TWAS hub - CPNE3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1660	0.0360	1.6e-11	0.070	0.097	0.084	0.094	0.077	7.2e-09	7.9e-12	2.0e-10	1.5e-11	1.1e-09
2	GTEx	Adipose Subcutaneous	0.1200	0.0380	2.2e-05	0.012	NA	0.052	NA	0.041	3.3e-02	NA	4.6e-05	NA	2.7e-04
3	GTEx	Artery Aorta	0.1750	0.0630	5.9e-04	0.010	NA	0.049	NA	0.029	9.2e-02	NA	1.0e-03	NA	9.8e-03
4	GTEx	Artery Tibial	0.0986	0.0408	4.7e-04	0.040	NA	0.047	NA	0.038	4.1e-04	NA	1.4e-04	NA	5.7e-04
5	GTEx	Brain Putamen basal ganglia	0.2480	0.1040	4.7e-03	0.001	NA	0.015	NA	0.013	2.9e-01	NA	1.4e-01	NA	1.5e-01
6	GTEx	Cells Transformed fibroblasts	0.1970	0.0480	9.8e-10	0.119	NA	0.132	NA	0.125	3.1e-09	NA	4.3e-10	NA	1.3e-09
7	GTEx	Colon Sigmoid	0.1460	0.0640	4.2e-03	-0.001	NA	0.007	NA	-0.004	3.6e-01	NA	1.8e-01	NA	4.8e-01
8	GTEx	Colon Transverse	0.4190	0.0840	1.4e-08	0.058	NA	0.258	NA	0.199	9.6e-04	NA	1.2e-12	NA	7.8e-10
9	GTEx	Esophagus Gastroesophageal Junction	0.2250	0.0770	2.4e-04	0.167	NA	0.153	NA	0.138	1.2e-06	NA	3.5e-06	NA	1.1e-05
10	GTEx	Esophagus Mucosa	0.3870	0.1080	1.2e-03	0.009	NA	0.019	NA	0.010	7.8e-02	NA	1.8e-02	NA	7.1e-02
11	GTEx	Esophagus Muscularis	0.0860	0.0400	5.3e-03	0.023	NA	0.018	NA	0.020	1.4e-02	NA	2.8e-02	NA	2.0e-02
12	GTEx	Lung	0.1139	0.0448	1.6e-03	0.011	NA	0.009	NA	0.022	4.4e-02	NA	6.0e-02	NA	7.3e-03
13	GTEx	Muscle Skeletal	0.0999	0.0434	3.0e-03	0.075	NA	0.071	NA	0.072	7.9e-08	NA	1.7e-07	NA	1.3e-07
14	GTEx	Nerve Tibial	0.1496	0.0463	1.1e-04	0.023	NA	0.091	NA	0.067	9.0e-03	NA	5.3e-07	NA	1.7e-05
15	GTEx	Pancreas	0.1110	0.0430	1.4e-03	0.013	NA	-0.005	NA	-0.005	9.2e-02	NA	5.7e-01	NA	6.2e-01
16	GTEx	Testis	0.1260	0.0560	5.0e-03	0.000	NA	-0.004	NA	-0.005	3.3e-01	NA	5.2e-01	NA	6.5e-01
17	NTR	Blood	0.0175	0.0080	3.6e-03	0.006	0.007	0.004	0.006	0.005	2.9e-03	2.1e-03	1.5e-02	2.7e-03	9.1e-03
18	ROSMAP	Brain Pre-frontal Cortex	0.0926	0.0328	1.9e-04	0.027	0.040	0.046	0.044	0.042	1.8e-04	5.7e-06	1.2e-06	2.2e-06	3.5e-06
19	YFS	Blood	0.0917	0.0210	1.1e-16	0.051	0.066	0.063	0.065	0.067	2.0e-16	1.4e-20	7.1e-20	1.9e-20	6.5e-21
20	TCGA	Kidney Renal Clear Cell Carcinoma	0.0687	0.0302	3.0e-05	0.029	0.044	0.033	NA	0.050	2.9e-04	1.0e-05	1.1e-04	NA	2.3e-06
21	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1780	0.0730	1.1e-06	0.044	0.099	0.056	NA	0.078	1.5e-03	2.7e-06	4.0e-04	NA	3.0e-05
22	TCGA	Lung Adenocarcinoma	0.0446	0.0310	4.0e-03	0.000	0.021	0.005	NA	0.003	3.1e-01	1.5e-03	6.9e-02	NA	1.1e-01
23	TCGA	Prostate Adenocarcinoma	0.1043	0.0408	3.7e-09	0.074	0.095	0.086	NA	0.096	3.6e-08	3.6e-10	2.9e-09	NA	3.3e-10
24	TCGA	Thyroid Carcinoma	0.1000	0.0390	8.9e-08	0.029	0.064	0.039	NA	0.022	7.9e-04	7.1e-07	1.1e-04	NA	2.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Heart attack/myocardial infarction (self-reported)	4.8	6.2	13.6	2.0	3.2	2.2	3.7	2.7	-0.9	2.4	2.8	-0.2	2.2	3.3	2.3	2.0	3.3	2.2	3.0	1.6	2.9	3.0	2.9	3.3	1.3	1.9
Heart attack	4.2	5.4	12.5	1.8	3.1	2.2	3.5	2.3	-0.8	2.3	2.6	-0.2	2.2	3.1	2.2	2.1	2.9	2.0	2.9	1.5	2.7	2.6	2.6	3.0	1.5	1.5
Age at first live birth	3.5	6.3	27.2	1.3	2.8	0.3	1.6	3.0	2.3	2.6	2.0	2.3	0.3	1.5	2.0	-0.0	4.3	-1.3	5.2	2.9	2.3	3.8	3.3	2.4	-1.4	3.0
Age when periods started (menarche)	3.4	8.1	21.3	0.9	3.3	4.0	3.8	4.6	-1.5	3.0	2.3	0.3	3.6	3.9	1.1	1.8	3.9	2.0	3.7	0.2	1.9	3.2	3.7	3.5	1.4	2.1
Qualifications: College or University degree	3.4	10.7	41.8	2.6	4.7	0.3	2.3	4.9	2.3	2.3	3.8	1.9	1.6	2.1	1.3	-0.4	6.0	-0.3	6.5	3.1	2.0	4.0	4.3	3.5	-1.7	4.4
Medication: Ramipril	3.2	4.1	10.2	1.1	2.6	2.5	3.1	1.0	0.0	3.2	2.4	0.6	1.1	2.5	3.2	2.3	1.2	0.3	2.0	2.3	3.0	2.3	2.1	1.6	1.2	1.3
Average weekly fortified wine intake	3.1	3.7	18.8	1.2	2.8	1.0	2.5	2.2	1.3	1.4	2.1	0.9	0.9	2.4	-0.1	0.0	4.3	1.6	2.5	1.0	1.3	2.3	1.7	2.5	-1.0	2.2
Angina (self-reported)	3.1	4.1	11.4	0.3	2.7	2.1	3.0	1.2	-0.3	2.6	2.5	1.0	1.9	3.4	2.1	3.0	0.7	2.4	1.2	1.0	2.9	1.4	1.4	2.5	2.4	0.5
Heart disease (mother)	3.1	3.8	12.5	-2.5	-1.7	-1.3	-2.4	-3.5	-0.3	-1.5	-2.8	0.3	-1.1	-2.5	-0.1	-0.1	-2.2	-1.6	-1.2	-0.9	-1.3	-2.4	-2.0	-3.5	1.2	-3.1
Reason for reducing amount of alcohol drunk: Health precaution	3.0	3.5	10.0	-1.7	-1.5	-2.4	-2.5	-3.2	1.3	-1.1	-2.7	2.0	-1.1	-2.9	0.2	-1.1	-1.9	-1.6	-1.2	-0.5	-0.9	-1.9	-1.8	-3.1	1.0	-2.5
Leg fat percentage (left)	3.0	10.7	32.0	-5.6	-3.1	0.6	-1.1	-5.1	-2.7	-2.3	-2.2	-0.1	-0.2	-2.8	-0.9	1.1	-4.2	-0.4	-5.1	-2.7	-2.3	-5.7	-3.8	-4.7	3.5	-5.0
Alcohol drinker status: Previous	2.7	3.1	11.2	-2.2	-2.2	-1.0	-0.6	-2.2	-3.4	-2.1	-1.7	0.1	0.4	-1.5	-0.5	-1.0	-1.4	0.9	-2.4	-2.0	-1.6	-3.0	-0.9	-2.6	0.9	-1.8
Angina	2.6	3.4	9.8	0.3	2.5	1.8	2.7	1.0	-0.6	2.3	2.1	0.8	1.7	3.1	2.1	2.8	0.4	2.1	1.1	0.9	2.7	1.3	1.4	2.2	2.3	0.5
Alcohol usually taken with meals	2.6	4.2	10.6	2.2	2.6	0.5	1.4	3.3	2.8	1.9	2.0	1.1	0.2	2.1	1.2	0.9	2.7	0.7	2.9	2.1	2.1	2.8	2.0	2.7	-1.2	2.6
Qualifications: nursing, teaching	2.6	4.0	15.6	4.0	1.9	-0.3	1.3	2.9	0.4	0.3	1.6	0.8	-0.9	0.9	-0.2	-1.3	3.2	-1.6	3.6	1.9	0.9	2.9	1.0	2.4	-2.8	2.6
Irritability	2.6	4.5	10.6	-0.6	-3.3	-2.1	-1.8	-2.6	-1.6	-2.2	-1.5	-1.1	-2.1	-3.1	-1.7	-2.6	-2.6	-1.2	-3.1	-1.2	-2.5	-2.4	-2.2	-2.6	-1.8	-1.0
Time employed in main current job	2.5	2.9	9.3	-1.9	-1.6	-1.4	-2.2	-2.5	0.7	-1.3	-2.2	0.6	-0.3	-1.8	-1.4	-0.8	-0.8	0.3	-0.9	-1.7	-1.9	-3.1	-2.5	-2.4	1.0	-2.6
Comparative body size at age 10	2.5	6.8	22.3	-2.1	-1.9	-0.6	-2.3	-3.9	1.8	-2.8	-1.5	-0.5	-1.7	-2.4	-2.4	-1.1	-2.6	0.3	-3.7	-2.4	-2.7	-4.7	-4.7	-3.3	0.8	-4.0
Hayfever/allergic rhinitis (self-reported)	2.4	3.1	8.6	2.9	0.7	0.9	1.9	2.6	-0.8	1.0	2.5	-0.7	-0.9	1.7	1.2	1.1	1.1	0.2	1.3	2.5	2.1	2.8	1.3	2.5	-1.9	2.8
Qualifications: A levels/AS levels or equivalent	2.4	5.3	22.2	3.0	1.9	-2.0	0.1	2.0	1.2	0.4	0.5	2.2	-0.9	-0.2	0.1	-2.6	4.7	-2.7	4.6	1.7	0.6	3.1	2.2	1.7	-2.9	3.4
Leg fat percentage (right)	2.4	8.7	27.7	-5.1	-2.6	1.2	-0.4	-4.6	-2.6	-1.9	-1.4	-0.2	-0.2	-2.2	-0.4	1.5	-4.0	-0.2	-4.9	-2.1	-1.7	-5.3	-3.6	-4.1	3.5	-4.4
Sensitivity / hurt feelings	2.2	3.8	12.5	-1.9	-3.0	-0.8	-1.8	-3.5	0.0	-0.8	-2.5	-1.8	-1.1	-2.5	-1.1	-0.5	-2.2	-0.8	-2.0	-1.7	-1.9	-2.4	-2.2	-2.9	0.5	-2.8
Length of working week for main job	2.2	2.5	7.2	2.1	0.7	0.6	2.1	2.1	1.1	0.9	2.2	0.6	0.0	0.9	1.1	1.0	2.7	0.2	2.4	2.0	1.7	2.2	1.7	1.8	-0.8	1.7
Ever highly irritable/argumentative for 2 days	2.2	2.6	9.6	-2.5	-1.8	1.0	0.0	-1.1	-0.5	-1.3	-0.3	-1.5	1.2	-1.7	-2.5	-1.4	-0.4	1.0	-3.1	-2.3	-2.9	-2.4	-0.4	-1.6	0.4	-1.1
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	7.7	-2.6	-1.5	-1.8	-2.0	-2.8	-0.8	-1.3	-2.8	0.3	-0.2	-1.7	-0.3	-0.5	-2.6	-1.0	-1.5	-1.3	-1.1	-1.8	-1.0	-2.0	1.3	-2.2
Illnesses of mother	2.1	2.6	8.3	2.1	1.1	1.9	1.9	1.4	0.0	2.3	2.9	-0.6	0.7	1.4	2.0	1.2	0.7	0.7	1.8	2.1	2.0	1.5	1.5	2.2	-0.0	2.0
