[Hub]/) : Traits : Standing height :

chr5:12,225-1,169,112

Best TWAS P=2.94e-14 · Best GWAS P=4.3e-12 conditioned to 0.0156

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AHRR 0.25 0.18 lasso 12 0.21 1.2e-25 6.0 6.3 2.2e-10 0.49 0.26 0.74 FALSE
2 CommonMind Brain Pre-frontal Cortex SDHA 0.12 0.06 bslmm 290 0.11 8.6e-14 5.9 -5.3 9.9e-08 -0.58 0.53 0.47 FALSE
3 GTEx Adipose Subcutaneous SDHA 0.10 0.09 lasso 5 0.07 1.9e-06 6.0 6.3 2.5e-10 0.53 0.25 0.75 FALSE
4 GTEx Adipose Visceral Omentum SDHA 0.10 0.05 lasso 3 0.07 1.5e-04 6.1 5.9 3.0e-09 0.48 0.20 0.42 FALSE
5 GTEx Adipose Visceral Omentum CCDC127 0.13 0.03 lasso 4 0.05 9.0e-04 6.3 6.7 1.7e-11 0.74 0.03 0.95 FALSE
6 GTEx Artery Aorta PDCD6 0.26 0.17 lasso 4 0.14 2.8e-08 6.0 -5.5 4.2e-08 -0.52 0.30 0.70 FALSE
7 GTEx Brain Cerebellum CTD-2083E4.5 0.14 0.01 lasso 10 0.03 5.9e-02 4.6 -5.8 5.9e-09 -0.30 0.09 0.14 FALSE
8 GTEx Brain Frontal Cortex BA9 AHRR 0.32 0.21 lasso 4 0.18 1.6e-05 6.0 5.8 6.5e-09 0.51 0.10 0.23 FALSE
9 GTEx Cells Transformed fibroblasts SDHA 0.23 0.18 lasso 2 0.17 1.6e-12 6.0 6.1 1.4e-09 0.53 0.28 0.72 FALSE
10 GTEx Cells Transformed fibroblasts CCDC127 0.25 0.13 lasso 5 0.14 9.0e-11 4.5 5.5 3.7e-08 0.49 0.57 0.43 FALSE
11 GTEx Cells Transformed fibroblasts CTD-2083E4.5 0.09 0.07 lasso 3 0.05 1.2e-04 6.1 -5.7 1.1e-08 -0.52 0.20 0.56 FALSE
12 GTEx Heart Atrial Appendage SDHA 0.15 0.04 lasso 3 0.02 4.3e-02 6.3 -6.2 5.5e-10 -0.82 0.02 0.94 FALSE
13 GTEx Nerve Tibial CCDC127 0.05 0.01 lasso 4 0.02 2.2e-02 6.3 6.7 2.9e-11 0.80 0.04 0.81 FALSE
14 GTEx Testis SDHA 0.33 0.24 lasso 7 0.20 2.9e-09 4.4 6.3 4.0e-10 0.33 0.95 0.05 FALSE
15 GTEx Thyroid EXOC3 0.16 0.04 lasso 5 0.06 3.6e-05 5.4 5.8 6.9e-09 0.28 0.48 0.41 FALSE
16 GTEx Thyroid CTD-2083E4.5 0.07 0.06 lasso 2 0.04 3.6e-04 6.1 -6.5 7.7e-11 -0.53 0.16 0.56 FALSE
17 GTEx Whole Blood SDHA 0.05 0.01 lasso 5 0.01 3.4e-02 5.1 -5.2 1.8e-07 -0.62 0.19 0.41 FALSE
18 METSIM Adipose SDHA 0.09 0.04 lasso 12 0.03 8.5e-06 5.9 5.6 2.4e-08 0.55 0.44 0.56 FALSE
19 NTR Blood CCDC127 0.02 0.01 blup 284 0.02 1.5e-06 5.2 -6.2 6.6e-10 -0.45 0.76 0.19 FALSE
20 ROSMAP Brain Pre-frontal Cortex SDHA 0.07 0.04 lasso 4 0.04 2.3e-06 5.2 -5.6 2.2e-08 -0.25 0.92 0.04 FALSE
21 YFS Blood PDCD6 0.03 0.03 bslmm 276 0.03 1.6e-09 6.1 6.9 6.0e-12 0.60 0.39 0.61 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma AHRR 0.04 0.03 lasso 3 0.03 1.1e-06 5.9 7.6 2.9e-14 0.68 0.02 0.98 TRUE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDCD6 0.03 0.02 blup 49 0.02 2.9e-03 5.9 6.1 1.4e-09 0.66 0.24 0.38 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SDHA 0.04 0.03 blup 62 0.05 3.3e-06 6.1 6.6 5.2e-11 0.49 0.03 0.97 FALSE
25 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRRC14B 0.08 0.04 lasso 5 0.03 6.7e-03 5.9 5.9 4.3e-09 0.58 0.01 0.95 FALSE
26 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SDHA 0.05 0.02 lasso 4 0.01 1.3e-01 4.5 5.7 1.4e-08 0.47 0.02 0.77 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma AHRR 0.30 0.17 lasso 3 0.25 7.9e-28 5.9 7.5 8.2e-14 0.65 0.42 0.58 FALSE
28 The Cancer Genome Atlas Liver Hepatocellular Carcinoma AHRR 0.11 0.05 lasso 3 0.07 2.5e-04 6.0 6.4 1.2e-10 0.42 0.11 0.21 FALSE
29 The Cancer Genome Atlas Lung Adenocarcinoma AHRR 0.05 0.01 blup 99 0.01 1.4e-02 3.6 6.1 8.7e-10 0.35 0.10 0.32 FALSE
30 The Cancer Genome Atlas Stomach Adenocarcinoma AHRR 0.04 0.03 blup 100 0.04 9.1e-04 3.2 6.1 8.6e-10 0.37 0.05 0.38 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma AHRR 0.13 0.04 blup 100 0.08 1.3e-08 5.9 5.6 2.1e-08 0.33 0.67 0.28 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma PDCD6 0.07 0.06 enet 5 0.07 2.0e-07 6.1 -5.2 1.8e-07 -0.53 0.34 0.65 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma SDHA 0.06 0.09 lasso 13 0.08 1.8e-08 6.1 6.0 2.0e-09 0.54 0.02 0.98 FALSE