Best TWAS P=1.65e-07 · Best GWAS P=3.51e-08 conditioned to 0.0802
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | RFT1 | 0.14 | 0.12 | enet | 16 | 0.10 | 4.4e-05 | -5.5 | -5.1 | 3.0e-07 | 0.97 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Muscle Skeletal | NEK4 | 0.07 | 0.03 | lasso | 5 | 0.03 | 9.6e-04 | -4.6 | -5.2 | 1.7e-07 | 0.93 | 0.04 | 0.93 | TRUE |
| 3 | METSIM | Adipose | SFMBT1 | 0.04 | 0.04 | lasso | 1 | 0.03 | 3.5e-05 | -5.2 | 5.2 | 2.4e-07 | -0.98 | 0.01 | 0.99 | FALSE |