TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Qualifications: College or University degree
:
←
→
chr1:71,163,715-73,435,171
Best TWAS P=1.7e-23 · Best GWAS P=2.05e-16 conditioned to 0.321
71.5M
72M
72.5M
73M
73.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
NEGR1
0.24
0.15
lasso
8
0.22
1.3e-27
7.8
10
1.7e-23
-0.76
0.05
0.95
TRUE