Verbal and Numeric Reasoning (VNR)	2.0	4.9	18.8	3.3	2.1	-0.6	0.8	3.4	0.4	1.2	0.9	0.3	0.7	0.5	0.1	-1.2	4.0	-0.8	3.3	1.6	0.5	4.3	3.5	2.4	-2.5	3.4
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	9.1	-1.0	-3.0	-1.0	-2.4	-2.9	-0.5	-0.3	-2.6	-1.4	-1.0	-1.9	-0.3	-0.7	-1.9	-1.0	-2.1	-0.9	-0.7	-1.2	-1.1	-1.0	0.4	-0.9
Qualifications: None of the above	2.0	4.3	15.7	-4.0	-2.2	1.0	-0.5	-2.8	-1.9	0.2	-2.0	-0.4	1.0	-0.5	0.3	1.7	-2.7	2.0	-3.8	-2.1	-0.7	-2.7	-0.7	-2.4	3.2	-2.8
Mouth/teeth dental problems: Dentures	2.0	3.4	11.0	-2.2	-2.0	-0.7	-1.6	-1.9	-1.8	-1.8	-3.0	-0.6	0.1	-1.8	-1.4	-0.5	-2.4	0.0	-3.3	-2.6	-2.1	-2.1	-0.7	-2.8	1.1	-2.1
Alcohol intake frequency.	2.0	4.8	15.7	-3.3	-3.3	-1.3	-1.5	-3.0	-2.7	-2.3	-1.8	-0.7	-0.7	-2.1	-0.8	-0.1	-4.0	-0.2	-3.9	-1.5	-1.6	-3.1	-1.8	-2.3	0.7	-1.7
Commuting to job workplace: Car/motor vehicle	2.0	2.3	7.9	-2.8	-0.4	1.0	0.7	-0.4	0.2	0.5	-1.3	-0.9	2.7	0.3	-1.5	0.3	0.3	2.4	-1.6	-2.8	-1.7	-1.4	0.0	-1.1	2.5	-2.2
Medication: Omeprazole (e.g. Zanprol)	2.0	2.4	7.4	-0.5	2.7	2.4	1.3	0.4	0.1	2.1	1.4	-1.4	1.2	1.9	2.6	2.5	-0.5	1.8	0.2	0.5	2.0	-0.3	1.2	0.0	2.6	0.2
Health satisfaction	1.9	2.5	9.2	-3.0	-2.0	-0.6	-0.6	-2.5	-1.4	-0.6	-0.9	1.2	-0.5	-2.5	-0.2	-0.6	-1.3	0.5	-2.6	-0.8	-1.3	-2.3	-1.0	-2.8	0.6	-1.5
Age at last live birth	1.9	2.7	15.4	0.9	1.8	0.6	1.2	2.2	2.1	1.6	1.2	0.4	0.9	0.9	0.0	-0.6	3.9	-0.2	3.1	1.0	0.5	2.8	2.3	1.3	-1.2	1.1
Intelligence (Savage-Jansen 2018)	1.8	5.5	22.6	3.2	3.4	0.8	1.3	3.5	1.6	1.6	1.2	0.6	1.2	1.5	0.2	-0.3	4.8	-0.0	3.4	1.4	0.9	4.3	3.1	2.9	-1.5	3.1
Multivitamins +/- minerals	1.8	2.3	9.9	2.0	1.9	1.2	1.3	3.1	1.0	0.6	2.0	0.3	-0.2	1.4	0.2	0.2	1.3	-0.4	1.2	1.5	1.0	2.2	1.0	2.2	-1.9	2.5
Number of live births	1.8	2.5	7.6	-0.3	-1.5	-0.1	-1.1	-1.8	-2.6	-1.5	-1.4	-2.8	-0.1	-1.6	-1.5	-1.1	-2.3	-1.0	-2.3	-1.6	-2.0	-1.8	-1.2	-1.9	-0.2	-1.6
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	10.4	3.2	1.3	-1.6	1.1	2.0	0.5	-0.6	0.9	0.9	-0.9	0.1	-0.1	-2.0	2.6	-1.9	2.6	1.6	0.4	2.3	0.9	1.5	-2.9	2.5
Body fat percentage	1.8	7.0	22.6	-4.8	-2.0	1.7	-0.1	-3.8	-3.0	-1.4	-1.2	-0.1	0.8	-1.4	-0.2	2.0	-3.4	0.2	-4.1	-2.3	-1.3	-4.5	-2.6	-3.3	4.0	-4.0
Pack years adult smoking proportion	1.7	2.5	11.7	-1.6	1.3	2.6	0.8	1.0	-1.0	0.9	-0.4	-0.9	3.2	2.3	-0.2	1.5	0.2	2.1	-0.4	-2.7	-0.1	-0.0	1.1	0.9	3.4	-1.2
Medication: Omeprazole	1.7	2.0	7.8	-1.1	2.2	2.1	1.4	-0.2	-0.2	1.7	1.6	-1.3	1.0	1.6	2.0	2.2	-0.4	2.1	-0.3	0.2	1.5	-1.2	0.1	-0.4	2.8	-0.7
Schizophrenia vs Biploar Disorder	1.6	2.1	7.1	0.9	2.5	0.9	1.3	1.5	-0.4	1.8	0.7	-0.4	1.1	1.5	1.5	0.7	2.2	-0.6	2.7	0.6	1.4	2.4	2.2	1.6	0.3	1.3
Alzheimer’s Disease (in mother)	1.6	1.9	5.2	1.9	1.8	1.4	1.6	2.2	0.9	0.7	1.8	0.6	1.0	1.9	0.3	0.7	1.8	0.7	1.2	0.4	1.1	1.4	1.1	2.3	-0.1	1.7
Reaction Time	1.6	3.0	12.4	-0.6	-1.5	-1.1	-0.6	-3.1	-3.5	-1.3	-1.7	0.8	-1.1	-1.2	0.1	-0.3	-3.5	-2.1	-0.4	-1.3	-0.5	-2.4	-2.5	-1.7	1.1	-1.9
Height	1.6	30.6	88.4	2.6	6.7	6.1	7.8	7.3	0.5	6.6	6.9	0.2	4.8	8.3	3.3	5.0	4.9	3.1	5.2	3.2	5.7	6.5	5.8	9.4	1.3	6.3
Ever had hysterectomy (womb removed)	1.6	1.8	6.0	-0.2	-1.8	-0.7	-2.5	-2.1	0.2	-1.1	-1.9	-0.7	-1.8	-2.3	0.1	-0.6	-1.9	-1.6	-1.2	0.2	-0.5	-1.3	-1.4	-1.4	-0.1	-0.6
Loud music exposure frequency	1.6	1.8	9.1	-1.1	-2.1	-1.0	-0.6	-0.8	0.3	-1.3	-1.0	1.3	-0.1	-1.6	-1.1	-0.5	-0.7	1.8	-3.0	-1.4	-1.5	-1.8	-1.1	-1.6	0.4	-1.4
Medication: Ibuprofen	1.6	1.9	5.6	0.3	1.3	1.3	2.3	1.2	0.6	2.4	1.7	1.3	1.4	1.4	1.9	1.1	1.2	2.1	0.9	1.0	1.5	0.5	1.7	0.8	1.4	0.8
Family relationship satisfaction	1.6	2.0	4.6	1.5	1.4	0.6	0.8	1.9	1.8	1.5	1.8	0.6	0.2	1.2	1.6	0.2	1.0	0.3	2.0	1.9	1.7	1.7	2.0	1.3	-0.7	2.1
Pack years of smoking	1.6	2.3	12.8	-1.7	1.3	2.3	0.4	0.8	-0.9	0.7	-0.6	-0.6	3.0	2.1	0.3	1.8	-0.2	1.9	-0.4	-2.3	0.3	0.2	1.3	0.9	3.6	-1.1
Leg fat mass (left)	1.6	6.4	23.7	-4.9	-1.4	2.5	1.0	-3.4	-2.4	-0.9	0.1	0.1	0.8	-0.7	0.1	2.5	-3.2	0.9	-4.4	-1.7	-0.7	-4.5	-2.8	-2.4	4.0	-3.5
Coronary Artery Disease (CAD)	1.5	1.8	9.7	0.4	2.4	0.5	0.3	0.8	0.7	1.9	-0.9	-0.5	1.7	1.0	0.7	0.6	2.3	0.1	3.1	-0.1	0.4	1.7	2.3	1.0	1.2	0.6
Primary Biliary Cirrhosis	1.5	2.2	6.2	-0.5	-1.5	-2.2	-1.7	-2.3	-0.9	-1.0	-1.7	0.2	-1.5	-2.2	-0.7	-1.1	-1.4	-1.9	-1.1	-0.3	-1.3	-1.4	-1.8	-2.5	-0.7	-1.9
Diabetes (father)	1.5	1.8	8.5	0.7	0.9	1.1	0.7	2.6	0.2	1.3	0.6	0.8	1.2	0.9	1.6	0.7	1.0	0.7	2.4	0.5	1.2	2.3	2.9	1.1	0.4	1.4
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	6.8	2.0	0.3	-0.6	-0.1	1.0	1.3	0.4	0.7	-0.6	-0.9	0.1	1.1	-0.3	1.4	-1.2	1.5	1.8	1.2	2.6	1.9	1.3	-1.7	2.5
Diabetes (self-reported)	1.5	2.3	5.2	-0.8	1.9	2.0	1.8	1.4	0.3	2.3	1.8	-0.7	1.0	1.9	1.7	1.9	1.2	-0.7	2.2	1.1	1.8	1.3	1.9	1.6	1.1	1.6
Leg fat mass (right)	1.5	5.8	21.0	-4.6	-1.1	2.7	1.2	-3.1	-2.2	-0.7	0.4	0.1	0.7	-0.4	0.3	2.7	-3.2	0.8	-4.2	-1.4	-0.4	-4.2	-2.7	-2.1	3.8	-3.1
Myopia	1.5	2.1	5.3	1.3	1.6	0.6	0.7	1.4	1.8	2.0	1.8	-0.4	-0.4	1.7	1.7	1.2	0.6	0.4	1.2	1.9	2.3	2.3	1.3	2.1	-0.6	2.0
BMI	1.4	8.0	29.7	-5.4	-1.8	2.0	-0.3	-4.0	-1.4	-1.5	-0.7	0.3	0.6	-1.5	-0.3	1.8	-3.7	0.6	-4.3	-2.5	-1.3	-5.4	-3.3	-3.3	4.4	-4.2
Trunk fat percentage	1.4	5.7	18.4	-4.3	-1.7	1.6	-0.0	-3.3	-3.0	-1.3	-1.2	0.2	0.9	-1.2	-0.1	2.0	-3.1	0.1	-3.6	-2.1	-1.1	-3.9	-2.1	-2.9	3.8	-3.5
Taking other prescription medications	1.4	2.2	13.8	-3.7	0.8	0.8	0.7	-1.6	0.6	2.0	-0.5	1.7	1.8	0.2	1.2	1.2	1.2	1.9	0.1	-0.6	0.4	-1.3	1.1	-1.4	3.1	-1.2
Body mass index (BMI)	1.4	5.9	20.2	-4.5	-1.2	2.5	0.5	-3.2	-1.3	-1.0	0.2	-0.4	0.6	-0.6	0.0	2.6	-3.3	1.1	-4.4	-1.7	-0.6	-4.4	-2.9	-2.2	3.8	-3.4
Fluid intelligence score	1.4	2.9	12.2	2.4	1.4	-0.1	-0.4	3.0	1.8	1.2	0.5	0.3	0.3	0.3	-0.7	-1.6	3.5	-1.1	2.7	0.8	-0.2	2.8	2.1	1.6	-2.1	2.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.7	5.2	1.1	1.0	1.0	2.2	1.3	0.3	2.3	1.8	1.2	0.7	1.2	1.6	0.9	0.8	1.7	0.7	1.4	1.5	1.2	1.8	1.3	0.3	1.6
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	4.8	2.1	1.1	1.4	1.5	1.1	-0.7	1.2	1.6	-1.0	0.4	0.8	1.3	0.5	0.2	-1.2	1.7	1.5	1.3	2.1	2.2	1.5	-0.7	1.8
Illnesses of siblings: Diabetes	1.4	1.8	6.2	-1.9	2.5	2.3	1.5	1.2	-0.1	0.5	0.4	0.8	2.3	1.7	-0.2	1.5	1.5	0.8	0.3	-1.3	0.0	-0.2	1.5	1.1	1.9	0.3
Arm fat percentage (left)	1.4	5.7	20.0	-4.5	-1.8	1.9	0.2	-3.4	-1.9	-0.9	-0.4	0.0	0.7	-1.1	0.2	2.2	-3.1	0.6	-3.9	-1.7	-0.8	-4.1	-2.4	-2.9	3.7	-3.6
Commuting to job workplace: Walk	1.4	1.6	6.3	1.5	-0.7	-2.0	-1.0	-0.2	1.0	-1.0	0.0	1.6	-2.5	-1.5	0.8	-0.9	-0.0	-2.0	0.5	1.9	0.5	0.8	-0.5	-0.3	-2.1	1.3
Commuting to job workplace: Public transport	1.4	1.7	10.0	0.7	2.1	0.8	0.3	0.5	-1.4	0.6	0.6	0.9	-0.2	1.2	2.1	1.1	-0.1	-1.2	3.2	1.2	2.1	1.3	1.0	1.3	0.4	1.4
Triglycerides	1.3	2.2	5.6	-1.6	-1.3	-0.7	-1.7	-2.0	-1.0	-2.2	-2.4	-0.7	0.1	-1.7	-1.4	-1.3	-1.0	-1.0	-0.9	-1.9	-2.1	-1.8	-1.1	-2.0	0.3	-1.8
