Best TWAS P=1.37e-09 · Best GWAS P=2.88e-07 conditioned to 0.876
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | CCDC18 | 0.29 | 0.07 | lasso | 10 | 0.15 | 9.2e-05 | 5.1 | -5.5 | 3.3e-08 | -0.92 | 0.03 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TMED5 | 0.08 | 0.06 | enet | 12 | 0.07 | 3.5e-08 | 5.1 | -6.1 | 1.4e-09 | -0.86 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DR1 | 0.16 | 0.18 | blup | 29 | 0.19 | 4.1e-18 | 5.0 | 5.1 | 3.0e-07 | 0.94 | 0.00 | 0.99 | FALSE |