Best TWAS P=2.3e-80 · Best GWAS P=1.35e-162 conditioned to 1.01e-83
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -12.5 | -11.8 | 3.1e-32 | 0.31 | 0.85 | 0.03 | TRUE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 14.3 | 14.6 | 2.1e-48 | -0.22 | 0.06 | 0.13 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -19.5 | 19.0 | 2.3e-80 | -0.39 | 0.32 | 0.12 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 14.5 | -15.0 | 9.3e-51 | 0.31 | 0.66 | 0.02 | TRUE |
| 5 | YFS | Blood | GYPE | 0.09 | 0.17 | bslmm | 255 | 0.19 | 1.5e-60 | -4.7 | -5.2 | 1.5e-07 | 0.08 | 1.00 | 0.00 | TRUE |