TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Qualifications: College or University degree
:
←
→
chr14:26,213,713-27,761,335
Best TWAS P=1.7e-08 · Best GWAS P=5.65e-14 conditioned to 2.62e-07
26.2M
26.4M
26.6M
26.8M
27M
27.2M
27.4M
27.6M
27.8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NOVA1
0.05
0.06
enet
6
0.06
5.9e-07
5.6
5.6
1.7e-08
0.61
0.03
0.97
TRUE
1
GTEx
Esophagus Muscularis
NOVA1
0.15
0.04
enet
21
0.02
2.2e-02
5.6
-5.4
7.4e-08
-0.51
0.09
0.75
FALSE
2
The Cancer Genome Atlas
Colon Adenocarcinoma
NOVA1
0.06
0.02
lasso
4
0.03
6.6e-03
5.1
5.2
1.6e-07
0.45
0.03
0.44
FALSE