TWAS hub - TMED5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0640	0.0210	7.3e-09	0.073	0.072	0.088	0.075	0.083	2.9e-09	4.1e-09	6.7e-11	1.9e-09	2.4e-10
2	GTEx	Brain Cerebellar Hemisphere	0.3660	0.1150	7.8e-06	0.058	NA	0.107	NA	0.068	1.3e-02	NA	1.1e-03	NA	7.9e-03
3	GTEx	Cells Transformed fibroblasts	0.1030	0.0370	1.1e-06	0.113	NA	0.059	NA	0.087	8.4e-09	NA	3.0e-05	NA	4.6e-07
4	GTEx	Testis	0.2730	0.0710	6.3e-12	0.309	NA	0.285	NA	0.302	3.1e-14	NA	4.1e-13	NA	6.9e-14
5	METSIM	Adipose	0.0523	0.0194	2.9e-07	0.068	0.045	0.059	0.051	0.060	1.8e-10	2.5e-07	3.4e-09	3.2e-08	2.4e-09
6	NTR	Blood	0.0137	0.0065	5.4e-04	0.008	0.009	0.002	0.008	0.005	1.1e-03	5.2e-04	6.3e-02	7.2e-04	5.9e-03
7	ROSMAP	Brain Pre-frontal Cortex	0.1124	0.0352	2.2e-14	0.105	0.127	0.129	0.129	0.124	2.2e-13	4.6e-16	2.7e-16	2.7e-16	1.1e-15
8	YFS	Blood	0.1436	0.0330	0.0e+00	0.186	0.214	0.217	0.216	0.218	1.1e-58	2.4e-68	3.2e-69	5.5e-69	1.1e-69
9	TCGA	Breast Invasive Carcinoma	0.0571	0.0392	2.0e-03	0.001	0.001	0.005	NA	0.002	2.1e-01	1.9e-01	2.6e-02	NA	1.0e-01
10	TCGA	Glioblastoma Multiforme	0.0840	0.0520	5.8e-03	0.046	0.028	0.001	NA	0.017	1.6e-02	4.7e-02	2.9e-01	NA	9.6e-02
11	TCGA	Brain Lower Grade Glioma	0.0824	0.0444	1.6e-07	0.062	0.068	0.068	NA	0.065	1.4e-07	3.9e-08	3.5e-08	NA	7.4e-08
12	TCGA	Ovarian Serous Cystadenocarcinoma	0.0480	0.0280	1.3e-03	0.053	0.034	0.040	NA	0.037	1.9e-04	2.1e-03	9.7e-04	NA	1.5e-03
13	TCGA	Prostate Adenocarcinoma	0.0727	0.0562	4.6e-04	0.021	0.024	0.049	NA	0.027	2.6e-03	1.3e-03	7.1e-06	NA	7.4e-04
14	TCGA	Stomach Adenocarcinoma	0.0500	0.0320	4.8e-04	0.057	0.043	0.050	NA	0.051	6.0e-05	4.2e-04	1.6e-04	NA	1.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Qualifications: College or University degree	16.6	52.2	72.4	8.4	6.8	7.9	8.5	5.3	7.0	7.4	7.0	6.6	8.3	8.5	7.1	3.4	7.2
Medication: Paracetamol	10.6	17.6	22.9	-4.7	-3.9	-4.8	-4.8	-4.0	-4.0	-4.2	-4.5	-3.8	-4.6	-4.4	-4.3	-2.1	-3.8
