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chr8:142,839,492-144,515,639

Best TWAS P=1.75e-11 · Best GWAS P=8.92e-09 conditioned to 0.0308

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	THEM6	0.11	0.03	enet	18	0.06	2.8e-04	4.7	6.7	1.8e-11	0.60	0.15	0.50	TRUE
11	GTEx	Testis	BAI1	0.18	0.13	enet	11	0.15	3.2e-07	4.0	-5.8	8.5e-09	-0.30	0.56	0.40	FALSE
12	GTEx	Thyroid	CTD-2292P10.2	0.12	0.10	lasso	4	0.08	4.7e-07	5.5	5.7	9.0e-09	0.95	0.02	0.98	FALSE
8	GTEx	Esophagus Mucosa	CTD-2292P10.2	0.11	0.04	lasso	10	0.04	1.5e-03	5.5	5.7	1.2e-08	0.79	0.02	0.95	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	LY6K	0.28	0.07	lasso	9	0.12	6.0e-05	4.6	5.7	1.3e-08	0.73	0.03	0.88	FALSE
5	GTEx	Cells Transformed fibroblasts	JRK	0.13	0.04	lasso	5	0.05	1.5e-04	5.8	-5.7	1.5e-08	-0.89	0.01	0.98	FALSE
7	GTEx	Esophagus Mucosa	LY6K	0.25	0.20	lasso	7	0.22	1.4e-14	5.8	5.7	1.5e-08	0.96	0.00	1.00	FALSE
10	GTEx	Stomach	JRK	0.26	0.20	enet	10	0.25	3.7e-12	5.8	5.5	4.9e-08	0.95	0.02	0.98	FALSE
9	GTEx	Nerve Tibial	THEM6	0.12	0.07	enet	10	0.06	5.1e-05	-4.6	5.4	5.9e-08	0.86	0.03	0.96	FALSE
4	GTEx	Brain Hippocampus	LY6K	0.20	0.06	enet	16	0.11	1.6e-03	-3.7	5.3	1.3e-07	0.73	0.13	0.46	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LY6K	0.07	0.03	enet	8	0.03	4.0e-03	-4.7	5.2	1.8e-07	0.89	0.00	0.16	FALSE
2	GTEx	Artery Coronary	LY6K	0.19	0.12	lasso	7	0.16	6.0e-06	4.6	5.2	2.1e-07	0.81	0.06	0.94	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LY6K	0.11	0.09	enet	6	0.09	8.2e-06	-4.7	5.2	2.3e-07	0.85	0.00	0.92	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	LY6K	0.05	0.04	lasso	4	0.06	1.7e-12	-4.7	5.2	2.4e-07	0.84	0.00	0.97	FALSE
3	GTEx	Brain Cerebellum	LY6K	0.36	0.31	lasso	10	0.36	1.8e-11	-4.6	5.1	2.6e-07	0.83	0.22	0.78	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LY6K	0.09	0.04	lasso	5	0.07	7.0e-04	-4.7	5.1	2.6e-07	0.85	0.00	0.70	FALSE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	LY6K	0.12	0.08	enet	5	0.12	1.3e-04	-4.7	5.1	2.9e-07	0.85	0.00	0.40	FALSE