Average weekly spirits intake	1.3	1.6	7.4	-2.3	-1.6	1.3	-0.1	-1.9	-1.3	0.1	-1.3	0.1	1.6	-0.6	0.4	0.4	-0.7	1.0	-0.4	-1.4	-0.6	-1.3	0.1	-1.5	2.7	-2.0
Maternal smoking around birth	1.3	1.9	4.9	0.0	-1.4	-0.9	-1.2	-2.2	-1.0	-1.3	-1.6	-0.3	-0.9	-1.1	-1.8	-1.7	-0.6	-0.7	-1.9	-1.8	-2.0	-1.7	-1.8	-1.6	-0.5	-1.6
Had other major operations	1.3	1.6	4.1	0.1	2.0	1.8	1.5	1.2	-1.4	1.5	0.9	0.1	0.9	1.8	1.9	1.8	0.2	0.2	0.8	0.8	1.8	0.9	1.2	1.3	1.2	1.1
Arm fat percentage (right)	1.3	5.3	17.5	-4.2	-1.6	1.8	0.2	-3.3	-1.9	-1.0	-0.3	-0.1	0.6	-0.9	0.2	2.1	-3.0	0.6	-3.8	-1.7	-0.7	-4.0	-2.5	-2.7	3.6	-3.5
Medication: Lansoprazole	1.3	1.5	6.5	-2.4	0.4	0.6	-0.0	-0.9	-1.2	1.2	-0.8	0.9	2.1	0.6	0.9	1.2	-0.5	1.9	-0.6	-1.4	0.2	-0.8	1.1	-1.3	2.6	-1.5
Lung cancer (father)	1.3	1.5	5.4	-1.2	-1.4	-0.6	-0.9	-1.3	-0.7	-1.1	-0.6	0.6	-0.8	-0.8	-1.4	-0.2	0.1	1.3	-2.2	-1.3	-1.3	-2.3	-2.0	-1.5	0.5	-1.4
Glaucoma (self-reported)	1.3	1.6	5.9	2.4	1.4	0.3	0.2	1.3	-0.4	-0.4	2.0	-0.5	-1.3	0.4	1.2	0.2	1.0	-0.9	1.7	2.4	1.5	1.5	0.2	1.3	-1.3	1.4
Eye problems/disorders: Cataract	1.3	1.5	5.8	1.0	1.3	-0.0	1.0	1.0	0.6	1.8	1.1	0.5	-0.0	0.6	2.1	0.0	0.2	0.1	1.1	2.4	1.6	1.5	2.0	0.9	-0.8	1.8
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	11.7	1.9	-0.9	-0.9	-0.8	-1.2	0.8	0.3	0.0	-0.5	-3.4	-1.4	0.8	-0.6	-1.9	-3.2	0.4	1.9	0.5	0.2	-1.8	-0.8	-2.2	0.3
Breast cancer (self-reported)	1.3	1.6	4.8	0.1	1.1	2.1	2.2	0.5	-1.4	0.5	0.2	1.5	1.4	1.8	1.1	2.1	0.6	0.3	1.1	0.1	1.5	1.3	0.4	1.5	1.8	-0.2
Alzheimer’s Disease (including proxy)	1.2	1.7	5.0	1.0	1.5	1.8	2.0	1.7	0.0	0.9	1.5	0.1	1.7	2.2	0.8	1.6	1.4	1.1	1.0	-0.3	1.2	0.6	1.0	1.8	1.6	0.4
Ever used hormone-replacement therapy (HRT)	1.2	1.5	6.4	-1.1	-0.5	-0.8	-1.5	-2.1	-0.6	-0.8	-2.5	0.2	0.8	-0.9	-0.6	-0.6	0.2	0.9	-1.3	-1.6	-1.1	-1.3	-0.1	-1.5	1.8	-1.8
Townsend deprivation index at recruitment	1.2	1.7	5.6	-1.1	-1.4	-0.8	-1.3	-1.9	-1.0	-1.2	-1.2	-1.0	-0.1	-1.2	-1.0	-1.7	-0.9	-0.2	-1.4	-1.8	-1.8	-2.4	-1.1	-2.0	0.0	-1.3
Father’s age at death	1.2	1.7	6.4	2.4	1.3	-0.2	0.0	2.4	0.5	0.6	0.4	-1.4	0.7	0.7	0.4	-0.7	2.5	1.6	1.8	0.5	0.2	1.9	1.7	0.7	-0.9	1.2
Prospective memory result	1.2	1.5	4.5	0.6	0.8	1.2	1.5	1.4	0.3	2.1	1.5	-0.4	0.1	1.4	1.9	1.5	-0.2	0.4	0.4	1.7	1.9	1.6	1.3	1.2	-0.0	1.1
Peak expiratory flow (PEF)	1.2	2.9	7.8	-0.8	2.7	2.2	2.8	1.8	0.5	1.8	2.6	0.0	2.2	2.1	0.6	1.6	1.7	2.7	-0.4	0.2	1.0	0.5	1.2	2.4	1.5	1.0
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	10.7	1.2	-1.6	-2.2	-1.8	0.4	1.0	-1.6	-0.3	0.4	-2.6	-1.3	-1.4	-1.6	0.4	-1.3	-0.4	1.3	-0.9	0.4	-1.0	-0.1	-3.3	0.9
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.9	0.9	1.1	1.3	1.0	1.4	-1.3	1.2	1.5	0.8	-0.6	0.5	2.0	1.4	-1.0	-1.1	0.5	1.6	1.8	1.0	1.1	1.2	0.1	1.8
Whole body fat mass	1.2	5.2	20.2	-4.5	-0.9	2.6	1.1	-2.8	-2.5	-0.6	0.1	0.1	1.2	-0.3	0.3	2.8	-2.8	0.9	-3.6	-1.6	-0.4	-3.8	-2.0	-1.9	4.1	-3.0
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	5.2	0.4	1.3	0.5	-0.1	1.4	2.3	1.1	0.5	-0.3	1.1	0.6	0.1	-0.1	2.1	1.9	1.2	0.3	-0.0	1.5	2.1	0.6	-0.5	1.3
Arm fat mass (left)	1.2	4.8	17.6	-4.2	-0.7	2.6	1.1	-2.7	-1.7	-0.3	0.6	0.0	1.0	-0.1	0.6	2.9	-2.8	1.1	-3.7	-1.2	-0.1	-3.7	-2.2	-1.7	3.9	-2.9
Eye problems/disorders: Glaucoma	1.2	1.4	5.7	1.4	-0.3	-1.0	-0.8	-0.3	-1.2	-1.6	1.0	-0.4	-2.2	-1.3	1.1	-0.8	-0.2	-2.1	1.0	2.4	0.7	-0.0	-0.2	-0.1	-1.6	1.0
Crohns Disease (2012)	1.1	1.7	5.8	0.9	-1.1	-1.1	-1.2	-1.0	-0.5	-1.2	-1.8	-0.7	-0.6	-2.3	-2.0	-2.1	0.1	-0.7	-1.3	-1.0	-2.4	-0.7	-0.5	-1.9	-1.1	-1.2
Relative age voice broke	1.1	1.7	6.1	2.5	0.6	-0.2	1.1	2.0	0.7	0.6	1.3	-0.2	-0.1	0.2	0.1	-1.0	2.0	-0.7	1.8	1.3	0.3	2.4	1.5	1.2	-2.1	1.7
Chronic bronchitis/emphysema (father)	1.1	1.3	12.2	-0.7	-1.2	1.0	0.2	-0.4	-3.5	-1.1	-0.3	-1.0	0.5	0.1	-0.0	0.7	-2.6	-0.5	-1.7	-0.8	-0.1	-0.8	-0.2	-0.3	0.9	-0.3
Trunk fat mass	1.1	4.9	18.7	-4.3	-0.7	2.5	1.1	-2.6	-2.6	-0.5	0.0	0.3	1.4	-0.2	0.4	2.8	-2.7	0.9	-3.3	-1.6	-0.4	-3.7	-1.9	-1.8	4.1	-2.8
Waist circumference	1.1	3.9	12.7	-3.4	-1.0	2.2	0.3	-2.5	-1.2	-0.8	0.2	-0.0	0.6	-0.8	0.6	2.3	-2.9	0.9	-3.5	-1.1	-0.3	-3.5	-2.1	-1.8	3.6	-2.5
Arm fat mass (right)	1.1	4.6	16.9	-4.1	-0.7	2.6	1.1	-2.5	-1.7	-0.3	0.7	-0.1	1.0	0.0	0.4	2.7	-2.8	1.3	-3.8	-1.4	-0.1	-3.6	-2.1	-1.5	3.7	-2.7
Shortness of breath walking on level ground	1.1	1.4	5.3	-1.1	-0.7	0.4	1.4	-0.7	-1.7	-0.2	0.1	2.3	0.5	0.0	1.2	1.6	-2.0	0.8	-2.0	-0.5	0.6	-0.9	-0.2	-1.1	1.7	-1.2
Mean time to correctly identify matches	1.1	2.1	11.8	-0.5	-0.8	-1.0	-1.1	-2.4	-2.5	-0.9	-1.0	1.2	-1.2	-0.8	1.4	0.6	-3.4	-2.5	0.8	0.1	0.6	-1.5	-1.4	-1.5	1.0	-1.1
Supplements: Vitamin C	1.1	1.3	4.4	-0.3	-1.4	-1.2	-1.0	-0.2	-0.5	-1.3	-0.5	-1.6	-1.0	-1.6	-1.4	-2.1	0.1	-0.1	-1.4	-0.8	-1.8	-1.0	-0.6	-1.3	-1.5	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	5.3	-2.0	-0.5	-0.4	-0.3	-2.3	0.2	0.5	-0.4	1.2	-0.5	-0.4	0.7	0.3	-0.6	0.3	-1.2	-0.5	0.1	-1.8	-1.1	-2.2	1.2	-1.9
Average weekly red wine intake	1.1	1.6	6.9	-0.0	2.1	1.2	1.0	2.0	1.9	1.4	1.6	-0.1	1.2	1.0	0.0	0.3	2.6	1.2	1.0	0.5	0.3	1.2	1.7	1.2	-0.2	1.1
Age started oral contraceptive pill	1.1	1.4	7.8	0.9	1.7	-0.1	0.3	1.6	0.3	0.2	0.3	0.3	0.7	1.0	0.4	0.6	1.8	-0.3	2.8	1.0	1.0	1.9	1.8	1.6	-0.3	1.4
Fasting Glucose	1.0	1.2	5.6	-0.5	0.8	1.5	1.6	0.6	-0.2	2.4	1.3	-1.0	0.7	0.9	1.0	0.6	1.3	0.6	0.7	0.8	0.7	1.2	1.9	1.1	-0.3	1.8
Allergy or Eczema	1.0	2.7	6.2	1.9	1.5	0.7	1.8	1.6	-0.6	1.1	1.7	0.2	-1.3	1.7	1.9	1.6	0.7	-0.8	2.4	2.5	2.4	2.3	0.9	2.1	-1.2	2.5
Relative age of first facial hair	1.0	2.0	8.7	0.7	1.4	0.1	0.2	1.7	1.4	1.7	0.8	0.5	0.7	0.6	1.4	0.1	2.0	0.5	2.2	1.5	1.1	2.4	2.9	1.4	-0.5	2.3
Hayfever, allergic rhinitis or eczema	1.0	2.1	6.2	2.2	0.6	0.2	1.6	1.4	-0.2	0.8	1.9	-0.4	-1.5	1.2	1.7	1.3	0.3	-0.7	2.0	2.5	2.1	1.9	0.4	1.7	-1.3	2.2
Stomach or abdominal pain in last month	1.0	1.3	3.9	0.2	-1.3	-0.9	-0.5	-2.0	-1.3	0.4	-0.9	1.0	-2.0	-1.2	1.5	-0.3	-1.9	-1.5	-1.4	1.1	0.8	-0.6	-1.2	-1.2	-0.3	-0.2
Sitting height	1.0	7.3	26.3	-0.1	4.5	2.9	3.3	3.3	0.5	2.6	3.8	1.2	2.6	4.4	1.0	2.6	2.1	2.7	1.3	1.0	2.5	1.6	1.9	5.1	1.5	3.6
High blood pressure (mother)	1.0	1.4	4.8	-1.5	-1.5	-1.6	-1.4	-1.0	-0.1	-1.3	-2.2	0.6	-0.4	-0.9	-1.3	-0.5	-1.2	0.1	-1.8	-1.6	-1.2	-0.8	-1.0	-1.4	0.3	-1.7
Alcohol intake versus 10 years previously	1.0	1.4	6.9	-0.5	-1.1	-1.8	-1.9	-1.2	-1.3	-1.9	-0.7	-0.9	-1.6	-1.2	-0.5	-0.6	-2.6	-0.8	-1.5	0.0	-0.4	-1.0	-1.5	-0.6	-0.7	0.0
Noisy workplace	1.0	1.3	5.1	-1.8	-1.3	-0.2	-0.7	-1.6	-1.8	-0.8	-1.0	-0.2	0.1	-1.1	0.7	1.0	-2.3	0.1	-1.3	-1.0	-0.3	-0.9	0.3	-1.6	1.3	-1.1
Pulse wave reflection index	1.0	1.2	3.4	1.8	1.5	-0.7	-0.1	1.8	0.7	0.2	1.1	1.2	-0.6	0.8	-0.4	-0.6	1.3	0.7	1.2	0.7	0.5	1.5	0.4	1.8	-1.6	1.7
Chronic bronchitis/emphysema (mother)	1.0	1.2	6.7	2.0	0.1	-1.3	0.5	0.6	0.8	0.4	0.9	-0.1	-1.6	-0.9	-0.1	-1.8	1.1	-1.5	0.2	1.1	-0.4	1.0	0.4	-0.3	-2.6	1.2