Blood Eosinophil Count	10.3	79.7	110.2	10.3	9.4	9.4	9.7	9.1	9.6	10.0	10.5	2.6	10.3	7.4	7.7	5.0	10.1
HDL Cholesterol	10.2	16.9	27.4	-4.7	-4.2	-4.3	-4.8	-2.4	-4.5	-4.3	-3.7	0.0	-4.9	-5.2	-3.8	-3.7	-4.3
Mouth/teeth dental problems: Dentures	9.7	16.3	23.6	-4.2	-3.5	-4.4	-4.7	-2.5	-3.2	-4.3	-3.6	-4.9	-4.5	-4.7	-4.5	-2.6	-4.0
Average weekly red wine intake	9.5	14.0	22.2	4.4	4.7	4.3	4.2	2.6	4.3	3.9	3.7	1.0	4.5	3.7	2.6	1.4	4.4
Qualifications: None of the above	7.7	16.6	36.7	-4.5	-4.0	-4.7	-4.8	-1.8	-4.4	-3.4	-3.2	-4.2	-4.7	-6.1	-3.5	-1.8	-3.9
Medication: Paracetamol	7.7	11.9	16.3	-3.8	-3.2	-4.0	-4.0	-2.8	-2.9	-3.3	-3.5	-3.3	-3.9	-4.0	-3.7	-2.0	-3.2
Qualifications: A levels/AS levels or equivalent	7.6	16.7	23.9	4.7	4.0	4.4	4.9	2.7	3.2	3.8	3.9	4.2	4.8	4.7	4.5	1.9	4.3
Irritable Bowel Disease (IBD)	6.7	16.0	22.4	4.5	4.0	4.5	4.4	4.1	3.2	4.0	4.7	2.3	4.6	3.9	3.9	3.0	4.2
Rheumatoid Arthritis	6.7	9.3	14.0	-3.2	-2.0	-3.5	-3.5	-2.7	-3.1	-3.7	-3.2	-1.0	-3.7	-2.9	-3.2	-2.2	-3.4
Qualifications: NVQ or HND or HNC or equivalent	6.4	7.7	11.5	-2.9	-2.5	-3.4	-3.3	-1.9	-2.2	-2.7	-2.7	-2.8	-3.1	-2.6	-3.2	-1.6	-3.1
Medication for pain relief, constipation, heartburn	6.2	10.6	15.4	3.6	2.8	3.9	3.7	3.5	2.9	3.4	3.7	3.1	3.5	3.5	3.1	1.1	2.7
Allergy or Eczema	5.8	15.4	22.5	4.2	2.9	4.1	4.4	2.4	4.6	4.7	3.5	4.1	4.4	4.7	3.6	2.2	3.9
Hayfever, allergic rhinitis or eczema	5.8	12.6	18.5	3.9	2.4	3.8	4.0	2.2	4.0	4.3	3.2	3.2	4.1	4.2	3.1	2.3	3.8
Crohns Disease (2017)	5.6	12.3	17.6	3.9	3.4	4.2	3.9	4.0	2.5	3.3	4.2	1.9	4.0	2.9	3.8	2.6	3.5
Sensitivity / hurt feelings	5.5	9.4	14.4	-2.7	-3.8	-3.5	-3.0	-3.8	-3.0	-3.3	-3.7	-2.6	-3.0	-1.8	-3.4	-1.6	-3.0
Mouth/teeth dental problems	5.5	8.4	16.4	2.8	3.0	3.2	3.1	2.7	1.1	3.0	3.1	3.0	3.1	1.9	4.0	2.6	3.0
Noisy workplace	5.1	6.3	8.9	-3.0	-2.5	-2.8	-2.9	-2.5	-2.5	-2.7	-2.8	-1.8	-2.9	-2.2	-2.4	-0.4	-2.5
Alcohol usually taken with meals	4.9	8.0	13.6	3.0	3.7	3.5	3.3	1.1	2.2	2.7	2.3	2.1	3.4	3.7	2.3	1.5	3.2
