Best TWAS P=1.7e-08 · Best GWAS P=5.65e-14 conditioned to 2.62e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NOVA1 | 0.15 | 0.04 | enet | 21 | 0.02 | 2.2e-02 | 5.6 | -5.4 | 7.4e-08 | -0.51 | 0.09 | 0.75 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | NOVA1 | 0.06 | 0.02 | lasso | 4 | 0.03 | 6.6e-03 | 5.1 | 5.2 | 1.6e-07 | 0.45 | 0.03 | 0.44 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NOVA1 | 0.05 | 0.06 | enet | 6 | 0.06 | 5.9e-07 | 5.6 | 5.6 | 1.7e-08 | 0.61 | 0.03 | 0.97 | TRUE |