TWAS hub - DCAF5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0350	0.0244	0.0071	0.006	0.009	0.005	NA	0.004	0.062	0.027	0.082	NA	0.11
2	TCGA	Lung Adenocarcinoma	0.0942	0.0524	0.0087	0.001	0.012	0.007	NA	0.003	0.250	0.013	0.040	NA	0.13

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Frequency of tiredness / lethargy in last 2 weeks	9.7	15.7	27.6	5.2	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	8.6	11.5	23.0	4.8	0.1
Overall health rating	8.3	17.8	34.2	5.8	1.2
Neuroticism score	8.0	16.7	28.8	5.4	-2.1
Sensitivity / hurt feelings	7.8	13.3	16.4	4.0	-3.2
Neuroticism	7.6	18.3	33.9	5.8	-1.7
Fed-up feelings	7.3	13.3	25.0	5.0	-1.2
Depression (Nagel 2018)	6.3	9.4	18.8	4.3	-0.1
Knee pain experienced in last month	5.8	9.0	11.2	3.3	2.6
Qualifications: College or University degree	5.6	17.8	34.8	-5.9	-0.8
Depressed Affect (Nagel 2018)	5.4	11.4	20.7	4.5	-1.5
Eye problems/disorders: Diabetes related eye disease	5.4	5.9	11.6	3.4	-0.5
Neuroticism (Nagel 2018)	5.3	12.4	23.4	4.8	-1.2
Medication: Lansoprazole	5.2	6.0	11.9	3.5	0.1
Osteoporosis (self-reported)	5.1	6.3	9.1	-3.0	1.9
Loneliness, isolation	4.9	6.7	12.9	3.6	-0.7
Frequency of depressed mood in last 2 weeks	4.6	6.4	12.6	3.6	0.4
Pain experienced in last month	4.6	7.6	14.6	-3.8	0.8
Supplements: Fish oil (including cod liver oil)	4.3	5.6	6.2	-2.5	2.2
Verbal and Numeric Reasoning (VNR)	4.2	10.1	10.9	-3.0	-3.3
Supplements: Zinc	4.2	4.6	7.7	-2.8	1.2
Mineral and other dietary supplements	4.2	5.6	6.5	2.6	-2.2
Financial situation satisfaction	4.2	5.3	9.7	3.1	-0.9
Qualifications: None of the above	4.1	8.9	9.4	3.1	2.9
Medication: Paracetamol	4.1	6.8	13.6	3.7	0.3
Alcohol usually taken with meals	3.8	6.2	11.6	-3.4	0.9
Heart attack	3.8	4.9	8.3	2.9	-1.2
Intelligence (Savage-Jansen 2018)	3.6	11.2	12.0	-3.2	-3.5
Lupus	3.6	5.5	9.3	3.0	1.3
Chest pain or discomfort	3.6	5.2	5.6	2.4	-2.2
Qualifications: nursing, teaching	3.5	5.4	10.8	-3.3	-0.2
Heart attack/myocardial infarction (self-reported)	3.5	4.6	7.9	2.8	-1.1
Current tobacco smoking	3.4	5.5	10.0	3.2	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	3.4	4.0	7.0	-2.6	-1.0
Mood swings	3.4	6.1	10.5	3.2	-1.3
Nervous feelings	3.3	6.2	12.3	3.5	-0.3
Alcohol intake frequency.	3.3	7.8	15.6	3.9	0.1
Back pain experienced in last month	3.3	4.9	5.3	2.3	-2.1
Average weekly champagne plus white wine intake	3.3	4.6	8.2	-2.9	0.9
Medication: Paracetamol	3.3	5.1	9.4	3.1	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	3.2	4.9	8.8	3.0	-1.0
Headache pain in last month	3.2	5.5	10.9	3.3	-0.1
Pulse wave peak to peak time	3.2	3.8	4.8	-1.7	2.2
Neck or shoulder pain in last month	3.2	4.5	8.2	2.9	-1.0
Tinnitus: Yes, but not now, but have in the past	3.1	3.3	6.2	2.5	-0.6
Leg fat percentage (left)	3.1	11.3	20.1	4.5	-1.6
Worry (Nagel 2018)	3.0	6.4	11.8	3.4	-0.9
Ever highly irritable/argumentative for 2 days	3.0	3.6	4.6	2.1	-1.6
Pulse wave Arterial Stiffness index	2.9	3.4	5.0	1.3	-2.2