Forced vital capacity (FVC), Best measure	1.0	3.7	8.9	0.4	3.0	2.0	2.6	2.5	-1.0	1.8	2.0	-1.0	2.6	2.2	1.0	1.2	2.3	2.0	2.2	0.4	1.2	2.0	2.8	2.7	1.0	2.0
Osteoarthritis (self-reported)	1.0	1.3	3.1	1.3	1.0	0.4	1.7	1.6	-1.5	0.4	1.6	-0.3	0.7	0.9	0.9	0.8	1.2	0.3	1.7	1.2	1.1	1.7	1.8	1.1	0.0	1.3
Illnesses of father: None of the above (group 1)	1.0	1.3	4.5	-0.4	-0.7	-2.1	-1.5	-1.4	1.0	-1.2	-0.9	1.5	-0.9	-1.4	-0.2	-1.8	-0.2	0.2	-1.2	-0.0	-0.9	-1.7	-1.0	-1.6	-0.6	-0.4
Wears glasses or contact lenses	1.0	1.2	3.1	1.7	-1.8	-1.4	-1.0	0.2	-1.8	-0.3	-0.7	-0.7	-1.2	-1.4	0.5	-0.3	-1.0	-1.6	1.1	1.3	0.0	1.0	0.5	-0.5	-1.4	0.9
HbA1C	0.9	1.0	3.8	-1.3	-1.3	-0.2	-1.2	-2.0	0.4	-0.0	-0.4	-1.5	-0.7	-1.3	0.6	-0.2	-1.0	-0.8	-0.7	0.7	-0.5	-1.8	-1.1	-1.7	0.3	-0.6
Ulcerative Colitis	0.9	1.3	5.8	2.1	0.4	-1.8	-1.4	1.1	2.4	0.4	-0.3	-0.4	-0.8	-0.6	-0.1	-1.3	0.3	-0.4	0.6	0.6	-0.2	1.5	1.0	-0.1	-2.1	1.4
Medication: Metformin	0.9	1.3	5.1	0.1	1.2	1.1	0.6	0.8	1.3	1.4	1.6	-1.2	0.2	1.4	0.8	1.0	0.6	-0.6	0.7	1.3	1.4	1.3	1.0	2.2	-0.1	2.2
Leg fat-free mass (left)	0.9	4.5	14.5	-1.3	2.7	3.8	3.6	1.3	-0.1	1.4	3.8	0.2	2.1	3.2	0.9	3.1	0.2	3.1	-1.1	0.4	1.8	-0.6	-0.1	2.8	2.4	0.8
Qualifications: CSEs or equivalent	0.9	1.2	4.5	-0.3	-2.1	-0.3	-0.7	-0.1	-1.4	-1.1	-1.3	-1.2	-0.4	-1.3	-1.2	-1.2	-0.9	-0.7	-1.6	-1.4	-1.8	0.0	-0.3	-1.0	-1.4	-0.2
Medication: Atenolol	0.9	1.1	3.6	-1.5	1.2	1.5	0.8	0.1	0.1	1.3	0.5	1.4	1.6	1.1	0.6	1.3	1.7	1.4	1.0	0.1	0.7	-0.2	0.6	0.6	1.9	-0.2
Leg predicted mass (left)	0.9	4.7	15.0	-1.4	2.7	3.8	3.6	1.5	0.0	1.5	3.9	0.1	2.1	3.3	1.0	3.2	0.1	3.2	-1.1	0.4	1.9	-0.6	-0.1	2.9	2.5	0.9
Medication: Cholesterol lowering	0.9	1.5	7.0	-0.9	1.4	1.4	1.4	0.4	-0.6	2.0	0.2	-1.1	2.6	1.1	0.5	0.4	1.4	1.6	0.6	-1.2	0.1	0.5	1.9	0.2	1.9	-0.4
Standing height	0.9	8.5	26.7	1.7	4.1	2.6	4.0	4.2	-0.4	3.2	3.5	0.7	2.8	4.2	1.3	2.0	2.9	2.3	3.1	1.5	2.5	3.2	3.0	5.2	0.7	3.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	5.2	0.2	-1.5	-2.3	-1.0	-1.2	-0.7	-1.2	-0.5	0.6	-1.4	-1.8	-0.5	-1.4	-1.0	-1.1	-0.6	0.7	-0.5	-0.6	-0.9	0.0	-1.1	0.4
Pulse rate, automated reading	0.9	2.8	7.1	-1.5	-2.5	-1.4	-2.0	-2.6	-0.2	-1.1	-2.1	2.4	-1.8	-2.1	0.5	-0.7	-2.7	-1.4	-1.9	-0.1	-0.6	-2.0	-1.5	-2.5	0.0	-1.0
Chest pain or discomfort	0.9	1.3	7.8	0.3	-1.2	0.1	-0.3	-1.4	-2.7	-0.3	-0.6	2.0	-1.3	-0.5	1.6	0.5	-2.8	-0.6	-0.5	0.3	0.9	-0.6	-1.0	-0.8	0.5	-0.4
Had major operations	0.9	1.0	3.4	1.9	-0.5	-0.8	-1.0	1.0	-0.8	-0.5	-0.1	-1.2	-0.4	-1.3	-0.3	-1.4	-0.2	-1.4	0.8	0.5	-0.6	1.2	1.3	0.1	-1.7	1.5
Diabetes diagnosed by doctor	0.9	1.5	3.8	-1.1	1.6	1.7	1.3	0.7	0.6	1.8	1.5	-0.7	0.7	1.4	1.5	2.0	0.3	-0.7	1.1	0.9	1.6	0.8	1.4	1.5	1.2	1.4
Medication: Lisinopril	0.9	1.1	7.9	-0.2	1.3	0.8	0.9	1.2	2.8	1.0	1.3	1.0	0.5	0.8	0.9	1.3	1.6	1.2	1.0	0.3	0.9	0.5	0.8	0.4	0.9	0.0
Ever had prostate specific antigen (PSA) test	0.9	1.1	4.5	1.3	0.1	-0.6	-0.8	0.1	2.1	0.1	-0.4	0.2	-1.1	-1.2	-0.9	-2.0	1.5	-1.6	0.4	0.2	-1.0	0.6	0.0	-0.3	-1.9	0.5
Unable to work because of sickness or disability	0.9	1.2	4.1	-1.1	-1.8	0.1	-0.7	-1.0	-1.4	0.0	-2.0	0.4	0.3	-1.0	-0.5	-0.4	-0.8	0.6	-1.3	-1.9	-1.4	-1.2	0.4	-2.0	0.5	-1.0
Supplements: Calcium	0.9	1.0	7.5	-0.3	-1.3	-0.8	-0.8	-0.2	-2.7	-1.7	-1.2	-0.5	0.2	-1.2	-0.9	-1.1	-0.7	-0.9	-0.1	-1.1	-1.1	-0.5	-0.2	-1.1	0.1	-0.9
Age at First Birth	0.8	1.2	4.5	1.6	0.7	-1.2	-0.6	0.3	1.8	0.1	0.7	2.1	-1.6	0.2	-0.6	-1.2	0.7	-0.3	0.7	0.8	0.3	0.2	-1.4	1.0	-2.0	1.0
Body Mass Index (BMI) (2010)	0.8	1.1	4.4	-2.1	-0.6	-0.3	-1.0	-1.6	-0.5	-0.9	-0.8	0.3	-0.2	-0.9	-0.2	-0.0	-1.7	-0.9	-1.4	-0.7	-0.6	-2.0	-1.1	-1.5	0.9	-1.2
LDL Cholesterol	0.8	1.2	5.0	-1.4	1.6	1.8	0.5	0.5	-0.6	-0.3	0.3	-2.0	2.2	1.3	-0.4	0.6	0.8	1.3	0.6	-1.4	-0.5	-0.8	0.4	0.1	1.6	-0.6
Blood White Count	0.8	5.9	23.4	-4.8	-0.8	0.4	-2.4	-2.7	-2.4	-2.1	-3.6	-2.6	1.5	-1.6	-0.4	-0.0	-3.5	-1.4	-2.8	-3.1	-1.9	-3.1	-0.4	-2.9	3.2	-2.5
Supplements: Glucosamine	0.8	1.1	7.0	0.5	0.6	-0.8	-0.4	1.5	1.5	-0.5	0.8	0.2	0.4	0.2	-1.5	-1.6	2.6	1.3	1.1	-0.2	-0.8	0.8	0.9	0.5	-1.3	0.6
Medication: Levothyroxine sodium	0.8	1.4	4.7	-1.8	1.2	1.7	0.5	-0.2	0.0	2.1	0.7	-0.1	1.8	0.8	1.0	1.3	1.0	2.2	0.1	0.2	0.8	0.2	2.0	0.8	1.8	0.7
Forced vital capacity (FVC)	0.8	3.2	7.6	-0.0	2.8	2.2	2.4	2.4	-0.4	2.0	1.5	-0.6	2.2	2.2	1.3	1.5	1.7	1.4	2.0	0.4	1.5	2.1	2.7	2.4	1.2	1.8
Weight	0.8	4.0	15.1	-3.5	0.8	3.5	2.3	-1.1	-1.2	0.6	1.8	-0.0	1.8	1.4	0.6	3.3	-1.8	2.1	-2.8	-0.9	0.6	-2.7	-1.4	0.3	3.9	-1.4
Trunk fat-free mass	0.8	4.4	12.5	-1.1	3.0	3.5	3.0	1.7	1.2	1.9	3.3	-0.5	2.2	3.3	0.7	2.8	0.9	3.2	-0.3	0.4	1.7	-0.2	0.1	3.4	2.3	1.2
Falls in the last year	0.8	1.1	5.4	-0.8	0.1	-0.1	1.2	0.7	0.7	-0.0	1.3	0.5	1.0	0.3	-2.3	-0.9	2.3	1.9	-1.1	-1.0	-1.3	-0.4	-0.1	0.4	-0.4	0.0
Pulse rate	0.8	1.3	4.4	-1.0	-1.4	-0.5	-0.5	-2.0	-0.6	-0.5	-0.9	1.2	-0.7	-1.5	1.7	0.5	-2.1	-1.2	-0.6	0.7	0.5	-1.3	-0.1	-1.9	1.2	-0.8
Happiness	0.8	1.0	3.2	1.3	1.2	0.3	0.0	1.5	1.0	0.5	1.1	0.1	-0.4	0.6	0.7	0.1	0.3	-0.3	1.8	1.4	1.1	1.3	1.1	1.1	-0.7	1.8
Trunk predicted mass	0.8	4.5	12.5	-1.1	3.0	3.5	3.0	1.7	1.3	2.0	3.3	-0.4	2.2	3.3	0.7	2.7	1.0	3.2	-0.3	0.4	1.7	-0.2	0.2	3.4	2.3	1.2
Wheeze or whistling in the chest in last year	0.8	1.3	4.7	-1.1	-0.8	0.1	-0.5	-1.5	-1.3	-1.5	-0.9	0.0	0.4	-0.8	-0.4	0.3	-0.9	0.5	-1.2	-1.7	-0.7	-2.2	-1.2	-1.6	1.8	-2.0
Number of full sisters	0.8	1.0	4.2	0.2	-0.8	0.6	-1.2	-1.0	0.1	-0.9	-0.7	-2.0	-0.9	-1.3	-0.9	-0.5	-1.1	-1.6	0.4	-1.0	-1.3	-1.2	-1.1	-1.1	-0.4	-0.6
Leg pain on walking	0.8	0.9	7.8	0.3	-1.1	0.9	0.6	-0.1	-2.8	-0.5	1.3	-0.8	-1.0	-0.4	0.6	0.8	-2.1	-0.3	-1.3	0.8	0.3	-0.6	-0.4	-0.0	-0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	6.8	1.8	0.4	0.3	2.6	1.1	-0.4	0.1	2.6	-1.0	0.2	1.0	-1.7	-0.8	1.5	1.2	0.0	0.5	-0.3	0.2	-0.6	2.6	-1.6	1.1
Whole body fat-free mass	0.8	4.6	13.9	-1.2	3.0	3.7	3.2	1.6	0.6	1.7	3.5	-0.4	2.3	3.3	0.7	3.0	0.5	3.2	-0.6	0.3	1.7	-0.4	0.0	3.2	2.5	1.0
Leg fat-free mass (right)	0.8	4.1	12.7	-1.2	2.7	3.6	3.2	1.4	0.0	1.3	3.4	0.1	2.2	3.0	0.8	2.9	0.3	3.0	-0.8	0.2	1.6	-0.4	0.1	2.8	2.5	0.8
Mineral and other dietary supplements	0.8	1.1	11.8	-0.6	-0.8	-0.8	-0.9	-1.6	0.4	-0.2	-0.4	-0.2	-1.1	-0.7	0.8	0.5	-3.4	-0.2	-1.4	0.5	0.3	-1.3	-1.4	-1.0	0.2	-0.3
Medication: Aspirin	0.8	1.0	4.4	-1.6	0.2	1.2	0.7	-1.0	1.1	1.5	0.2	0.5	1.2	0.8	0.6	1.1	-0.5	1.4	-0.8	-0.7	0.6	-0.7	-0.2	-0.2	2.1	-1.5
Whole body water mass	0.8	4.5	13.8	-1.3	2.9	3.7	3.2	1.6	0.6	1.7	3.5	-0.4	2.3	3.3	0.7	3.0	0.6	3.2	-0.7	0.3	1.7	-0.4	0.1	3.1	2.5	1.0
Leg predicted mass (right)	0.8	4.2	12.8	-1.2	2.7	3.6	3.3	1.5	-0.0	1.4	3.5	0.1	2.2	3.1	0.8	3.0	0.2	3.0	-0.7	0.3	1.7	-0.4	0.1	2.9	2.5	0.9
Average weekly champagne plus white wine intake	0.8	1.1	4.7	1.3	1.3	-0.4	1.3	0.8	1.7	0.9	0.8	1.6	0.2	0.5	0.6	0.4	2.2	0.6	1.3	1.3	0.9	1.4	1.1	1.0	0.1	0.6