Family relationship satisfaction	4.8	5.9	10.4	2.6	1.6	2.5	3.0	0.6	3.0	2.5	1.9	1.9	3.0	3.0	2.4	0.9	3.2
Mood swings	4.8	8.6	18.2	-2.9	-2.6	-3.1	-2.8	-4.3	-3.6	-2.9	-3.9	-1.6	-2.9	-2.2	-2.7	-2.1	-2.3
LDL Cholesterol	4.6	7.3	14.7	-2.6	-2.4	-2.9	-2.9	-2.3	-3.8	-2.4	-3.0	0.0	-3.0	-2.0	-2.5	-2.9	-3.2
Crohns Disease (2012)	4.4	7.2	10.2	3.2	2.9	3.1	3.0	2.3	1.9	2.2	2.9	1.1	3.2	2.9	2.3	2.4	3.1
Knee pain experienced in last month	4.3	6.7	11.6	-2.3	-2.7	-2.8	-3.0	-2.1	-2.0	-2.3	-2.7	-2.4	-2.9	-2.5	-3.4	-2.3	-2.7
Ever had prostate specific antigen (PSA) test	4.2	4.9	9.2	-2.5	-2.1	-2.3	-2.2	-2.9	-1.3	-2.0	-2.8	-1.6	-2.2	-0.8	-3.0	-1.8	-2.1
Blood Red Count	4.1	40.1	51.4	-7.0	-5.2	-7.0	-7.1	-5.4	-6.1	-7.2	-6.4	-6.1	-7.0	-6.6	-6.7	-4.2	-5.9
Age at first live birth	4.1	7.3	10.3	2.9	2.7	3.1	3.2	2.1	1.4	2.8	2.6	3.2	3.0	2.9	2.9	1.9	2.6
Osteoporosis (self-reported)	4.1	5.0	7.4	2.6	1.8	2.5	2.4	2.7	2.4	2.3	2.6	1.6	2.3	2.1	2.3	1.9	1.7
Depressed Affect (Nagel 2018)	3.9	8.3	11.8	-3.0	-3.4	-3.4	-3.1	-2.9	-2.8	-2.5	-3.1	-2.6	-3.0	-3.0	-2.8	-2.1	-2.3
Lupus	3.8	5.8	14.9	-2.0	-1.9	-2.6	-2.5	-1.6	-1.7	-1.9	-2.2	-3.9	-2.3	-2.1	-3.5	-2.2	-2.1
Commuting to job workplace: Walk	3.8	4.1	6.9	2.6	2.1	2.5	2.4	2.3	1.7	1.8	2.4	0.9	2.3	1.5	2.1	1.3	1.9
Medication: Co-codamol	3.7	4.2	6.5	-1.9	-1.7	-2.5	-2.5	-1.4	-2.4	-2.2	-2.0	-1.8	-2.3	-2.2	-2.1	-0.9	-2.2
Neuroticism score	3.7	7.8	13.6	-2.7	-3.7	-3.2	-2.7	-3.4	-2.7	-2.5	-3.4	-2.0	-2.8	-2.1	-2.8	-2.0	-2.4
Comparative height size at age 10	3.6	19.7	39.8	-4.1	-6.3	-4.6	-5.3	-1.4	-4.3	-2.6	-3.4	-4.1	-5.0	-6.0	-4.2	-3.5	-4.9
Mean time to correctly identify matches	3.5	6.6	10.0	-3.2	-2.4	-3.0	-2.7	-2.9	-2.9	-2.9	-3.0	-0.5	-2.9	-2.1	-1.9	-1.4	-2.5
Neuroticism	3.4	8.1	13.7	-2.9	-3.7	-3.4	-2.9	-3.0	-2.6	-2.2	-3.1	-2.7	-2.9	-2.8	-2.6	-2.5	-2.2
Commuting to job workplace: Cycle	3.4	4.1	6.7	2.6	2.1	2.6	2.5	1.7	1.4	2.0	2.1	1.6	2.4	2.5	1.3	0.9	2.0