Age at first live birth	2.9	5.1	9.9	-3.1	-0.6
Long-standing illness, disability or infirmity	2.9	4.4	8.9	3.0	-0.0
Ever had hysterectomy (womb removed)	2.8	3.1	5.4	2.3	0.9
Leg fat percentage (right)	2.8	10.3	17.9	4.2	-1.6
Smoking status: Current	2.8	4.4	8.2	2.9	-0.8
Financial difficulties in last 2 years	2.7	3.6	7.2	2.7	-0.0
Medication: Cholesterol lowering	2.7	4.2	7.6	2.8	-0.9
Worry too long after embarrassment	2.7	4.6	4.9	2.1	-2.2
Emphysema/chronic bronchitis	2.7	3.0	5.3	2.3	-0.8
Age at First Birth	2.6	3.8	7.1	-2.7	-0.7
Fluid intelligence score	2.6	5.3	6.5	-2.5	-2.0
Pulse rate	2.6	4.4	5.9	2.4	-1.7
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.2	6.3	2.5	-0.3
Coronary Artery Disease (CAD)	2.5	3.0	5.7	0.4	2.4
Worrier / anxious feelings	2.5	4.7	9.3	3.1	-0.3
Medication for pain relief, constipation, heartburn	2.5	4.3	8.6	-2.9	0.2
Unable to work because of sickness or disability	2.5	3.2	4.8	1.3	2.2
Medication: Omeprazole (e.g. Zanprol)	2.5	3.1	5.0	1.1	-2.2
Number of treatments/medications taken	2.4	4.3	7.9	2.8	-0.8
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	3.7	-1.9	1.3
Qualifications: A levels/AS levels or equivalent	2.3	5.0	10.0	-3.2	0.1
Serious illness, injury or assault of a close relative in last 2 years	2.3	2.7	4.2	-1.1	-2.0
Miserableness	2.3	4.1	8.1	2.8	-0.3
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.3	5.9	2.4	-0.9
Hair/balding pattern: Pattern 4	2.2	5.3	10.4	-0.5	-3.2
Medication: Gliclazide	2.2	2.5	4.5	0.7	-2.1
Heart disease (siblings)	2.2	2.7	5.3	0.4	-2.3
Lung FEV1/FVC ratio	2.1	10.6	18.6	-1.6	-4.3
Townsend deprivation index at recruitment	2.1	3.0	3.1	1.7	1.8
Number of incorrect matches in round	2.1	3.5	7.0	2.6	0.0
Mouth/teeth dental problems	2.1	3.2	4.5	-1.3	2.1
Guilty feelings	2.1	3.1	5.8	2.4	0.7
Medication: Bendroflumethiazide	2.1	3.2	5.8	2.4	0.8
Ulcerative Colitis (UC)	2.0	3.7	5.8	-1.3	2.4
Ulcerative Colitis	2.0	2.9	4.4	-2.1	1.2
Hearing difficulty/problems with background noise	2.0	3.3	5.9	-0.8	-2.4
Alcohol intake versus 10 years previously	2.0	3.1	4.6	2.1	1.2
Birth weight	2.0	4.3	8.5	0.2	2.9
Osteoarthritis (self-reported)	2.0	2.6	2.9	1.5	1.7
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	3.4	-1.9	-1.6
Leg pain on walking	1.9	2.3	3.7	1.9	1.0
Diabetes diagnosed by doctor	1.9	3.1	3.3	1.7	-1.8
Commuting to job workplace: Public transport	1.9	2.2	3.9	-2.0	0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.1	4.7	1.9	2.2
Fractured/broken bones in last 5 years	1.8	2.3	4.1	-0.7	2.0
Leg fat mass (left)	1.8	7.1	13.6	3.7	-0.7
Medication: Metformin	1.7	2.4	3.6	1.1	-1.9
Relative age voice broke	1.7	2.7	5.3	-2.3	0.1
Forced vital capacity (FVC)	1.7	6.7	9.5	-1.9	3.1
Medication: Omeprazole	1.7	2.1	3.1	1.0	-1.8
Leg fat mass (right)	1.7	6.8	13.0	3.6	-0.8
Average weekly beer plus cider intake	1.7	2.4	4.8	2.2	-0.2
Neuroticism (2016)	1.6	2.3	4.7	2.2	-0.1
BMI	1.6	9.2	12.9	3.6	-2.3
Smoking Status	1.6	3.9	7.4	2.7	-0.6
