Best TWAS P=3.53e-10 · Best GWAS P=3.4e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | PAPD7 | 0.36 | 0.22 | lasso | 7 | 0.22 | 3.4e-10 | 6.6 | 6.3 | 3.5e-10 | 0.95 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | PAPD7 | 0.09 | 0.08 | lasso | 5 | 0.10 | 7.0e-10 | -3.2 | -5.3 | 9.0e-08 | -0.85 | 0.03 | 0.97 | FALSE |