[Hub]/) : Traits : Qualifications: College or University degree :

chr8:142,839,492-144,515,639

Best TWAS P=1.75e-11 · Best GWAS P=8.92e-09 conditioned to 0.0308

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum THEM6 0.11 0.03 enet 18 0.06 2.8e-04 4.7 6.7 1.8e-11 0.60 0.15 0.50 TRUE
2 GTEx Artery Coronary LY6K 0.19 0.12 lasso 7 0.16 6.0e-06 4.6 5.2 2.1e-07 0.81 0.06 0.94 FALSE
3 GTEx Brain Cerebellum LY6K 0.36 0.31 lasso 10 0.36 1.8e-11 -4.6 5.1 2.6e-07 0.83 0.22 0.78 FALSE
4 GTEx Brain Hippocampus LY6K 0.20 0.06 enet 16 0.11 1.6e-03 -3.7 5.3 1.3e-07 0.73 0.13 0.46 FALSE
5 GTEx Cells Transformed fibroblasts JRK 0.13 0.04 lasso 5 0.05 1.5e-04 5.8 -5.7 1.5e-08 -0.89 0.01 0.98 FALSE
6 GTEx Esophagus Gastroesophageal Junction LY6K 0.28 0.07 lasso 9 0.12 6.0e-05 4.6 5.7 1.3e-08 0.73 0.03 0.88 FALSE
7 GTEx Esophagus Mucosa LY6K 0.25 0.20 lasso 7 0.22 1.4e-14 5.8 5.7 1.5e-08 0.96 0.00 1.00 FALSE
8 GTEx Esophagus Mucosa CTD-2292P10.2 0.11 0.04 lasso 10 0.04 1.5e-03 5.5 5.7 1.2e-08 0.79 0.02 0.95 FALSE
9 GTEx Nerve Tibial THEM6 0.12 0.07 enet 10 0.06 5.1e-05 -4.6 5.4 5.9e-08 0.86 0.03 0.96 FALSE
10 GTEx Stomach JRK 0.26 0.20 enet 10 0.25 3.7e-12 5.8 5.5 4.9e-08 0.95 0.02 0.98 FALSE
11 GTEx Testis BAI1 0.18 0.13 enet 11 0.15 3.2e-07 4.0 -5.8 8.5e-09 -0.30 0.56 0.40 FALSE
12 GTEx Thyroid CTD-2292P10.2 0.12 0.10 lasso 4 0.08 4.7e-07 5.5 5.7 9.0e-09 0.95 0.02 0.98 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma LY6K 0.05 0.04 lasso 4 0.06 1.7e-12 -4.7 5.2 2.4e-07 0.84 0.00 0.97 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme LY6K 0.12 0.08 enet 5 0.12 1.3e-04 -4.7 5.1 2.9e-07 0.85 0.00 0.40 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LY6K 0.11 0.09 enet 6 0.09 8.2e-06 -4.7 5.2 2.3e-07 0.85 0.00 0.92 FALSE
16 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LY6K 0.07 0.03 enet 8 0.03 4.0e-03 -4.7 5.2 1.8e-07 0.89 0.00 0.16 FALSE
17 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LY6K 0.09 0.04 lasso 5 0.07 7.0e-04 -4.7 5.1 2.6e-07 0.85 0.00 0.70 FALSE