Mouth/teeth dental problems: Dentures	1.6	2.8	4.7	2.2	-0.9
Lung cancer (father)	1.6	1.9	2.5	1.6	1.1
Forced vital capacity (FVC), Best measure	1.6	5.7	7.7	-1.9	2.8
Body fat percentage	1.6	6.3	11.4	3.4	-1.0
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	3.4	-1.8	0.7
Major Depression (MDD)	1.5	1.8	3.3	0.5	1.8
Chronotype (morning person)	1.5	3.4	6.8	0.1	2.6
Diabetes (mother)	1.5	1.9	3.2	0.8	-1.8
Maternal smoking around birth	1.5	2.2	3.7	1.9	-0.8
Qualifications: CSEs or equivalent	1.5	1.9	2.6	1.6	1.1
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.5	1.9	0.6
Supplements: Calcium	1.5	1.6	2.2	-1.0	1.5
Hand grip strength (left)	1.4	3.8	6.0	2.5	-1.2
Diabetes (self-reported)	1.4	2.2	2.9	1.2	-1.7
Time employed in main current job	1.4	1.6	3.1	-1.8	-0.2
Noisy workplace	1.4	1.7	1.7	1.3	1.3
Length of working week for main job	1.4	1.5	2.8	-0.5	-1.7
Shortness of breath walking on level ground	1.4	1.6	3.2	1.8	0.0
Crohns Disease (2012)	1.3	2.0	2.7	-1.6	-1.2
Stomach or abdominal pain in last month	1.3	1.7	1.8	1.4	-1.2
Falls in the last year	1.3	1.8	3.6	0.2	1.9
Prospective memory result	1.3	1.5	2.3	1.5	0.9
Eye problems/disorders: Cataract	1.3	1.5	2.3	-1.5	0.8
Irritability	1.3	2.1	4.3	2.1	-0.1
Irritable Bowel Disease (IBD)	1.2	3.0	5.0	-2.2	1.0
Hypothyroidism (self reported)	1.2	2.7	5.1	2.2	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	3.6	1.3	1.9
Body mass index (BMI)	1.2	5.2	9.2	3.0	-1.1
Arm fat percentage (right)	1.2	4.6	7.4	2.7	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	2.2	1.5	-1.0
Medication: Ibuprofen	1.2	1.4	1.7	1.3	1.1
Whole body fat mass	1.2	5.2	9.8	3.1	-0.8
Suffer from ‘nerves’	1.2	1.9	3.8	1.9	-0.4
Illnesses of father: Heart disease	1.2	1.7	2.3	-1.0	-1.5
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	1.8	1.1	1.3
Trunk fat percentage	1.1	4.6	8.7	2.9	-0.7
Chronic bronchitis/emphysema (father)	1.1	1.2	1.6	1.3	-1.0
Medication: Amlodipine	1.1	1.5	2.9	-1.7	-0.3
Health satisfaction	1.1	1.4	2.0	1.4	-0.9
Age started oral contraceptive pill	1.1	1.4	1.5	-1.2	1.1
Alcohol drinker status: Previous	1.1	1.2	2.3	1.5	0.4
Body Mass Index (BMI) (2010)	1.0	1.4	1.5	1.2	-1.1
Blood Red Count	1.0	10.0	18.9	4.3	-1.1
Type 2 Diabetes (T2D) (2018)	1.0	1.9	3.0	0.9	-1.7
Lung FVC	1.0	5.0	7.9	-1.5	2.8
Medication: Co-codamol	1.0	1.1	1.3	1.0	1.1
Trunk fat mass	1.0	4.3	8.4	2.9	-0.5
Number of live births	1.0	1.5	1.6	1.3	1.1
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	4.8	-2.2	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	5.3	-2.3	0.9
Arm fat mass (right)	1.0	4.0	7.5	2.7	-0.7
Heart disease (mother)	1.0	1.2	1.4	-1.2	1.0
Number of full sisters	1.0	1.3	2.4	1.6	0.3
Age at last live birth	1.0	1.5	2.9	-1.7	0.2
Average weekly red wine intake	1.0	1.5	2.2	-1.5	0.8
Commuting to job workplace: Walk	1.0	1.1	2.0	-1.4	0.5
Medication: Blood pressure	1.0	1.9	3.4	1.9	0.6
Bipolar Disorder (2018)	0.9	1.5	2.3	-0.8	1.5
Bipolar Disorder or Schizophrenia	0.9	2.2	4.3	-0.4	2.1