Financial situation satisfaction	0.8	1.0	3.1	-0.8	1.5	1.8	0.7	1.0	0.4	1.1	1.5	-1.3	1.1	1.5	-0.5	1.1	0.2	1.5	-0.1	-0.5	0.3	-0.5	0.7	1.4	1.0	0.8
Medication: Bendroflumethiazide	0.8	1.2	5.7	-1.9	0.3	1.3	0.8	-0.3	0.6	0.5	0.5	0.2	1.5	0.8	-0.8	1.2	0.6	2.4	-1.3	-1.3	-0.4	-1.1	-0.7	0.1	1.9	-1.5
Basal metabolic rate	0.8	4.2	14.4	-1.9	2.4	3.8	3.2	0.9	0.0	1.5	3.1	-0.2	2.2	2.9	0.8	3.2	0.0	3.0	-1.2	0.0	1.5	-1.0	-0.3	2.5	3.0	0.4
Number of operations (self-reported)	0.8	1.2	5.6	1.9	0.1	0.5	0.5	1.1	-1.4	1.0	0.3	-0.8	0.3	0.0	1.5	0.2	0.1	-0.4	1.0	1.1	1.1	1.9	2.4	0.7	-0.6	1.8
Ever depressed for a whole week	0.8	0.9	3.7	0.6	0.0	0.1	1.5	1.9	0.1	0.7	0.9	1.3	-0.4	0.5	0.2	-0.5	1.3	1.1	-0.4	0.5	-0.0	1.3	1.2	-0.0	-1.9	1.6
Bipolar Disorder (2011)	0.7	0.7	3.0	-1.0	0.2	0.9	-0.2	-1.1	1.5	0.1	0.0	-0.6	0.3	0.3	-0.6	0.0	0.5	0.7	-0.2	-0.8	-0.4	-1.3	-1.3	-0.6	1.0	-1.7
Neuroticism (2016)	0.7	1.0	4.4	0.6	-1.0	-1.6	0.2	-0.1	-0.8	0.1	0.2	1.9	-0.8	-1.0	-0.6	-2.1	1.4	-0.4	0.7	0.6	-0.9	-0.3	-0.0	-1.0	-2.0	0.4
Number of treatments/medications taken	0.7	1.2	5.7	-2.4	-0.7	0.4	-0.1	-1.9	0.7	1.5	-0.3	1.0	0.4	-0.4	1.0	1.0	-0.7	1.0	-0.7	-0.2	0.3	-1.6	-0.2	-1.4	2.2	-1.3
Medication for hormone replacement therapy	0.7	0.8	2.5	1.2	0.3	0.0	0.6	1.2	-0.2	0.5	1.0	-0.4	1.0	1.3	-0.4	-0.6	1.6	1.2	0.9	-0.1	0.2	1.1	1.4	1.5	-0.4	1.2
Serious illness, injury or assault to yourself	0.7	0.8	4.5	1.3	0.2	0.6	1.4	1.2	0.1	0.6	1.1	-0.5	0.2	0.7	-0.0	-0.3	2.1	0.2	1.5	0.2	0.3	1.1	1.0	0.9	-0.7	1.3
Impedance of leg (left)	0.7	3.6	16.2	-0.1	-2.7	-2.7	-2.1	-1.9	-2.8	-0.8	-4.0	0.3	-0.8	-2.6	-1.3	-2.3	-0.3	-2.4	0.3	-1.7	-2.1	-0.5	-0.3	-2.5	-0.8	-1.5
Number of incorrect matches in round	0.7	1.1	7.1	0.9	-0.2	0.4	0.7	-1.1	-2.7	0.5	0.1	-0.9	-0.8	-0.3	1.9	0.5	-2.3	-1.5	0.3	1.4	1.0	-0.1	0.2	-0.3	0.1	0.4
Allergy	0.7	1.6	5.7	-1.8	-0.0	0.2	-1.2	-0.5	0.9	0.4	-1.7	0.0	2.0	-0.5	-1.6	-1.3	1.0	1.4	-1.3	-2.4	-2.0	-0.8	0.5	-1.1	1.0	-1.8
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	3.8	-0.3	-2.0	-0.9	0.0	-1.5	-0.9	-0.6	-1.2	0.5	-1.0	-1.8	-1.0	-1.5	0.4	-1.0	-0.8	-0.4	-1.4	-0.8	-0.6	-1.9	-1.1	-0.8
Birth weight of first child	0.7	1.3	4.9	1.1	0.1	1.4	1.5	0.7	-0.2	0.4	1.4	1.1	-0.3	1.5	1.0	1.1	0.0	-0.0	1.3	1.2	1.7	1.4	0.3	2.2	-0.5	1.7
Number of full brothers	0.7	0.9	2.5	1.4	0.2	0.7	1.5	0.2	-0.2	1.1	1.2	-1.3	-0.2	0.9	1.6	0.7	0.0	0.0	0.3	1.0	1.5	1.1	0.6	1.4	-0.1	1.0
Number of children fathered	0.7	0.8	10.3	0.4	-0.0	0.3	-0.6	0.5	0.4	-0.8	0.1	-3.2	0.7	0.4	-1.3	0.4	-0.8	-0.3	-0.5	-0.9	-0.7	-0.4	-0.7	0.4	0.3	-0.8
Emphysema/chronic bronchitis	0.7	0.8	3.3	0.4	-1.4	-0.3	-0.6	-0.6	-1.8	-1.8	-1.1	-0.5	-0.1	-1.2	-0.3	-0.9	-1.1	-1.1	-0.1	-0.5	-1.0	-0.6	-0.5	-1.0	-0.0	-0.7
Illnesses of father: Heart disease	0.7	1.0	3.8	0.4	0.5	1.3	1.6	1.0	0.5	1.1	-0.2	0.6	0.3	0.9	-0.3	0.7	1.3	-0.9	1.5	0.2	0.4	1.9	1.2	1.6	-0.6	1.1
Arm fat-free mass (left)	0.7	3.4	11.8	-1.7	2.2	3.4	2.8	0.5	-0.3	1.3	2.7	-0.5	1.7	2.5	0.7	3.0	-0.3	2.6	-1.5	0.0	1.4	-1.2	-0.5	2.3	2.8	0.4
Arm predicted mass (left)	0.7	3.4	12.8	-1.5	2.0	3.6	2.9	0.5	-0.0	1.3	2.9	-0.3	1.7	2.5	0.8	3.0	-0.1	2.6	-1.6	0.1	1.5	-1.1	-0.6	2.3	2.7	0.3
Ulcerative Colitis (UC)	0.6	1.1	3.6	1.7	0.3	-1.8	-1.5	0.7	1.8	0.3	-0.7	0.5	-1.5	-1.0	0.5	-0.8	-0.6	-0.9	-0.1	1.1	0.2	1.2	0.6	-0.3	-1.9	1.2
Major Depression (MDD)	0.6	0.7	2.5	0.2	0.7	0.7	1.3	0.4	-1.0	1.6	1.0	0.2	0.8	1.3	1.0	0.1	0.1	1.0	0.5	0.4	0.7	0.8	1.0	0.9	-0.3	1.5
Ovarian Cancer	0.6	0.8	2.2	0.4	1.2	1.0	1.3	1.4	-0.6	1.2	0.5	0.2	0.7	1.0	0.2	0.5	1.5	1.4	0.2	0.0	0.4	1.1	1.2	1.0	0.1	0.7
Supplements: Zinc	0.6	0.7	3.0	1.2	0.6	0.1	0.0	1.7	-0.3	0.0	1.3	-0.9	-0.1	0.4	-0.3	-0.5	0.9	-0.7	1.1	0.9	0.0	1.4	0.5	0.8	-1.3	1.0
Medication: Co-codamol	0.6	0.6	2.9	-1.7	-0.8	0.5	-0.0	-0.8	-0.6	-0.1	-0.8	-0.2	0.8	0.2	-0.5	0.1	-1.3	0.9	-1.7	-1.2	-0.4	-0.6	0.2	-0.6	1.0	-0.8
Diabetes (mother)	0.6	0.7	3.3	-1.6	0.8	1.5	-0.2	-0.2	-0.2	0.0	-1.1	-1.2	0.8	0.8	-0.3	1.3	0.1	0.4	0.2	-1.3	-0.1	-0.6	-0.1	0.4	1.8	-0.4
Fed-up feelings	0.6	1.1	5.0	1.8	-1.1	-2.2	-1.2	0.2	0.7	0.2	-0.7	0.2	-1.3	-0.8	-1.2	-1.9	0.4	-0.4	0.5	0.0	-0.7	0.9	0.1	0.2	-2.1	0.8
Financial difficulties in last 2 years	0.6	0.8	3.1	0.9	0.1	1.8	1.5	0.9	-0.7	0.7	1.8	-1.2	0.5	0.9	0.6	1.2	0.3	0.8	-0.7	0.4	0.7	0.0	0.8	0.8	0.2	1.1
Pain all over the body in last month	0.6	0.6	2.3	0.8	-0.4	-1.1	-0.7	1.1	1.5	-0.0	-0.3	-0.4	-0.3	-0.3	-0.8	-0.9	1.5	-0.4	0.4	-0.1	-0.7	0.9	0.7	-0.5	-1.5	0.1
Illnesses of siblings	0.6	0.9	2.7	0.1	-1.2	-1.3	-1.5	-0.8	-0.4	-1.3	-1.0	-1.0	-0.8	-1.4	0.2	-0.6	-1.0	-1.1	0.3	-0.3	-0.6	-0.8	-0.7	-1.6	-0.2	-1.1
Hip circumference	0.6	2.7	12.2	-2.7	0.6	2.7	1.5	-1.3	-1.0	0.4	1.1	-0.3	1.4	0.9	0.7	2.6	-1.8	1.4	-2.0	-1.0	0.5	-2.4	-1.4	-0.4	3.5	-1.8
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	5.6	-0.4	2.0	1.6	1.9	1.9	-0.7	1.5	1.1	-0.3	1.8	1.4	1.1	1.0	1.1	0.9	1.3	0.2	1.0	1.6	2.4	1.9	0.9	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	5.5	0.3	2.1	1.2	2.0	1.8	-1.5	1.2	1.4	-0.8	1.6	1.1	1.3	1.0	1.2	0.6	1.8	0.7	1.0	1.6	2.3	1.8	0.7	1.6
Breastfed as a baby	0.6	0.7	2.7	1.4	0.7	0.1	0.1	0.4	-0.4	-0.8	1.1	0.8	-0.9	0.1	1.5	0.1	-0.2	-0.7	1.1	1.6	1.3	0.1	0.1	0.5	-0.4	1.4
Headache pain in last month	0.6	1.0	5.3	-1.5	0.5	1.1	0.6	-0.6	-1.1	0.9	0.5	0.5	1.1	0.3	1.9	1.1	-0.8	-0.0	1.0	-0.1	0.9	-1.2	0.3	-0.6	2.3	-0.4
Arm fat-free mass (right)	0.6	3.2	11.9	-1.5	2.2	3.4	2.8	0.8	0.1	1.5	2.9	-0.3	1.6	2.4	0.8	2.9	0.1	2.3	-1.0	0.3	1.5	-0.8	-0.4	2.4	2.5	0.5
Eye problems/disorders: None of the above	0.6	0.7	3.8	-0.9	-0.4	-0.6	-0.5	-0.4	0.1	-0.5	-1.3	1.4	0.9	0.0	-1.2	0.2	0.2	0.9	-0.1	-1.9	-0.9	-0.3	-0.5	-0.3	1.3	-1.1
Medication for pain relief, constipation, heartburn	0.6	1.1	4.1	1.0	-0.0	-1.3	-0.8	1.4	0.8	-0.8	0.2	0.6	-0.0	-0.2	-1.6	-1.8	2.0	-0.3	1.4	0.1	-1.0	0.7	0.2	0.7	-2.0	0.6
Arm predicted mass (right)	0.6	3.1	11.9	-1.9	1.9	3.5	2.7	0.4	-0.1	1.3	2.6	-0.3	1.8	2.3	0.5	2.9	-0.0	2.3	-1.4	-0.1	1.2	-1.2	-0.6	2.1	2.7	0.2
Medication: Aspirin	0.6	0.8	3.4	-1.4	0.4	1.1	0.5	-0.9	1.1	1.4	0.2	0.4	0.8	0.9	0.9	1.3	-0.9	1.0	-0.7	-0.2	0.9	-0.3	-0.2	0.1	1.8	-0.9
Back pain experienced in last month	0.6	0.9	3.9	0.3	-0.8	0.3	0.8	-0.4	-1.7	0.5	0.8	0.8	-1.1	0.3	1.3	1.1	-2.0	0.0	-1.1	1.4	1.5	0.4	-0.1	1.1	-0.2	1.0
Number of self-reported non-cancer illnesses	0.6	1.0	6.7	-2.6	-0.2	0.4	0.2	-1.6	-0.5	0.6	-0.8	1.1	0.7	-1.1	0.3	0.2	0.5	0.4	0.0	-0.7	-0.5	-1.4	0.2	-1.8	1.7	-1.0
Miserableness	0.6	1.1	3.2	0.3	-1.8	-1.8	-0.8	-1.4	-0.1	-0.5	-1.8	0.8	-1.3	-1.5	-0.9	-1.1	0.3	0.4	-0.7	-0.5	-1.0	-0.8	-0.9	-1.6	-0.9	-0.8
Guilty feelings	0.6	0.8	2.8	-0.2	-1.7	-1.1	-1.0	-1.0	0.1	-1.1	-0.4	-0.1	-1.6	-1.5	-0.5	-0.8	-0.6	-0.8	-0.4	-0.0	-0.9	-0.9	-0.8	-1.2	-1.3	0.4
