Best TWAS P=6.27e-20 · Best GWAS P=4e-19 conditioned to 0.0562
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | CDO1 | 0.12 | 0.04 | lasso | 6 | 0.05 | 7.0e-05 | 8.8 | -8.5 | 1.9e-17 | -0.81 | 0.01 | 0.99 | FALSE |
2 | GTEx | Artery Aorta | CDO1 | 0.27 | 0.15 | enet | 16 | 0.15 | 1.7e-08 | 8.8 | -8.3 | 7.8e-17 | -0.85 | 0.01 | 0.99 | FALSE |
3 | GTEx | Artery Tibial | CDO1 | 0.24 | 0.15 | lasso | 6 | 0.12 | 5.3e-10 | 8.8 | -9.1 | 6.3e-20 | -0.88 | 0.00 | 1.00 | TRUE |
4 | METSIM | Adipose | CDO1 | 0.07 | 0.01 | bslmm | 537 | 0.02 | 7.9e-04 | 8.8 | -8.1 | 4.7e-16 | -0.63 | 0.00 | 0.98 | FALSE |