Medication for hormone replacement therapy	0.9	1.0	1.9	1.4	0.1
Severe depression (siblings)	0.9	1.0	1.9	0.3	-1.4
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	1.3	1.1	-0.9
High blood pressure (mother)	0.9	1.2	2.2	-0.4	-1.5
Hair/balding pattern: Pattern 3	0.9	1.4	2.5	-1.6	0.6
Asthma	0.9	1.7	3.1	-0.5	1.8
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	1.6	-1.3	1.1
Number of children fathered	0.9	1.0	1.1	1.0	-1.0
Handedness (chirality/laterality): Left-handed	0.9	1.0	1.9	-0.4	-1.4
Risk taking	0.9	1.4	1.5	-1.1	1.2
Ever depressed for a whole week	0.9	1.2	2.3	1.5	0.0
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	2.3	0.3	1.5
Triglycerides	0.8	1.2	2.2	1.5	0.5
Hearing difficulty/problems: Yes	0.8	1.2	2.4	-0.3	-1.5
Taking other prescription medications	0.8	1.3	2.5	1.6	-0.2
Serious illness, injury or assault to yourself	0.8	0.9	1.1	1.1	0.9
Medication: Atenolol	0.8	1.0	1.7	1.3	0.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.0	0.5	-1.4
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.9	1.7	-0.3
Eye problems/disorders: None of the above	0.8	1.0	1.8	-0.4	-1.3
Mouth/teeth dental problems: Loose teeth	0.8	1.0	1.5	0.7	-1.2
Medication: Seretide 50 evohaler	0.8	0.9	1.3	1.1	0.7
Commuting to job workplace: Car/motor vehicle	0.8	0.9	0.9	0.9	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.6	0.5	-1.3
Number of self-reported non-cancer illnesses	0.8	1.4	2.0	1.4	-0.9
Commuting to job workplace: Cycle	0.8	1.0	1.2	-1.1	0.9
Alzheimer’s Disease (in mother)	0.7	0.9	1.0	-1.0	0.9
Crohns Disease (2017)	0.7	1.5	2.4	-1.5	-0.8
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.1	-0.7	-1.1
Relative age of first facial hair	0.7	1.4	2.8	-0.2	1.7
Supplements: Glucosamine	0.7	0.9	1.6	-1.3	0.4
Waist circumference	0.7	2.6	5.2	2.3	0.1
Pain all over the body in last month	0.7	0.8	1.2	1.1	-0.6
Medication: Ramipril	0.7	0.9	1.7	0.0	-1.3
Weight	0.7	3.3	6.5	2.6	0.1
Hip circumference	0.7	2.9	4.7	2.2	-1.1
Impedance of arm (left)	0.7	3.4	4.0	-2.0	1.7
Blood clot in the leg (DVT)	0.7	0.9	1.4	0.6	1.2
Wheeze or whistling in the chest in last year	0.7	1.3	2.6	1.6	0.0
Comparative height size at age 10	0.7	4.1	7.8	-0.6	2.8
Arm fat percentage (left)	0.7	2.7	4.7	2.2	-0.8
Arm fat mass (left)	0.7	2.9	5.7	2.4	-0.4
Alzheimer’s Disease (including proxy)	0.6	0.9	1.2	-0.8	1.1
Blood Eosinophil Count	0.6	4.8	8.9	-3.0	0.8
Allergy or Eczema	0.6	1.5	3.0	-1.7	0.1
Diabetes (father)	0.6	0.7	1.4	0.3	-1.2
Hayfever, allergic rhinitis or eczema	0.6	1.2	1.3	-1.1	-1.1
Happiness	0.6	0.8	1.3	1.1	-0.5
Pulse wave reflection index	0.6	0.7	1.2	-0.5	-1.1
Mean time to correctly identify matches	0.6	1.1	1.7	-0.7	1.3
Friendships satisfaction	0.6	0.7	1.1	1.1	-0.6
Vascular/heart problems diagnosed by doctor	0.6	1.6	3.2	-1.8	0.0
Schizophrenia (2018)	0.5	1.0	2.0	0.1	1.4
Reaction Time	0.5	0.9	1.0	-0.9	1.0
Mean Putamen Volume	0.5	0.6	1.0	-1.0	-0.5
Blood Platelet Count	0.5	6.3	12.2	3.5	-0.6
Angina	0.5	0.6	1.2	0.3	1.1
Pack years adult smoking proportion	0.5	0.7	0.9	0.9	-0.7
