Best TWAS P=1.39e-07 · Best GWAS P=2.29e-09 conditioned to 0.000875
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CTC-487M23.5 | 0.07 | 0.03 | lasso | 3 | 0.03 | 0.0029 | -4.7 | -5.3 | 1.4e-07 | 0.66 | 0.05 | 0.83 | TRUE |
| 2 | YFS | Blood | SRP19 | 0.02 | 0.01 | bslmm | 456 | 0.00 | 0.0287 | 4.6 | 5.2 | 2.4e-07 | -0.67 | 0.03 | 0.82 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | APC | 0.02 | 0.02 | enet | 5 | 0.02 | 0.0042 | -5.0 | 5.2 | 1.7e-07 | -0.74 | 0.02 | 0.88 | FALSE |