Hearing aid user	0.6	0.7	3.4	0.4	1.0	1.3	0.4	0.5	0.4	0.9	0.1	0.0	0.5	0.2	1.4	0.5	0.2	-1.1	1.8	0.5	0.8	1.0	1.4	0.3	0.8	0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	4.1	0.4	-0.5	-0.3	-0.7	0.3	-0.2	-0.9	-0.6	0.1	-0.1	-0.5	-1.8	-1.7	2.0	-0.6	0.3	-1.0	-1.4	0.1	-0.2	-0.4	-1.2	-0.8
Fractured/broken bones in last 5 years	0.6	0.8	5.6	0.3	-1.3	-1.3	-1.5	-0.4	2.4	-0.2	-0.5	0.8	-0.7	-1.0	-0.5	-0.8	-0.2	-0.3	-1.5	-0.1	-0.6	-0.2	-0.4	-0.8	-0.7	-0.7
Mean Putamen Volume	0.5	0.6	2.6	1.1	1.3	0.5	0.9	1.6	-0.1	0.1	1.0	-0.2	1.3	0.8	-0.5	-0.1	0.9	0.4	0.6	-0.1	-0.1	0.9	1.0	0.9	-0.2	0.5
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.0	1.7	0.4	0.4	0.9	1.0	-0.8	0.5	0.5	0.7	-0.4	0.0	0.1	-1.1	1.1	-0.5	0.5	0.3	-0.2	1.0	1.0	0.5	-1.7	1.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	5.0	-0.8	-0.2	-0.3	0.5	0.3	-2.2	-1.1	-0.1	1.7	0.3	-1.1	-0.4	-1.0	0.2	-1.1	0.3	-0.6	-0.9	-0.6	0.5	-1.0	-0.0	-0.2
Vitamin and mineral supplements	0.5	0.7	4.5	-0.9	-0.6	-0.7	-0.9	-2.1	-0.3	-0.4	-1.1	-0.6	0.2	-0.4	0.1	0.5	-1.0	0.3	-0.2	-0.6	-0.3	-1.0	-0.5	-1.0	1.2	-1.4
Hand grip strength (right)	0.5	1.5	5.8	0.3	1.8	1.6	1.1	1.9	-0.0	0.9	1.3	-1.7	1.6	1.6	-0.0	1.2	0.4	0.9	0.2	0.0	0.7	1.3	1.2	2.4	0.6	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	6.7	-2.6	0.4	0.8	-0.3	-0.4	0.5	-0.4	0.4	-1.0	1.6	0.4	-0.2	0.8	-0.9	1.4	-0.2	-1.0	-0.3	-1.8	-0.3	-0.1	2.4	-0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.0	0.3	-0.0	1.3	0.9	0.1	-0.5	0.9	0.8	-1.4	0.8	0.3	1.2	0.5	0.2	-0.5	1.1	0.0	0.7	0.1	0.6	0.2	0.9	0.3
Past tobacco smoking	0.5	0.9	4.8	0.4	-0.0	0.3	0.2	0.9	1.6	0.5	0.4	-1.2	0.2	0.5	-2.2	-0.5	2.1	0.5	1.4	-0.7	-1.0	0.4	-0.5	0.9	-0.9	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	8.6	-2.9	0.4	1.0	-0.1	-0.3	1.1	-0.2	0.8	-1.0	1.6	0.2	0.0	0.7	-0.4	1.4	-0.1	-0.7	-0.4	-1.7	0.2	-0.3	1.9	-0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.6	0.3	-0.8	-0.2	0.7	0.7	-0.8	-0.5	-0.0	1.2	-0.8	-0.5	0.1	-0.3	0.0	0.7	-1.6	0.5	-0.5	0.7	0.9	-0.5	-1.6	1.2
Medication: Simvastatin	0.5	0.8	4.9	-2.2	0.2	0.6	-0.2	-1.0	-0.8	0.6	-0.6	-0.6	0.8	0.1	-0.7	0.1	-0.7	0.2	-1.1	-1.6	-0.8	-1.1	-0.5	-1.1	0.9	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.0	0.5	0.8	-1.1	0.1	1.0	-0.2	-0.5	0.4	1.4	-0.1	-0.3	-0.2	-0.6	1.0	-0.2	0.4	0.5	-0.2	0.8	1.0	0.2	-1.3	1.3
Blood clot in the leg (DVT)	0.5	0.6	3.4	-0.3	-0.5	-1.2	0.3	-1.2	-0.7	-0.4	0.4	0.6	-0.5	-0.4	-0.0	-0.2	-1.8	-0.0	-0.7	-0.1	-0.1	-1.2	-1.1	-1.1	0.2	-1.0
High blood pressure (siblings)	0.5	0.7	2.1	-0.0	0.5	1.4	1.3	0.7	-0.2	1.3	0.8	1.2	0.6	0.9	0.2	0.4	0.8	1.3	-0.7	0.2	0.5	0.8	0.8	1.2	0.2	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.9	-0.9	0.6	1.7	0.8	0.0	-1.0	0.7	0.3	-0.9	0.6	0.6	1.0	1.6	-0.2	1.1	-1.6	0.3	0.5	-0.4	0.4	0.1	0.8	0.4
Overall health rating	0.5	1.0	3.5	-1.6	-0.2	1.1	1.0	-1.4	-1.9	1.4	-0.1	0.2	0.3	0.2	1.3	1.2	-1.6	0.1	-0.9	-0.1	0.7	-1.0	0.2	-0.8	1.6	-0.4
Hypertension (Self-reported)	0.5	1.4	7.5	-2.7	-0.2	1.2	-0.1	-1.0	-0.1	0.5	-0.5	-0.9	1.8	-0.9	-0.1	0.8	-0.1	1.2	-1.5	-1.1	-0.9	-1.5	0.5	-1.3	2.2	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.2	-0.2	0.2	0.2	-0.2	-1.1	-0.9	-1.1	-1.5	0.7	-0.2	-0.6	0.5	0.8	-1.4	-0.6	-0.9	-0.7	-0.0	-0.6	-0.3	-1.0	1.2	-0.8
Mother’s age at death	0.5	0.6	4.3	0.8	-0.4	-0.6	-0.2	0.1	0.7	0.3	-0.5	2.1	-1.6	0.0	0.5	0.1	-0.2	-0.7	0.7	1.4	0.9	0.5	-0.6	0.4	-1.0	0.8
High cholesterol (Self-reported)	0.5	0.9	3.4	-1.7	1.6	1.1	-0.1	-0.3	-0.5	1.0	-1.2	-1.0	1.7	0.8	0.2	0.6	-0.3	-0.1	0.2	-1.4	-0.2	-0.3	0.8	-0.2	1.9	-0.8
Medication: Atorvastatin	0.5	0.6	3.7	-0.7	1.0	0.7	0.3	0.3	1.9	0.6	0.4	-0.0	1.0	0.3	-0.4	1.1	0.7	1.3	-0.2	-0.4	-0.1	0.0	0.3	0.8	1.5	-0.3
Illnesses of father: High blood pressure	0.5	0.6	4.1	0.5	-0.5	-0.5	0.6	0.7	-0.8	-0.5	0.1	-1.0	0.4	-0.3	-2.0	-0.8	0.3	0.4	-0.2	-1.7	-1.2	0.3	-0.2	-0.1	-0.5	-0.9
Alcohol drinker status: Never	0.5	0.6	4.9	-2.2	-1.1	-0.0	-0.4	-0.5	0.0	-0.5	0.6	0.7	-0.2	-0.6	-0.7	0.0	-0.9	0.6	-1.8	-0.3	-0.7	-1.1	-0.4	-0.6	-0.3	-0.2
Ever smoked	0.5	0.9	5.6	0.1	0.7	0.4	0.4	0.1	-2.1	-0.3	0.1	0.2	0.2	0.1	2.4	1.0	-1.8	-0.4	-1.1	0.8	1.3	-0.0	1.2	-0.3	1.0	0.8
Cholesterol lowering medication	0.5	0.8	4.5	-1.7	1.6	0.9	-0.1	-0.1	0.1	0.6	0.2	0.1	-0.1	0.8	0.9	2.1	-1.3	-0.2	0.1	0.7	1.2	-0.3	-0.4	0.2	1.3	-0.2
Bipolar Disorder (2018)	0.4	0.7	1.7	-0.4	-1.2	-0.8	-1.0	-1.2	1.2	-0.0	-0.4	-0.4	-0.5	-0.6	-1.2	-1.3	-0.0	-0.4	-0.3	-0.6	-1.0	-1.0	-1.2	-0.7	-0.8	-0.7
Depression (Nagel 2018)	0.4	0.7	3.0	1.1	-0.5	-0.2	-0.1	-0.0	-0.9	-0.1	-0.2	1.3	-1.3	-1.2	0.2	-1.2	1.0	-1.3	0.2	0.4	-0.5	0.5	0.2	-0.8	-1.7	0.4
Irritable Bowel Disease (IBD)	0.4	1.1	4.1	1.8	-0.1	-1.7	-1.1	0.4	0.8	0.1	-0.5	0.8	-1.5	-1.7	0.2	-1.0	-0.3	-0.7	-0.5	1.4	-0.3	1.0	0.9	-0.6	-2.0	1.0
Prostate Cancer	0.4	0.5	3.1	0.4	-0.7	0.3	-1.0	0.1	0.3	-0.9	-0.5	-1.7	-0.3	-1.2	-0.5	-0.9	0.1	-0.8	-0.2	-0.3	-1.1	-0.2	0.3	-1.1	-0.9	-0.1
Rheumatoid Arthritis	0.4	0.6	3.5	-1.3	-0.7	0.2	0.3	-0.4	-1.2	-0.7	-0.2	1.9	0.5	-0.6	0.3	0.4	-0.9	0.1	-0.7	-0.9	-0.3	-0.8	-0.0	-0.8	1.2	-0.6
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.9	0.4	0.8	-0.4	0.2	0.6	-0.2	1.0	0.2	0.6	-0.2	0.5	1.4	0.3	0.3	0.2	0.8	1.0	1.0	1.0	0.8	0.7	-0.2	1.0
Blood Red Count	0.4	3.5	10.8	-2.8	-1.1	-1.3	-2.4	-3.3	-1.1	-1.2	-3.1	1.9	-0.9	-2.1	1.2	0.4	-2.0	-2.0	-0.7	-0.3	-0.1	-2.0	-1.8	-2.9	2.0	-2.5
Smoking Status	0.4	1.0	7.3	0.5	1.0	1.0	0.9	0.5	-2.7	0.5	0.5	-1.0	0.8	0.6	1.6	1.3	-0.6	-0.1	-0.5	0.6	1.0	-0.0	1.4	0.2	1.2	1.0
Severe depression (siblings)	0.4	0.5	4.6	-0.3	0.8	-0.1	-0.2	-0.4	0.1	0.3	0.3	2.1	-1.2	0.1	1.0	0.5	-0.5	-1.1	0.1	0.9	0.8	-0.2	-0.6	0.1	-0.1	0.5
Impedance of leg (right)	0.4	1.7	7.9	0.3	-1.9	-2.0	-1.2	-1.2	-2.2	-0.2	-2.8	0.1	-0.6	-1.6	-0.8	-1.7	0.1	-1.7	0.4	-1.0	-1.4	-0.1	-0.1	-1.8	-0.8	-0.9
Current tobacco smoking	0.4	0.6	3.1	0.2	0.7	1.4	0.6	-0.1	-1.8	0.1	-0.3	-1.2	0.4	0.5	0.2	1.4	-1.0	-0.6	-0.6	-0.5	0.1	-1.0	0.0	-0.2	1.4	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.1	0.3	0.5	0.2	0.3	0.5	-1.4	0.5	0.1	0.6	-0.6	-0.6	1.2	0.5	0.4	-1.2	1.0	1.0	0.4	0.5	1.3	-0.7	-0.5	0.9
Hair/balding pattern: Pattern 2	0.4	0.5	2.0	-0.1	0.2	0.8	-0.1	1.0	0.1	1.0	0.4	-1.4	1.1	0.8	-0.6	0.1	0.4	0.1	0.7	-0.9	-0.2	1.2	1.1	1.0	-0.0	0.4
Hair/balding pattern: Pattern 3	0.4	0.6	3.0	-0.4	-0.7	-0.2	0.3	-1.4	-0.9	-0.7	0.7	0.4	-0.6	-0.6	0.5	0.5	-1.0	-0.1	-1.7	0.7	0.4	-0.9	-1.4	-0.2	0.6	-0.6
Asthma	0.4	0.9	3.0	1.3	0.3	0.1	0.8	0.4	-0.5	-1.1	1.1	0.2	-1.2	0.3	1.2	1.4	-1.1	-0.7	0.4	1.5	1.7	0.7	-0.3	1.0	-0.2	1.5
Pulse wave Arterial Stiffness index	0.4	0.5	2.8	-0.6	1.1	0.3	0.1	0.2	0.2	0.3	0.7	1.7	-0.0	0.5	1.2	1.1	-0.3	0.5	0.2	0.6	1.2	0.0	0.4	0.6	1.0	0.6
Tense / ‘highly strung’	0.4	0.7	6.6	-0.9	-0.8	0.3	0.9	-0.5	-2.6	0.2	-0.4	1.3	0.1	-0.4	1.4	0.7	-0.4	-0.6	0.1	0.3	0.6	0.1	1.1	-0.4	0.8	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	3.4	-0.2	0.1	-0.7	-0.3	-0.2	1.0	1.0	-0.2	-0.7	-0.2	0.2	-1.1	-0.8	1.3	1.8	-1.5	-0.4	-1.0	-0.4	-0.4	-0.4	-1.4	0.3