Average weekly fortified wine intake	0.5	0.6	1.1	-0.3	1.1
Multivitamins +/- minerals	0.5	0.6	0.7	-0.9	-0.7
Past tobacco smoking	0.5	0.9	1.2	-1.1	-0.8
Had other major operations	0.5	0.6	0.9	-0.6	-0.9
Father’s age at death	0.5	0.7	0.9	-1.0	-0.6
Exposure to tobacco smoke at home	0.5	0.6	1.1	1.1	0.0
Tense / ‘highly strung’	0.5	0.8	1.5	1.2	-0.3
Birth weight of first child	0.5	0.8	1.2	1.1	-0.7
Glaucoma (self-reported)	0.5	0.6	1.3	-0.1	1.1
Gout (self-reported)	0.5	0.7	1.4	-1.2	0.1
Illnesses of siblings: Diabetes	0.5	0.6	0.9	0.9	-0.5
Breast cancer (self-reported)	0.5	0.6	1.0	1.0	-0.5
Asthma (self-reported)	0.5	1.1	2.0	-0.3	1.4
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.0	1.0	-0.3
Eye problems/disorders: Glaucoma	0.5	0.6	0.7	0.9	0.7
Medication: Atorvastatin	0.5	0.6	0.7	0.8	-0.8
Schizophrenia vs Biploar Disorder	0.4	0.6	0.8	0.6	0.9
Primary Biliary Cirrhosis	0.4	0.5	1.1	-0.1	-1.0
Rheumatoid Arthritis	0.4	0.5	0.8	0.4	-0.9
Schizophrenia (2014)	0.4	0.9	1.3	0.8	1.1
Heel T-Score	0.4	2.8	5.7	0.0	2.4
Hand grip strength (right)	0.4	1.1	1.9	1.4	-0.5
Medication: Levothyroxine sodium	0.4	0.7	1.3	1.2	-0.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.9	-0.9	-0.4
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.7	-0.8	0.6
Medication: Aspirin	0.4	0.6	1.2	1.1	-0.0
Medication for cholesterol	0.4	0.6	0.9	-0.9	0.5
Ever taken oral contraceptive pill	0.4	0.4	0.8	0.2	0.9
High cholesterol (Self-reported)	0.4	0.6	1.0	1.0	-0.5
Diastolic blood pressure, automated reading	0.4	1.2	2.3	1.5	-0.2
Prostate Cancer	0.3	0.4	0.8	-0.3	0.9
Bipolar Disorder (2011)	0.3	0.3	0.5	-0.3	0.7
Blood White Count	0.3	2.2	2.4	1.5	1.4
Waist Hip Ratio (WHR)	0.3	1.4	2.7	-0.3	1.6
Vitamin and mineral supplements	0.3	0.4	0.6	0.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.6	-0.8	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.5	0.6	0.7
Standing height	0.3	3.4	5.6	-1.1	2.4
Comparative body size at age 10	0.3	0.9	1.8	-1.3	-0.1
Pulse rate, automated reading	0.3	1.1	1.4	0.9	-1.2
Had major operations	0.3	0.4	0.7	-0.8	0.2
Family relationship satisfaction	0.3	0.4	0.5	0.5	0.7
Smoking status: Previous	0.3	0.5	0.7	0.8	0.5
Ever had bowel cancer screening	0.3	0.3	0.7	0.0	0.8
Illnesses of father: None of the above (group 1)	0.3	0.4	0.6	-0.5	0.8
Arm fat-free mass (left)	0.3	1.8	3.5	1.9	-0.3
Myopia	0.3	0.5	0.9	-0.1	-0.9
Arm predicted mass (left)	0.3	1.8	3.4	1.9	-0.3
Breast Cancer	0.2	0.4	0.7	-0.9	0.1
Ovarian Cancer	0.2	0.3	0.6	-0.7	-0.0
HDL Cholesterol	0.2	0.3	0.4	-0.5	-0.7
LDL Cholesterol	0.2	0.4	0.4	0.6	0.6
Height	0.2	3.2	4.9	-1.2	2.2
Respiratory disease	0.2	0.4	0.8	-0.9	-0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.5	-0.2	0.7
Impedance of leg (left)	0.2	1.0	2.1	1.4	-0.1
Hair/balding pattern: Pattern 2	0.2	0.2	0.4	0.6	-0.1
Had menopause	0.2	0.2	0.4	-0.6	-0.0
Medication: Simvastatin	0.2	0.2	0.3	0.4	-0.5
Illnesses of siblings	0.2	0.3	0.6	-0.2	0.7
Impedance of arm (right)	0.2	1.0	1.2	-1.1	0.9
