Best TWAS P=2.23e-10 · Best GWAS P=3.48e-09 conditioned to 0.0166
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | GALNT16 | 0.26 | 0.04 | lasso | 7 | 0.04 | 0.033 | -5.6 | -6.3 | 2.2e-10 | -0.64 | 0.04 | 0.70 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DCAF5 | 0.04 | 0.01 | blup | 77 | 0.01 | 0.027 | 5.2 | -5.9 | 3.6e-09 | -0.82 | 0.02 | 0.53 | FALSE |