Best TWAS P=1.47e-10 · Best GWAS P=1.93e-10 conditioned to 0.0472
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CALN1 | 0.05 | 0.02 | lasso | 4 | 0.01 | 1.0e-02 | -6.2 | 6.4 | 1.5e-10 | -0.93 | 0.02 | 0.98 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CALN1 | 0.11 | 0.08 | bslmm | 475 | 0.07 | 9.5e-10 | -4.9 | 5.2 | 1.7e-07 | -0.71 | 0.52 | 0.48 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | WBSCR17 | 0.08 | 0.01 | blup | 313 | 0.04 | 1.7e-05 | 2.1 | -5.7 | 1.0e-08 | -0.06 | 0.02 | 0.02 | TRUE |