Loud music exposure frequency	0.2	0.2	0.4	-0.2	-0.6
Exposure to tobacco smoke outside home	0.2	0.3	0.5	0.7	-0.3
Number of full brothers	0.2	0.2	0.4	0.6	-0.2
Angina (self-reported)	0.2	0.2	0.4	0.2	0.6
Medication: Allopurinol	0.2	0.2	0.3	-0.5	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.7	0.1	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.5	0.7	-0.2
Medication: Aspirin	0.2	0.2	0.4	0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.4	-0.6	-0.6
Mother’s age at death	0.2	0.3	0.5	-0.7	0.3
Illnesses of father: High blood pressure	0.2	0.3	0.3	-0.5	0.6
Alcohol drinker status: Never	0.2	0.3	0.3	0.6	0.4
Ever smoked	0.2	0.3	0.5	0.7	0.4
Cholesterol lowering medication	0.2	0.3	0.4	-0.7	-0.4
Pack years of smoking	0.2	0.4	0.5	0.7	-0.5
Fasting Glucose	0.1	0.2	0.3	-0.3	-0.5
HbA1C	0.1	0.1	0.2	-0.5	0.0
Cardiovascular Disease	0.1	0.2	0.5	0.7	0.0
Hair Pigment	0.1	3.0	5.9	2.4	0.5
Tanning	0.1	1.1	2.2	1.5	0.2
Average weekly spirits intake	0.1	0.1	0.2	0.5	0.1
Impedance of leg (right)	0.1	0.6	1.1	1.1	-0.1
Age when periods started (menarche)	0.1	0.3	0.4	0.7	-0.3
High blood pressure	0.1	0.2	0.4	0.6	-0.2
Sitting height	0.1	0.5	0.9	-1.0	0.3
Allergy	0.1	0.3	0.6	0.8	-0.1
Depression (self-reported)	0.1	0.1	0.2	0.2	-0.5
Illnesses of mother	0.1	0.1	0.1	0.4	0.1
Breastfed as a baby	0.1	0.1	0.2	0.4	-0.2
Peak expiratory flow (PEF)	0.1	0.3	0.4	-0.7	-0.4
High blood pressure (siblings)	0.1	0.2	0.2	0.4	0.4
Arm fat-free mass (right)	0.1	0.5	0.7	0.8	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.1	0.4	-0.1
Arm predicted mass (right)	0.1	0.6	1.3	1.1	0.2
Supplements: Vitamin C	0.1	0.1	0.1	-0.4	-0.0
Whole body fat-free mass	0.1	0.4	0.6	0.8	0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.1	-0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	0.5	0.3
Whole body water mass	0.1	0.4	0.6	0.8	0.3
Hearing aid user	0.1	0.1	0.2	-0.4	0.1
Medication: Lisinopril	0.1	0.2	0.3	0.5	-0.3
Basal metabolic rate	0.1	0.8	1.4	1.2	0.3
Number of operations (self-reported)	0.1	0.2	0.3	0.1	-0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	-0.4	-0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	0.3	-0.3
Impedance of whole body	0.1	0.3	0.3	-0.5	0.6
Alzheimer’s Disease (in father)	0.0	0.0	0.0	0.1	-0.0
Systolic Blood Pressure	0.0	0.1	0.1	0.3	-0.3
Systolic blood pressure, automated reading	0.0	0.0	0.1	0.0	-0.3
Leg fat-free mass (left)	0.0	0.2	0.2	0.4	0.5
Leg predicted mass (left)	0.0	0.2	0.3	0.5	0.5
Trunk fat-free mass	0.0	0.3	0.5	0.7	0.2
Trunk predicted mass	0.0	0.2	0.4	0.7	0.1
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	-0.2	-0.1
Medication: Blood pressure	0.0	0.0	0.1	0.3	-0.0
Migraine (self-reported)	0.0	0.0	0.0	0.2	0.0
Hypertension (Self-reported)	0.0	0.1	0.1	0.3	-0.0
Leg fat-free mass (right)	0.0	0.2	0.4	0.3	0.6
Leg predicted mass (right)	0.0	0.2	0.3	0.2	0.6
Wears glasses or contact lenses	0.0	0.0	0.0	-0.2	-0.2

Hub : Genes

DCAF5

Models

Trait associations