[Hub]/) : Traits : Qualifications: None of the above :

chr11:94,805,896-96,276,010

Best TWAS P=1.87e-13 · Best GWAS P=2.9e-13 conditioned to 0.22

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM76B 0.06 0.02 lasso 3 0.01 8.1e-03 -6.0 6.4 1.9e-10 -0.90 0.05 0.94 FALSE
2 GTEx Adipose Subcutaneous CEP57 0.17 0.12 enet 26 0.14 3.1e-11 -7.0 -7.2 8.0e-13 0.91 0.02 0.98 FALSE
3 GTEx Adipose Subcutaneous AP001877.1 0.16 0.04 enet 35 0.05 1.0e-04 -6.0 -6.2 5.9e-10 0.59 0.06 0.93 FALSE
4 GTEx Adipose Visceral Omentum CEP57 0.10 0.16 lasso 1 0.13 3.3e-07 -6.9 -6.9 6.5e-12 0.99 0.02 0.98 FALSE
5 GTEx Artery Tibial MTMR2 0.17 0.09 enet 23 0.11 1.2e-08 -7.1 5.7 9.2e-09 -0.75 0.02 0.98 FALSE
6 GTEx Brain Caudate basal ganglia AP001877.1 0.21 0.03 lasso 15 0.01 1.4e-01 -7.0 -6.4 1.2e-10 0.89 0.03 0.84 FALSE
7 GTEx Brain Cerebellar Hemisphere AP001877.1 0.29 0.24 lasso 7 0.25 5.0e-07 -7.1 -6.9 6.8e-12 0.96 0.04 0.96 FALSE
8 GTEx Brain Putamen basal ganglia AP001877.1 0.39 0.05 lasso 15 0.08 6.5e-03 -7.0 -5.6 1.9e-08 0.78 0.04 0.79 FALSE
9 GTEx Breast Mammary Tissue CEP57 0.11 0.06 lasso 3 0.06 4.5e-04 -7.1 -7.0 2.0e-12 0.93 0.02 0.96 FALSE
10 GTEx Breast Mammary Tissue (Male) CEP57 0.08 0.06 lasso 2 0.03 5.8e-02 -6.2 -6.2 4.3e-10 0.82 0.05 0.47 FALSE
11 GTEx Breast Mammary Tissue (Female) CEP57 0.01 0.01 lasso 2 -0.01 7.0e-01 -5.9 -6.6 3.9e-11 0.87 0.04 0.46 FALSE
12 GTEx Colon Transverse CEP57 0.12 0.11 lasso 3 0.11 6.8e-06 -6.0 -6.8 1.4e-11 0.96 0.02 0.98 FALSE
13 GTEx Esophagus Mucosa CEP57 0.14 0.14 lasso 3 0.10 6.0e-07 -6.1 -6.5 7.7e-11 0.89 0.06 0.94 FALSE
14 GTEx Esophagus Mucosa AP001877.1 0.09 0.00 lasso 3 0.00 5.4e-01 -7.3 -7.4 1.9e-13 0.93 0.02 0.82 TRUE
15 GTEx Esophagus Muscularis CEP57 0.15 0.05 enet 21 0.06 9.0e-05 -6.1 -6.7 3.0e-11 0.85 0.05 0.95 FALSE
16 GTEx Esophagus Muscularis AP001877.1 0.17 0.09 lasso 6 0.10 6.2e-07 -6.0 -6.2 4.7e-10 0.87 0.14 0.85 FALSE
17 GTEx Liver FAM76B 0.43 0.08 enet 32 0.13 1.4e-04 -7.0 -5.5 4.2e-08 0.73 0.04 0.92 FALSE
18 GTEx Liver CEP57 0.24 0.10 enet 23 0.01 2.1e-01 -7.0 -7.2 4.8e-13 0.92 0.03 0.86 FALSE
19 GTEx Lung CEP57 0.12 0.05 enet 16 0.04 4.4e-04 -7.1 -6.7 1.7e-11 0.92 0.04 0.96 FALSE
20 GTEx Muscle Skeletal CEP57 0.15 0.18 lasso 9 0.18 1.8e-17 -7.0 -6.8 1.4e-11 0.93 0.04 0.96 FALSE
21 GTEx Nerve Tibial MTMR2 0.14 0.10 enet 16 0.08 2.0e-06 -7.1 7.2 4.8e-13 -0.95 0.03 0.97 FALSE
22 GTEx Nerve Tibial CEP57 0.15 0.08 lasso 6 0.07 1.9e-05 -6.0 -6.5 7.2e-11 0.92 0.04 0.96 FALSE
23 GTEx Nerve Tibial AP001877.1 0.15 0.05 lasso 3 0.05 1.6e-04 -7.0 -7.3 3.5e-13 0.92 0.04 0.96 FALSE
24 GTEx Pancreas CEP57 0.19 0.10 lasso 13 0.08 3.6e-04 -6.1 -6.5 6.1e-11 0.91 0.05 0.95 FALSE
25 GTEx Skin Not Sun Exposed Suprapubic CEP57 0.14 0.06 enet 10 0.05 9.6e-04 -5.4 -6.6 5.1e-11 0.84 0.04 0.96 FALSE
26 GTEx Skin Sun Exposed Lower leg CEP57 0.19 0.14 enet 24 0.16 4.1e-13 -6.1 -6.8 8.1e-12 0.92 0.05 0.95 FALSE
27 GTEx Small Intestine Terminal Ileum AP001877.1 0.34 0.14 lasso 22 0.11 1.8e-03 -6.2 -6.8 1.1e-11 0.88 0.04 0.87 FALSE
28 GTEx Testis MTMR2 0.22 0.18 lasso 3 0.18 2.8e-08 -7.1 7.2 5.7e-13 -0.97 0.02 0.98 FALSE
29 GTEx Thyroid CEP57 0.11 0.01 enet 15 0.03 1.8e-03 -6.1 -6.1 1.2e-09 0.73 0.07 0.87 FALSE
30 METSIM Adipose CEP57 0.06 0.07 lasso 1 0.06 1.8e-09 -6.2 -6.2 4.7e-10 0.85 0.04 0.96 FALSE
31 ROSMAP Brain Pre-frontal Cortex AP001877.1 0.17 0.27 lasso 12 0.27 3.6e-35 -7.0 -7.0 2.5e-12 0.95 0.04 0.96 FALSE
32 YFS Blood CEP57 0.04 0.03 lasso 5 0.03 3.4e-11 -6.9 -6.0 2.2e-09 0.85 0.04 0.96 FALSE
33 YFS Blood FAM76B 0.14 0.25 lasso 10 0.26 8.1e-83 -6.9 7.0 2.7e-12 -0.94 0.04 0.96 FALSE
34 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CEP57 0.02 0.00 blup 53 0.01 6.0e-02 -6.0 -6.5 6.4e-11 0.90 0.02 0.59 FALSE