Hair/balding pattern: Pattern 4	0.4	1.1	3.6	1.5	0.1	-0.6	0.1	1.3	1.6	0.5	0.3	1.5	-1.1	-0.1	1.3	0.2	0.7	-0.5	0.9	1.9	1.1	1.6	0.9	0.2	-1.4	1.1
Medication: Paracetamol	0.4	0.6	3.1	0.3	-0.2	1.0	0.0	-0.8	-1.3	-0.5	-0.4	-1.7	-0.1	-0.2	0.9	0.7	-1.8	-0.1	-1.2	-0.5	0.4	-0.6	-0.3	-0.5	1.3	-0.5
Gout (self-reported)	0.4	0.5	4.5	-0.3	0.2	-1.2	-0.8	-0.5	0.5	0.4	0.2	2.1	-0.9	-0.2	-0.0	-1.3	0.4	-0.2	0.1	0.6	0.0	-0.1	-0.3	-0.4	-1.0	0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.2	-1.5	0.3	1.2	0.8	-0.4	-1.1	1.1	0.7	0.1	1.5	0.2	0.3	0.5	1.3	1.8	-0.2	-0.4	-0.0	-0.6	1.1	0.2	1.4	-0.3
Medication: Amlodipine	0.4	0.6	3.1	-1.4	0.3	0.1	-1.0	-0.9	-0.4	0.7	-1.8	-0.5	0.4	-0.2	0.6	0.4	-0.1	-0.7	0.4	-0.4	0.1	-0.3	0.1	-1.1	1.5	-1.1
Exposure to tobacco smoke outside home	0.4	0.5	1.8	-0.5	0.3	0.7	0.8	-1.0	0.6	-0.2	0.1	-0.8	0.6	0.7	-0.6	0.5	0.4	1.2	-0.1	-1.4	-0.3	-0.9	-1.0	-0.2	0.8	-1.2
Worry too long after embarrassment	0.4	0.6	2.8	1.7	0.3	-0.6	-0.2	0.1	0.2	-0.1	-0.1	-1.0	-0.7	-0.1	-0.3	-1.0	1.1	-0.3	1.4	0.0	-0.1	1.3	0.5	0.7	-1.5	1.2
Pulse wave peak to peak time	0.4	0.4	3.4	0.5	-0.9	-0.0	0.0	-0.2	-0.3	-0.3	-0.6	-1.8	0.4	-0.3	-1.2	-1.0	0.4	-0.4	-0.1	-0.7	-1.2	-0.0	-0.3	-0.3	-0.8	-0.6
Neck or shoulder pain in last month	0.4	0.6	4.0	-0.3	-2.0	-0.4	-0.4	-0.9	-1.9	-0.1	-0.9	-0.5	-0.5	-0.4	-0.1	-0.4	-1.5	-0.5	-0.5	-0.5	-0.2	-0.4	-0.3	-0.6	0.0	-0.1
Medication: Blood pressure	0.4	0.7	4.2	-0.3	0.3	1.2	0.7	-1.0	-0.5	0.8	0.6	0.4	0.7	0.3	1.5	1.3	-1.0	0.3	0.2	0.0	1.0	-0.4	-0.1	-0.2	2.0	-0.8
Medication: Seretide 50 evohaler	0.4	0.4	3.9	-0.1	-0.8	-0.2	-0.2	-0.1	0.7	-1.3	-0.2	-0.8	-0.5	0.1	-0.5	-0.1	-1.0	0.6	-2.0	-0.5	-0.1	-0.5	-0.7	0.0	-0.0	0.1
Suffer from ‘nerves’	0.4	0.6	8.5	-0.4	0.6	-0.2	0.6	-0.4	0.4	0.4	0.8	2.9	-0.6	0.1	0.3	0.3	1.0	1.3	0.6	0.7	0.5	-0.7	-0.5	0.3	0.1	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.8	0.4	-0.2	-0.7	0.4	-1.0	-1.4	-0.9	0.7	0.9	-0.7	-0.5	0.3	-0.2	-1.0	-0.6	-0.4	0.6	0.2	-0.9	-1.0	-0.4	0.1	-0.4
Knee pain experienced in last month	0.4	0.6	3.0	0.2	-0.4	0.8	1.6	-0.6	-1.6	0.2	1.6	-1.7	-0.4	0.1	0.4	0.3	-0.8	0.7	-0.8	0.5	0.3	-0.3	-0.4	0.6	-0.4	0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	4.5	-0.4	-0.4	-0.3	-0.4	0.1	2.1	0.1	-0.5	0.6	-0.5	0.1	-1.4	-0.7	0.6	0.1	-0.7	-0.6	-0.6	-0.3	-0.8	0.1	-0.7	-0.1
Long-standing illness, disability or infirmity	0.4	0.6	2.2	-0.3	0.2	0.6	1.0	-0.1	-1.4	0.3	0.3	0.6	1.5	-0.0	-0.2	-0.1	1.3	1.4	-0.0	-0.8	-0.4	-0.7	1.0	-0.3	1.4	-0.5
Medication for cholesterol	0.4	0.6	2.4	1.6	-0.8	-0.9	1.1	0.0	-0.7	-0.6	0.7	1.1	-1.1	-0.4	-0.1	-1.1	0.1	-0.3	-0.2	0.5	-0.1	-0.0	-0.8	0.0	-1.6	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.7	3.5	0.5	0.8	-0.9	0.3	-0.0	-0.1	0.5	0.7	-0.5	-0.5	-0.1	1.9	0.2	0.7	-0.3	1.8	1.6	1.2	1.1	1.1	-0.0	-0.4	1.0
Ever taken oral contraceptive pill	0.4	0.5	2.8	0.7	0.1	-1.0	0.4	-0.1	0.5	0.4	0.5	1.0	-1.0	-0.8	0.9	-0.2	0.6	-0.8	0.4	1.7	0.7	0.5	0.1	0.1	-0.7	0.8
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.7	-1.2	-0.0	-0.7	-0.8	-0.5	0.2	-0.6	-1.3	0.3	-0.6	-1.1	-0.5	-0.7	0.5	-0.7	-0.7	-0.3	-0.9	-0.3	0.2	-0.8	-0.3	0.2
Medication: Blood pressure	0.4	0.7	4.1	-2.0	0.4	0.8	-1.0	-1.0	0.1	0.7	-1.0	-0.8	0.7	-0.1	0.3	1.4	-0.2	0.4	-0.7	-0.4	-0.1	-0.8	-0.1	-0.7	1.7	-1.0
Commuting to job workplace: Cycle	0.4	0.5	3.3	1.0	-0.1	-0.9	-1.1	-0.0	0.6	-0.2	-0.3	-1.8	-0.5	-0.7	0.2	-1.3	-0.3	-1.1	0.0	0.6	-0.0	0.3	0.4	-0.1	-0.8	0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	4.9	1.6	-0.4	-1.5	-0.4	0.3	-0.1	-1.3	-0.1	0.7	-1.7	-0.0	-0.8	-1.5	-0.4	-1.4	0.8	0.3	-0.1	0.5	-0.9	0.5	-2.2	0.7
Pain experienced in last month	0.4	0.7	3.6	-0.3	0.8	-0.6	-0.5	0.9	1.9	-0.4	-0.5	1.1	1.0	0.2	-1.4	-0.5	1.8	0.6	0.5	-0.8	-0.9	0.0	0.3	0.1	0.1	-0.5
Impedance of whole body	0.4	2.2	9.0	1.3	-1.6	-2.8	-1.7	-0.7	-2.1	-0.4	-3.0	0.7	-0.7	-1.8	-0.8	-2.1	0.2	-2.2	1.4	-0.7	-1.3	0.9	0.7	-1.6	-1.5	-0.4
Neuroticism (Nagel 2018)	0.3	0.7	3.0	0.1	-1.7	-1.2	-0.4	-1.3	-0.5	-0.3	-0.4	0.9	-1.4	-1.6	-0.2	-0.7	-0.0	-0.3	-0.3	0.0	-0.6	-0.3	-0.4	-1.2	-0.9	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	1.3	0.6	-0.1	0.2	0.5	0.1	-0.8	-0.3	0.2	0.9	0.1	0.6	0.6	1.0	-0.0	0.1	0.1	-0.2	0.8	-0.1	-0.3	0.1	1.1	-0.9
Breast Cancer	0.3	0.7	3.4	-0.6	-0.7	-0.7	-1.2	0.1	0.3	-0.9	-0.9	-1.8	-0.9	-1.3	0.1	-1.1	-0.4	-0.5	0.5	0.5	-0.6	0.6	0.6	-1.0	-1.2	0.5
Lupus	0.3	0.4	5.0	0.2	0.0	-1.0	-0.4	0.1	1.0	-0.5	0.0	2.2	-0.7	-0.1	0.4	-0.1	0.2	-0.2	0.5	0.5	0.2	0.4	-0.1	-0.3	-0.7	0.3
Blood Eosinophil Count	0.3	2.3	9.2	-1.6	0.7	2.5	1.1	0.9	-1.0	-0.2	0.7	-1.4	2.8	1.4	-1.2	1.6	0.9	3.0	-1.2	-2.2	-0.6	-1.0	0.6	1.2	2.5	-0.4
Blood Platelet Count	0.3	3.4	12.6	-1.0	-2.0	-0.6	-3.1	-2.2	0.0	-2.0	-1.9	-1.3	-2.7	-3.4	0.9	-0.1	-3.5	-3.4	-1.7	0.9	-0.2	-0.7	-0.9	-2.1	-0.2	-0.2
Cardiovascular Disease	0.3	1.0	5.2	-2.3	0.4	0.9	-0.4	-0.6	-1.1	0.6	-1.1	-0.7	1.4	-0.3	-0.2	0.1	-1.1	0.1	-0.7	-1.6	-0.8	-1.2	0.8	-0.8	1.8	-0.6
Hypothyroidism (self reported)	0.3	0.7	3.0	-1.4	0.3	0.8	0.6	-0.7	-1.3	1.7	0.3	0.3	1.2	0.4	0.7	0.4	1.0	1.7	0.2	-0.3	0.2	-0.3	1.0	0.1	1.2	-0.4
Respiratory disease	0.3	0.8	4.4	2.1	-0.1	-0.2	0.6	0.4	-1.1	-1.5	0.9	0.6	-1.1	0.4	0.3	0.4	-0.7	-0.8	0.9	0.8	1.0	0.7	-0.7	1.0	-0.6	0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.7	2.6	-0.6	1.6	1.2	0.3	0.8	0.8	1.0	0.7	-0.5	0.5	1.1	0.4	0.9	0.4	-0.4	0.8	0.1	0.6	0.7	1.0	1.1	0.6	1.1
Lung FEV1/FVC ratio	0.3	1.4	4.8	-0.4	-1.3	-2.2	-1.6	-0.7	0.5	-1.2	-1.5	0.3	-1.2	-1.9	-0.5	-1.6	-0.8	-1.1	-0.8	-0.2	-1.2	-1.0	-0.7	-1.9	-1.0	-0.9
Neuroticism	0.3	0.7	3.4	1.0	-0.7	-1.2	-0.8	-0.6	0.6	-0.2	-0.0	0.7	-1.8	-1.3	0.7	-0.6	0.3	-1.0	1.3	1.1	0.4	0.6	0.1	-0.5	-1.3	0.9
Hearing difficulty/problems: Yes	0.3	0.5	4.2	-0.3	0.5	-0.5	-0.5	0.4	-0.8	-0.7	0.2	0.1	-0.3	-1.1	0.3	-0.1	0.3	-2.0	0.8	0.7	-0.1	0.4	1.3	-0.4	-0.3	0.3
Systolic blood pressure, automated reading	0.3	0.8	4.6	-1.6	-0.9	0.6	-2.1	-0.3	1.6	0.5	-1.4	-0.2	-0.1	-0.8	0.3	0.7	-0.8	-1.6	-0.9	0.5	-0.1	-0.0	0.6	-0.5	0.5	0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.6	-0.8	-0.1	1.2	0.7	-0.5	0.6	0.8	0.8	-0.6	0.2	0.2	0.6	0.4	0.4	-0.5	0.8	0.0	0.3	-0.9	-0.1	-0.3	0.8	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	3.3	0.3	-0.0	-0.4	0.4	0.8	0.7	0.3	0.7	1.8	-0.4	-0.7	0.1	-0.8	1.2	-0.3	0.7	0.3	-0.4	0.3	0.9	-0.1	-1.1	1.3
Hearing difficulty/problems with background noise	0.3	0.4	3.4	-0.2	-0.3	-0.2	-0.3	0.1	-1.9	-0.8	-0.8	0.3	0.7	-0.6	-0.5	-0.3	0.2	-0.4	0.5	-0.9	-0.8	-0.5	0.7	-0.7	0.7	-0.5
Mouth/teeth dental problems	0.3	0.5	2.6	-1.2	-0.4	-0.5	0.1	-0.1	0.9	-0.3	0.4	0.6	0.4	0.3	-0.8	-0.2	1.5	1.6	-0.1	-0.2	-0.2	-0.8	-1.0	0.5	0.2	-0.5
