Best TWAS P=3.97e-10 · Best GWAS P=2.62e-12 conditioned to 1.38e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | PTK2 | 0.28 | 0.01 | lasso | 4 | 0.09 | 0.00151 | 4.7 | -6.3 | 4.0e-10 | 0.08 | 0.07 | 0.54 | TRUE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | EIF2C2 | 0.07 | 0.06 | lasso | 3 | 0.05 | 0.00002 | 4.9 | 5.3 | 1.5e-07 | -0.06 | 0.01 | 0.99 | TRUE |