[Hub]/) : Traits : Standing height :

chr4:105,373,669-107,092,169

Best TWAS P=6.55e-42 · Best GWAS P=1.36e-49 conditioned to 2.49e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPA2 0.08 0.03 bslmm 429 0.04 2.2e-05 -9.75 -9.9 2.7e-23 0.66 0.08 0.89 FALSE
2 GTEx Adipose Subcutaneous PPA2 0.15 0.02 enet 36 0.06 7.0e-06 7.30 -6.5 7.0e-11 0.34 0.26 0.11 FALSE
3 GTEx Artery Aorta PPA2 0.11 -0.01 enet 24 0.01 1.6e-01 -14.18 -9.1 1.0e-19 0.63 0.06 0.46 FALSE
4 GTEx Artery Tibial PPA2 0.08 0.02 enet 19 0.04 5.0e-04 -10.16 -5.2 2.0e-07 0.51 0.17 0.18 TRUE
5 GTEx Brain Cerebellum PPA2 0.22 0.01 lasso 4 0.03 3.7e-02 -10.16 -8.6 6.1e-18 0.62 0.09 0.12 FALSE
6 GTEx Brain Cortex PPA2 0.14 0.09 lasso 9 0.09 1.6e-03 -11.81 -12.0 5.4e-33 0.88 0.04 0.74 FALSE
7 GTEx Cells Transformed fibroblasts PPA2 0.11 0.03 lasso 3 0.01 6.5e-02 -8.92 -10.2 3.2e-24 0.67 0.39 0.16 FALSE
8 GTEx Esophagus Gastroesophageal Junction PPA2 0.29 0.15 lasso 5 0.14 8.8e-06 -14.18 -13.2 6.9e-40 0.88 0.02 0.96 TRUE
9 GTEx Esophagus Mucosa PPA2 0.18 0.06 enet 14 0.12 2.5e-08 13.01 -13.6 6.6e-42 0.72 0.11 0.89 TRUE
10 GTEx Heart Atrial Appendage PPA2 0.15 0.05 lasso 7 0.06 7.4e-04 -11.71 -7.7 1.7e-14 0.71 0.24 0.38 FALSE
11 GTEx Lung PPA2 0.09 0.02 enet 16 0.03 1.4e-03 0.88 -6.0 1.8e-09 0.45 0.19 0.34 TRUE
12 GTEx Muscle Skeletal PPA2 0.19 0.06 enet 28 0.11 8.7e-11 -11.28 -7.1 1.3e-12 0.60 0.89 0.11 FALSE
13 GTEx Nerve Tibial PPA2 0.13 0.07 enet 23 0.07 2.1e-05 -10.16 -9.8 7.3e-23 0.66 0.36 0.46 FALSE
14 GTEx Ovary PPA2 0.18 0.10 lasso 3 0.14 2.2e-04 -10.16 -12.0 3.2e-33 0.76 0.04 0.80 FALSE
15 GTEx Skin Sun Exposed Lower leg PPA2 0.09 0.07 lasso 3 0.04 4.3e-04 7.20 -7.6 3.0e-14 0.35 0.65 0.04 FALSE
16 GTEx Skin Sun Exposed Lower leg TET2 0.09 0.01 enet 18 0.02 3.6e-03 -14.79 -11.5 1.6e-30 0.69 0.01 0.95 FALSE
17 GTEx Thyroid PPA2 0.22 0.01 enet 18 0.12 2.9e-09 8.36 -7.8 6.3e-15 0.54 0.74 0.07 FALSE
18 METSIM Adipose PPA2 0.08 0.05 lasso 2 0.04 3.7e-07 7.20 7.1 1.3e-12 -0.26 0.96 0.00 FALSE
19 ROSMAP Brain Pre-frontal Cortex PPA2 0.32 0.38 lasso 2 0.38 1.1e-51 7.20 -8.0 1.4e-15 0.45 1.00 0.00 FALSE
20 YFS Blood PPA2 0.22 0.05 lasso 19 0.12 9.7e-38 -3.71 7.3 3.2e-13 -0.51 1.00 0.00 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPA2 0.11 0.03 blup 84 0.03 4.7e-04 -10.16 -5.7 1.1e-08 0.59 0.18 0.68 FALSE
22 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PPA2 0.29 0.01 blup 84 0.10 4.3e-06 -7.06 -5.2 2.5e-07 0.37 0.13 0.12 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma PPA2 0.04 0.02 blup 84 0.04 6.1e-05 -11.28 -10.1 6.8e-24 0.77 0.14 0.65 FALSE