Heart disease (mother)	3.3	4.1	8.9	1.8	1.6	2.0	1.8	3.0	2.1	2.3	2.5	1.2	2.0	0.8	2.5	2.1	1.4
Allergy	3.2	7.4	12.0	-3.0	-1.5	-2.7	-3.1	-1.5	-2.8	-3.5	-2.4	-2.5	-3.3	-3.3	-2.4	-2.1	-3.1
Illnesses of mother	3.2	3.9	5.9	-2.4	-1.8	-2.0	-2.2	-1.6	-2.4	-1.8	-2.0	-1.7	-2.2	-1.9	-2.1	-0.6	-2.2
Medication: Aspirin	3.2	4.2	8.5	2.0	2.9	2.2	2.2	1.6	1.9	1.7	2.1	0.4	2.3	1.6	2.1	2.1	2.6
Ulcerative Colitis (UC)	3.1	5.8	8.2	2.7	2.3	2.5	2.6	2.3	2.2	2.5	2.8	1.2	2.7	2.9	2.0	1.6	2.7
Major Depression (MDD)	2.9	3.5	11.4	-2.3	-2.0	-1.9	-2.3	-0.1	-1.2	-1.1	-1.2	-1.8	-2.2	-3.4	-1.3	-1.0	-2.0
High blood pressure	2.9	8.1	15.4	2.4	2.6	2.5	2.4	3.3	3.9	3.6	3.5	-2.2	3.0	0.9	1.8	2.6	3.4
Blood Platelet Count	2.8	32.0	60.4	6.4	7.0	5.9	6.6	3.3	7.8	5.1	5.7	0.5	6.9	5.4	4.0	0.2	7.7
Fluid intelligence score	2.7	5.7	13.6	2.7	2.7	2.5	2.8	1.0	2.1	2.7	1.9	2.4	2.8	3.7	1.6	0.4	2.4
Hypertension (Self-reported)	2.7	7.5	13.5	2.2	2.7	2.4	2.3	3.3	3.7	3.5	3.4	-2.1	2.9	0.6	1.9	2.3	3.3
Gout (self-reported)	2.6	3.5	7.1	2.0	1.7	1.8	2.0	1.9	2.7	2.3	2.2	0.3	2.1	1.2	1.6	0.7	2.2
Relative age voice broke	2.5	3.8	6.1	2.5	1.5	2.3	2.2	1.5	1.9	1.6	2.0	1.5	2.2	2.1	1.9	1.6	1.9
Hayfever/allergic rhinitis (self-reported)	2.5	3.3	6.7	2.1	1.0	1.7	2.0	1.5	2.3	2.6	2.0	0.8	2.1	1.5	1.4	0.8	2.2
Pain experienced in last month	2.5	4.2	7.1	1.6	2.4	2.5	2.4	1.5	1.7	1.8	2.0	2.1	2.2	1.9	2.7	1.0	2.2
Ulcerative Colitis	2.3	3.4	5.3	2.3	1.4	1.9	2.0	1.7	1.4	1.8	2.2	1.6	2.0	2.1	1.5	1.2	2.1
Neuroticism (Nagel 2018)	2.2	5.1	7.5	-2.4	-2.7	-2.5	-2.1	-2.7	-2.4	-1.8	-2.6	-2.4	-2.1	-2.1	-2.0	-1.8	-1.4
Mean Putamen Volume	2.2	2.6	4.6	1.7	2.0	1.9	2.0	0.2	2.1	1.0	1.1	1.0	1.9	1.8	1.6	0.0	2.1
Happiness	2.2	2.6	7.1	1.6	1.3	1.4	1.9	0.6	2.4	2.0	1.4	-0.2	2.0	0.8	1.7	-0.2	2.7
Depression (self-reported)	2.2	2.7	6.9	-1.5	-1.5	-1.8	-1.9	-0.3	-2.2	-1.1	-0.9	-2.6	-1.7	-2.6	-1.0	0.0	-1.4
Medication: Amlodipine	2.2	3.1	7.5	1.1	1.9	1.9	1.4	2.7	1.4	2.2	2.3	0.9	1.5	0.5	2.2	2.0	1.4
Alcohol intake frequency.	2.2	5.1	8.2	-2.2	-2.9	-2.6	-2.2	-2.5	-2.8	-2.0	-2.7	-1.4	-2.4	-2.1	-1.8	-1.4	-2.1
