Best TWAS P=1.17e-12 · Best GWAS P=2.95e-11 conditioned to 3.83e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | SCMH1 | 0.09 | 0.01 | lasso | 3 | 0.00 | 1.4e-01 | 2.5 | 5.4 | 6.5e-08 | -0.56 | 0.13 | 0.66 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | FOXO6 | 0.27 | 0.16 | lasso | 6 | 0.32 | 1.0e-24 | -5.6 | -7.1 | 1.2e-12 | 0.41 | 0.84 | 0.16 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | FOXO6 | 0.07 | 0.03 | enet | 14 | 0.05 | 1.5e-06 | -4.6 | -6.8 | 1.1e-11 | 0.35 | 0.69 | 0.26 | FALSE |