	-9.1	1.0e-19	0.63	0.06	0.46	FALSE
5	GTEx	Brain Cerebellum	PPA2	0.22	0.01	lasso	4	0.03	3.7e-02	-10.16	-8.6	6.1e-18	0.62	0.09	0.12	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	PPA2	0.32	0.38	lasso	2	0.38	1.1e-51	7.20	-8.0	1.4e-15	0.45	1.00	0.00	FALSE
17	GTEx	Thyroid	PPA2	0.22	0.01	enet	18	0.12	2.9e-09	8.36	-7.8	6.3e-15	0.54	0.74	0.07	FALSE
10	GTEx	Heart Atrial Appendage	PPA2	0.15	0.05	lasso	7	0.06	7.4e-04	-11.71	-7.7	1.7e-14	0.71	0.24	0.38	FALSE
15	GTEx	Skin Sun Exposed Lower leg	PPA2	0.09	0.07	lasso	3	0.04	4.3e-04	7.20	-7.6	3.0e-14	0.35	0.65	0.04	FALSE
20	YFS	Blood	PPA2	0.22	0.05	lasso	19	0.12	9.7e-38	-3.71	7.3	3.2e-13	-0.51	1.00	0.00	FALSE
12	GTEx	Muscle Skeletal	PPA2	0.19	0.06	enet	28	0.11	8.7e-11	-11.28	-7.1	1.3e-12	0.60	0.89	0.11	FALSE
18	METSIM	Adipose	PPA2	0.08	0.05	lasso	2	0.04	3.7e-07	7.20	7.1	1.3e-12	-0.26	0.96	0.00	FALSE
2	GTEx	Adipose Subcutaneous	PPA2	0.15	0.02	enet	36	0.06	7.0e-06	7.30	-6.5	7.0e-11	0.34	0.26	0.11	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPA2	0.11	0.03	blup	84	0.03	4.7e-04	-10.16	-5.7	1.1e-08	0.59	0.18	0.68	FALSE
22	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPA2	0.29	0.01	blup	84	0.10	4.3e-06	-7.06	-5.2	2.5e-07	0.37	0.13	0.12	FALSE