Hypothyroidism (self reported)	2.1	4.9	11.4	-2.1	-1.4	-2.5	-2.3	-2.5	-2.6	-3.4	-2.6	-1.6	-2.3	-1.8	-1.4	-1.3	-2.1
Headache pain in last month	2.1	3.5	7.0	-1.6	-1.8	-1.8	-1.7	-2.6	-2.2	-2.1	-2.4	-2.1	-1.6	-1.3	-2.2	-0.8	-1.2
Medication: Lisinopril	2.1	2.7	4.5	1.4	2.1	1.5	1.6	1.9	2.1	2.0	2.1	0.2	1.7	0.9	1.4	0.7	1.9
Vascular/heart problems diagnosed by doctor	2.1	5.8	10.3	-1.8	-2.5	-2.0	-1.9	-2.9	-3.2	-2.8	-3.0	2.4	-2.5	-0.2	-1.7	-2.3	-3.0
High blood pressure (mother)	2.0	2.9	5.3	2.3	1.5	1.8	1.8	2.0	1.7	1.7	1.9	0.7	1.9	1.8	1.0	1.4	1.5
Comparative body size at age 10	2.0	5.6	9.4	2.1	3.1	2.5	2.3	2.6	2.9	2.4	2.8	0.9	2.6	0.8	2.7	1.5	2.5
Suffer from ‘nerves’	2.0	3.2	6.6	-2.0	-2.6	-2.2	-2.0	-1.3	-1.9	-1.1	-1.8	-1.0	-2.1	-2.1	-1.4	-0.9	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.4	4.5	-1.6	-1.7	-1.7	-1.8	-1.3	-0.3	-0.6	-1.6	-1.4	-1.8	-1.4	-2.1	-1.6	-1.7
Medication: Aspirin	2.0	2.7	5.9	1.4	2.4	1.7	1.8	0.9	1.7	1.4	1.5	-0.1	1.9	1.3	1.7	1.5	2.2
Medication: Blood pressure	2.0	3.7	6.4	1.7	2.5	1.9	1.6	2.5	2.2	2.2	2.4	-1.7	1.9	0.5	1.3	1.8	1.9
Relative age of first facial hair	1.9	3.9	6.3	2.1	1.9	2.3	2.2	1.6	2.5	2.4	2.0	0.6	2.3	1.5	2.0	1.1	2.3
Medication for hormone replacement therapy	1.9	2.1	4.2	-1.1	-1.4	-1.5	-1.4	-1.7	-0.5	-1.5	-1.6	-2.1	-1.3	-1.3	-1.9	-1.7	-0.9
Exposure to tobacco smoke outside home	1.9	2.6	4.8	-1.6	-2.2	-1.6	-1.8	-0.2	-1.4	-1.4	-1.1	-1.6	-1.8	-2.2	-1.4	-0.7	-2.1
Health satisfaction	1.9	2.4	5.6	1.6	1.2	1.6	1.8	0.8	2.1	2.0	1.5	-0.3	1.9	0.9	1.4	0.8	2.4
Shortness of breath walking on level ground	1.9	2.3	5.2	1.3	0.9	1.1	1.3	1.8	2.3	2.2	1.9	0.6	1.4	0.1	1.6	1.0	2.0
Hearing aid user	1.9	2.2	6.0	1.3	1.3	1.8	1.9	-0.3	1.0	0.8	0.9	0.3	2.0	2.5	1.3	0.7	2.3
Commuting to job workplace: Public transport	1.9	2.3	3.9	2.0	1.0	1.5	1.8	1.4	1.4	1.9	1.8	0.2	1.8	1.9	0.9	0.1	1.8
Alcohol drinker status: Never	1.9	2.3	3.7	1.4	1.9	1.6	1.8	1.1	0.9	1.5	1.5	1.5	1.6	1.5	1.8	0.8	1.7