Neuroticism score	0.3	0.6	2.4	0.5	-1.3	-1.2	-0.5	-1.1	-0.0	0.2	-0.6	0.2	-1.6	-1.3	0.1	-0.9	0.0	-0.7	0.5	0.4	-0.2	0.3	-0.3	-0.7	-1.3	0.6
Impedance of arm (right)	0.3	1.2	4.5	1.8	-0.5	-2.1	-0.7	0.6	-1.5	-0.0	-1.6	0.7	-0.0	-0.3	-0.4	-1.7	0.8	-0.8	1.8	-0.4	-0.5	1.7	1.3	-0.3	-1.5	0.5
Worrier / anxious feelings	0.3	0.5	2.7	-0.3	-0.1	-0.7	-0.3	-0.7	0.9	1.1	-0.1	1.6	-0.3	-0.7	0.7	-0.2	1.4	0.5	1.3	0.7	0.3	0.5	0.8	-0.4	-0.1	0.6
Depression (self-reported)	0.3	0.4	2.1	-0.8	0.2	1.5	0.5	-0.9	-0.0	0.3	0.1	0.6	0.3	-0.0	0.4	0.5	-0.2	1.1	-1.1	-0.3	0.0	-0.9	-0.2	-0.5	0.8	-0.3
Impedance of arm (left)	0.3	1.5	5.9	1.5	-1.2	-2.4	-1.3	0.2	-1.3	-0.3	-2.1	0.6	-0.3	-1.0	-0.5	-1.8	0.4	-1.5	1.6	-0.2	-0.8	1.6	1.1	-0.9	-1.7	0.1
Exposure to tobacco smoke at home	0.3	0.4	1.5	1.1	0.1	0.2	0.7	-1.0	-0.2	0.6	1.2	-1.1	-0.8	-0.3	0.8	-0.0	-0.1	-0.5	-0.4	0.9	0.6	-0.3	-0.5	-0.4	-0.1	-0.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.9	-0.3	-0.5	-0.7	-0.2	-0.3	0.1	-1.4	-0.1	1.7	-0.2	-0.8	-0.6	-0.6	-0.0	0.6	-0.8	-0.4	-0.6	-0.8	-0.3	-0.8	-0.3	-0.5
Birth weight	0.3	0.7	3.0	1.4	-0.6	-0.5	0.1	0.0	-0.0	-0.6	1.4	-0.1	-1.4	-0.6	-1.0	-1.0	0.1	-1.0	0.1	0.8	-0.5	-0.1	-1.6	0.6	-1.7	0.2
Medication: Allopurinol	0.3	0.4	3.4	-0.7	0.3	-1.2	-1.0	-0.2	0.0	0.3	-0.2	1.9	-0.1	-0.2	0.4	-1.3	0.1	-0.1	0.3	0.2	0.0	0.0	0.9	-0.2	-0.4	0.8
Smoking status: Previous	0.3	0.5	2.7	-0.1	-0.3	-0.3	0.0	-0.6	-0.6	-0.1	-0.0	1.5	-0.5	-0.2	1.6	0.4	-1.5	0.0	-1.4	0.8	1.0	-0.1	-0.1	-0.2	0.4	0.2
Mood swings	0.3	0.6	1.8	0.5	-0.5	-0.4	0.6	-0.6	-0.9	0.8	0.7	-1.3	-1.1	-1.0	1.2	0.3	-0.9	-0.2	-0.6	1.2	0.6	0.6	0.6	-0.1	-0.9	1.3
Ever had bowel cancer screening	0.3	0.3	2.8	-1.3	0.5	-0.1	-1.0	-0.1	1.7	0.3	-0.0	0.8	-0.1	-0.1	-0.3	-0.1	-0.1	-0.0	-0.2	-0.1	-0.2	-0.4	0.0	-0.3	0.4	-0.0
Friendships satisfaction	0.3	0.4	1.5	0.5	0.9	-0.4	-0.2	1.1	0.9	0.4	0.1	0.4	0.3	0.5	0.0	-0.6	1.1	-0.1	1.2	0.3	0.2	0.7	0.7	0.0	-0.4	0.5
Asthma (self-reported)	0.3	0.7	1.9	1.3	0.2	0.1	0.5	0.2	-0.7	-1.4	0.7	0.2	-1.1	0.2	0.8	1.2	-1.2	-0.7	0.3	1.1	1.4	0.5	-0.5	0.8	-0.2	1.2
Osteoporosis (self-reported)	0.3	0.3	2.5	-0.3	-0.4	-0.8	1.2	-0.4	-1.6	-0.3	0.2	0.7	0.1	-0.6	0.1	-0.0	1.0	0.1	-0.1	0.1	-0.2	0.1	-0.0	-0.5	0.2	-0.8
Medication: Gliclazide	0.3	0.4	2.9	-1.7	0.4	-0.1	0.4	-1.3	0.5	1.2	-0.4	-0.3	-0.3	0.6	0.1	0.6	-0.1	-0.6	-0.3	0.2	0.6	-0.3	-0.2	0.5	0.7	0.2
Smoking status: Current	0.3	0.5	3.0	0.0	0.8	1.1	0.4	-0.4	-1.7	-0.1	-0.4	-1.0	0.5	0.4	-0.2	1.0	-0.8	-0.6	-0.4	-0.8	-0.1	-1.1	0.0	-0.4	1.3	-0.2
Pain type(s) experienced in last month: Hip pain	0.3	0.4	4.7	0.5	0.1	0.1	0.7	0.4	-2.2	-0.2	0.5	0.3	0.4	0.0	0.7	-0.4	-0.3	0.1	-0.9	0.5	0.2	0.9	1.0	0.3	-0.5	0.4
Average weekly beer plus cider intake	0.3	0.5	1.9	-1.3	0.2	0.5	0.2	-0.7	-1.4	0.3	-0.6	-0.7	0.6	0.7	0.7	0.2	-0.4	0.3	-0.6	-0.9	0.4	-0.9	0.0	-0.0	1.4	0.2
Basal cell carcinoma (self-reported)	0.3	0.4	1.2	0.9	-0.4	-1.0	-0.6	0.3	-1.0	-0.1	0.1	0.6	-0.8	-0.4	-0.3	-0.7	0.5	-0.8	1.1	0.2	-0.3	0.4	-0.1	-0.4	-1.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	3.3	-0.0	-0.3	-1.2	0.6	-0.8	-0.6	-0.1	0.9	0.6	-0.5	0.0	0.2	-0.0	-1.8	0.3	-0.6	0.2	0.3	-1.0	-0.9	-0.7	0.0	-0.4
Depressed Affect (Nagel 2018)	0.2	0.4	1.6	1.0	-1.2	-1.1	0.0	-0.1	-0.3	0.0	-0.1	0.4	-1.3	-0.9	0.2	-0.3	0.1	-0.3	0.2	0.6	0.0	0.7	0.2	-0.4	-1.2	0.5
Worry (Nagel 2018)	0.2	0.4	3.1	-0.1	0.2	-0.2	0.4	-0.6	0.3	1.1	0.3	1.8	0.0	-0.0	0.5	-0.0	1.5	0.8	1.2	0.1	0.3	0.2	0.4	-0.1	0.4	0.3
Crohns Disease (2017)	0.2	0.5	2.2	1.5	-0.2	-0.5	0.1	0.3	-0.9	-0.2	-0.5	0.6	-0.8	-1.5	0.0	-0.6	0.4	-0.7	-0.5	1.0	-0.6	0.8	1.0	-0.5	-1.2	0.4
Systolic Blood Pressure	0.2	0.9	2.7	-0.0	1.1	0.9	-0.8	0.6	1.6	1.6	-0.8	0.5	0.3	0.9	1.2	1.1	0.9	-0.8	1.0	0.9	1.3	1.4	1.0	0.8	1.0	0.5
Chronotype (morning person)	0.2	0.5	3.8	0.2	-0.3	-0.4	-0.4	-0.3	-0.2	-0.5	-0.3	0.8	-1.1	0.2	0.5	1.1	-1.9	-0.9	-0.1	0.4	0.8	0.1	-1.1	0.4	-0.1	0.0
Hand grip strength (left)	0.2	0.6	2.7	0.2	1.4	0.9	0.8	1.1	-0.5	0.3	0.4	-0.9	0.7	1.0	-0.2	1.2	0.1	0.5	-0.3	-0.0	0.4	0.9	0.6	1.6	0.3	0.9
High blood pressure	0.2	0.7	3.3	-1.8	-0.1	0.9	-0.4	-0.3	-0.1	0.3	-0.6	-0.8	1.3	-0.7	-0.3	0.6	0.3	0.9	-1.1	-0.9	-0.9	-0.8	0.5	-1.0	1.3	-0.9
Nervous feelings	0.2	0.4	1.6	-0.8	-0.2	-0.2	0.1	-0.8	0.7	1.2	-0.5	1.2	0.5	-0.2	-0.6	-0.1	1.3	0.8	0.4	-0.5	-0.5	-0.2	0.2	-0.3	0.3	-0.4
Had menopause	0.2	0.3	1.5	-0.6	0.2	0.9	-0.1	-0.3	-0.3	0.1	0.1	0.7	0.5	0.3	0.4	1.1	0.7	0.4	0.1	-0.1	0.3	-0.5	0.3	-0.1	1.2	-0.6
Migraine (self-reported)	0.2	0.3	1.8	1.0	0.3	-0.2	0.9	0.0	-1.3	0.2	0.7	0.2	-0.2	0.7	0.3	-0.4	-0.3	-1.0	0.7	-0.0	0.4	0.1	-0.4	0.4	-0.5	0.1
Loneliness, isolation	0.2	0.3	1.1	0.5	-0.4	0.6	1.0	-0.1	0.1	1.0	0.5	1.0	-0.1	0.2	0.4	0.3	0.8	0.7	0.2	0.4	0.4	0.6	0.4	0.1	-0.1	0.1
Medication: Paracetamol	0.2	0.3	1.3	0.3	-0.3	0.8	0.1	-0.8	-0.4	-0.1	0.3	-0.7	-0.4	-0.3	1.1	0.0	-1.2	-0.1	-1.0	0.0	0.4	-0.8	-0.5	-0.7	0.8	-0.4
Risk taking	0.2	0.3	1.5	-0.7	-0.1	1.1	0.3	-0.1	-0.5	-0.2	0.6	0.1	-1.2	-0.2	0.0	1.0	-0.3	-1.1	-0.2	-0.1	0.0	-0.7	-1.2	-0.3	0.2	-0.2
Diastolic blood pressure, automated reading	0.2	0.5	2.6	-1.1	-0.3	1.5	-0.9	-0.3	0.1	0.5	-1.6	0.2	1.0	-0.2	0.1	0.5	0.3	-0.6	-0.7	-0.7	-0.4	-0.1	0.8	-0.1	1.1	0.1
Bipolar Disorder or Schizophrenia	0.1	0.3	1.7	-0.1	-0.0	-0.2	-0.8	-0.6	1.3	0.2	-0.1	-0.5	0.0	-0.5	-0.4	-1.2	0.6	-0.7	0.2	-0.1	-0.6	-0.2	-0.3	-0.4	-0.4	-0.3
Schizophrenia (2018)	0.1	0.2	0.9	0.2	0.9	0.4	-0.3	0.3	0.8	0.3	0.2	-0.2	0.4	-0.2	0.5	-0.5	0.8	-0.6	0.6	0.3	0.1	0.6	0.6	0.0	0.1	0.2
HDL Cholesterol	0.1	0.2	1.3	0.2	-0.3	0.4	0.8	0.5	0.7	0.9	0.8	-0.4	0.1	-0.1	-0.3	0.1	0.7	1.1	-0.4	0.0	-0.2	0.1	0.0	0.2	-0.4	0.1
Schizophrenia (2014)	0.1	0.2	1.0	-0.2	0.5	-0.2	-0.7	-0.4	0.6	-0.3	-0.5	-0.3	0.5	-0.6	0.0	-1.0	0.5	-0.9	0.3	-0.4	-0.5	0.1	0.3	-0.5	0.1	-0.1
Heel T-Score	0.1	0.9	4.9	-1.7	0.2	1.0	-0.1	-0.9	0.5	-0.0	0.6	-1.3	0.8	0.7	0.6	1.3	-1.6	1.2	-0.5	-0.7	0.5	-1.2	-0.4	0.8	2.2	-0.1
Waist Hip Ratio (WHR)	0.1	0.5	1.9	0.9	-1.0	-0.7	-1.0	-0.2	-0.4	-0.1	-0.7	0.8	-0.7	-1.4	0.3	-1.0	0.4	-0.7	-0.2	0.7	-0.4	0.2	0.2	-0.5	-0.7	0.5
Lung FVC	0.1	0.7	2.3	-1.1	0.6	0.5	0.0	-0.2	-1.3	-0.9	-1.0	-1.5	0.9	-0.7	0.3	0.3	0.3	-0.3	0.2	-0.8	-0.6	-0.3	0.9	-1.5	1.0	-1.0
Hair Pigment	0.1	2.6	10.6	1.2	1.8	0.6	1.4	2.1	-0.3	1.2	0.3	-0.0	0.6	1.7	1.9	1.5	0.7	-1.7	2.4	0.9	1.8	3.2	3.1	1.6	-0.1	1.9
Tanning	0.1	0.9	3.7	1.5	1.2	0.1	-0.2	1.6	-0.0	0.7	1.1	-0.6	0.4	0.6	-0.3	-1.0	1.9	0.1	1.5	0.2	0.2	1.2	1.4	1.1	-0.8	0.6
Comparative height size at age 10	0.1	0.4	2.4	-0.4	0.3	0.4	0.8	-0.1	0.4	1.4	0.5	1.6	0.6	0.9	-0.0	0.8	0.3	0.7	-0.2	0.3	0.4	0.2	0.4	1.1	0.4	0.7
Heart disease (siblings)	0.1	0.2	0.7	-0.4	-0.0	-0.0	-0.0	0.7	0.3	0.0	0.2	-0.2	0.4	0.5	0.2	0.5	-0.4	0.1	-0.4	0.6	0.6	0.5	0.4	0.8	0.2	0.6

Hub : Genes

CPNE3

Models

Trait associations