Pack years of smoking	1.9	2.8	4.6	-1.8	-1.3	-2.1	-1.9	-1.2	-1.3	-1.9	-1.5	-2.1	-1.8	-1.5	-2.0	-0.6	-1.5
Friendships satisfaction	1.8	2.2	5.9	1.8	0.6	1.6	1.7	0.6	2.4	1.8	1.2	0.4	1.8	2.0	0.3	0.1	1.8
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	6.2	-1.2	-2.3	-1.7	-1.6	-1.9	0.0	-1.3	-2.1	-0.5	-1.7	-0.3	-2.5	-2.2	-2.1
Medication: Levothyroxine sodium	1.7	2.8	5.8	-1.5	-0.8	-1.9	-1.8	-1.7	-2.0	-2.4	-1.9	-1.5	-1.8	-1.1	-1.7	-1.1	-1.7
Number of incorrect matches in round	1.7	2.8	11.7	-1.5	-2.5	-1.8	-2.0	0.1	-1.0	-1.2	-0.7	-1.9	-1.7	-3.4	-0.4	0.4	-1.3
Worrier / anxious feelings	1.7	3.1	7.8	-1.3	-1.9	-1.6	-1.4	-2.8	-1.0	-1.1	-2.5	-1.0	-1.6	-0.4	-2.4	-2.5	-1.5
Illness, injury, bereavement, stress in last 2 years	1.7	2.0	4.3	1.5	0.9	1.3	1.1	1.6	0.6	1.6	1.5	2.0	1.1	2.0	1.0	2.1	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	9.8	1.4	3.1	2.4	2.2	1.4	1.6	1.4	1.9	0.2	2.3	1.2	2.0	0.8	2.5
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	4.1	-2.0	-1.9	-2.0	-1.8	-0.6	-1.2	-1.2	-1.3	-0.4	-1.8	-1.8	-1.0	0.2	-1.6
Prospective memory result	1.6	2.0	5.0	-1.7	-2.2	-1.5	-1.5	-0.9	-1.5	-1.6	-1.4	-0.5	-1.5	-1.9	-0.6	0.4	-1.3
Neck or shoulder pain in last month	1.6	2.3	7.0	-0.8	-1.2	-1.6	-1.6	-1.1	-1.1	-1.4	-1.4	-2.0	-1.6	-0.9	-2.7	-1.3	-1.5
Fasting Glucose	1.5	1.8	7.0	-0.9	-1.6	-1.4	-1.2	-1.5	-0.2	-0.5	-1.4	-1.7	-1.2	-0.3	-2.6	-1.0	-1.0
Height	1.5	28.2	56.1	-4.7	-7.5	-5.0	-5.9	-2.5	-7.0	-2.9	-4.5	-3.3	-6.0	-5.9	-5.5	-5.5	-5.7
Supplements: Zinc	1.5	1.6	4.1	1.0	1.1	1.2	1.6	-0.5	1.6	1.2	0.6	1.2	1.5	1.6	1.3	0.3	2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.1	1.5	1.3	1.0	1.4	0.7	1.8	1.3	1.2	-1.1	1.6	1.1	0.7	0.4	1.7
Had menopause	1.4	1.7	4.0	-1.4	-1.0	-1.3	-1.1	-2.0	-1.1	-1.7	-1.5	-0.9	-1.2	-0.9	-1.2	-1.8	-0.4
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	6.8	-1.5	-0.9	-1.8	-1.7	-2.2	-1.8	-2.6	-2.1	-1.3	-1.7	-0.8	-1.4	-0.9	-1.5
Chest pain or discomfort	1.4	2.1	4.1	2.0	1.7	1.5	1.6	1.7	0.7	1.6	1.7	-0.1	1.7	1.2	0.5	0.8	1.6
Basal cell carcinoma (self-reported)	1.4	1.7	3.0	1.6	1.7	1.6	1.3	1.1	1.6	1.5	1.4	-0.2	1.4	1.0	0.8	-0.7	1.4
Neuroticism (2016)	1.3	1.9	4.1	-1.4	-1.9	-1.6	-1.4	-1.2	-1.1	-0.9	-1.4	-2.0	-1.2	-1.5	-1.3	-1.0	-1.0
Triglycerides	1.3	2.1	3.3	1.4	1.8	1.5	1.6	0.5	1.6	1.8	1.3	0.0	1.8	1.7	1.2	1.1	1.8
Trunk fat percentage	1.3	5.0	20.8	-1.7	-2.0	-2.3	-2.4	-0.8	-2.1	-2.0	-1.4	-4.6	-1.9	-3.3	-2.0	0.3	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	8.9	-1.7	-1.9	-2.2	-1.4	-3.0	-1.1	-1.8	-2.4	-1.4	-1.3	-0.6	-1.6	-0.7	-1.0
Number of live births	1.3	1.8	4.0	-1.2	-0.9	-1.8	-1.4	-1.4	-1.3	-2.0	-1.6	-0.8	-1.5	-0.8	-1.3	-0.2	-1.7
Breastfed as a baby	1.3	1.6	3.8	1.3	1.5	1.7	1.7	-0.0	1.7	0.8	0.7	0.9	1.6	2.0	0.8	0.1	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	5.9	-1.2	-2.4	-1.3	-1.4	-1.7	-0.4	-0.8	-1.9	-0.6	-1.5	-0.8	-1.9	-0.9	-1.7
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	7.1	1.5	2.0	1.6	1.7	0.1	1.5	1.1	0.9	0.8	1.7	2.7	0.3	-0.1	1.5
Medication: Seretide 50 evohaler	1.3	1.5	3.0	1.3	1.0	1.3	1.4	1.1	1.7	1.6	1.4	0.7	1.4	1.1	0.9	0.2	1.3
Supplements: Fish oil (including cod liver oil)	1.3	1.7	2.9	-1.4	-1.7	-1.2	-1.6	-0.6	-0.5	-0.9	-1.2	-0.9	-1.6	-1.7	-1.3	-1.4	-1.7
Alzheimer’s Disease (in mother)	1.2	1.3	7.5	-0.7	-0.3	-1.0	-1.1	-1.1	-0.7	-0.9	-1.0	-2.7	-0.9	-1.4	-1.4	-0.4	-0.4
Breast Cancer	1.2	2.9	5.2	1.7	2.3	2.0	2.1	0.4	1.2	1.0	1.2	2.0	1.9	2.2	1.8	1.2	1.9
Respiratory disease	1.2	2.6	5.7	1.6	0.7	1.8	1.8	1.7	1.5	2.4	1.9	1.2	1.8	0.9	1.7	0.7	1.9
Fed-up feelings	1.2	2.2	6.4	-1.1	-1.6	-1.7	-1.6	-1.0	-1.5	-1.0	-1.3	-2.5	-1.4	-1.9	-1.5	-0.4	-0.9
Qualifications: CSEs or equivalent	1.2	1.6	3.8	-1.6	-1.0	-1.1	-1.4	-1.3	-0.7	-1.6	-1.3	-1.9	-1.2	-1.3	-1.1	-0.1	-0.8
Pain all over the body in last month	1.2	1.3	4.6	-1.4	-1.6	-1.5	-1.2	-1.0	-0.9	-1.1	-1.1	-0.6	-1.1	-2.1	0.1	-0.1	-0.7
Commuting to job workplace: Car/motor vehicle	1.2	1.3	3.8	-1.5	-1.3	-1.2	-1.2	-1.9	-0.3	-0.8	-1.7	-0.7	-1.1	-0.9	-1.0	-0.8	-0.9
Long-standing illness, disability or infirmity	1.2	1.8	3.8	0.8	0.5	0.9	0.9	1.8	1.4	1.9	1.8	-1.8	1.2	-0.4	1.0	1.3	1.6
Osteoarthritis (self-reported)	1.2	1.6	6.2	-0.8	-1.4	-1.4	-1.4	-0.4	-0.4	-0.5	-0.9	-2.5	-1.2	-1.4	-1.8	-0.2	-1.1
Number of self-reported non-cancer illnesses	1.2	2.0	3.9	1.0	0.2	1.2	1.1	1.5	1.7	2.0	1.6	-2.0	1.4	0.4	0.5	1.9	1.7
Wears glasses or contact lenses	1.2	1.4	3.1	-0.8	-0.6	-1.1	-1.1	-1.6	-0.2	-1.3	-1.3	-1.8	-1.0	-0.8	-1.8	-1.3	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	3.7	-0.9	-1.5	-1.6	-1.6	0.1	0.3	0.2	-0.5	-1.9	-1.2	-1.9	-1.3	-0.3	-1.0
Alcohol drinker status: Previous	1.2	1.3	3.4	-1.0	-1.4	-1.1	-1.3	-0.4	-1.9	-0.8	-1.0	0.3	-1.5	-1.4	-0.6	0.1	-1.7
Prostate Cancer	1.1	1.5	2.8	1.4	1.5	1.6	1.5	0.8	0.7	0.5	1.3	0.1	1.6	1.4	1.0	1.3	1.7
Average weekly fortified wine intake	1.1	1.3	2.4	-1.1	-0.7	-0.8	-0.9	-1.6	-1.6	-1.4	-1.4	-1.4	-0.9	-0.6	-1.5	-1.2	-0.4
Taking other prescription medications	1.1	1.7	5.5	-1.4	-1.6	-1.3	-1.4	-0.4	-1.6	-0.6	-0.7	-2.4	-1.1	-2.1	-0.9	0.5	-0.6
Stomach or abdominal pain in last month	1.1	1.4	2.3	-1.4	-1.4	-1.4	-1.3	-0.8	-1.1	-0.9	-1.1	-1.3	-1.3	-1.5	-1.0	-0.5	-1.0
Trunk fat mass	1.1	4.7	21.3	-1.5	-2.3	-2.1	-2.2	-0.2	-2.0	-1.5	-1.0	-4.6	-1.7	-3.5	-1.7	0.1	-1.3
Falls in the last year	1.1	1.5	4.7	-1.2	-0.3	-1.0	-0.7	-2.2	-1.2	-1.4	-1.7	-1.3	-0.8	0.5	-1.9	-1.0	-0.6
Pulse rate	1.1	1.8	5.5	1.1	2.3	1.2	1.5	0.6	0.7	1.1	1.3	0.6	1.5	0.3	1.9	-0.1	2.1
Asthma	1.1	2.1	4.3	1.6	0.5	1.4	1.7	1.2	1.1	2.1	1.5	1.3	1.8	1.2	1.8	0.7	1.8
High blood pressure (siblings)	1.1	1.6	5.5	1.1	0.7	0.9	0.7	2.4	1.3	0.7	1.9	-1.0	0.9	-0.8	1.0	1.8	1.2
Medication: Blood pressure	1.1	1.9	4.3	0.2	0.9	0.9	0.9	1.8	2.1	1.8	1.8	-0.6	1.2	-1.0	1.7	1.2	1.9
Irritability	1.1	1.9	4.7	-1.7	-2.2	-1.7	-1.4	-1.0	-0.9	-0.4	-1.2	-1.3	-1.2	-1.7	-1.4	-1.3	-1.0
Reaction Time	1.0	2.0	3.9	-1.5	-1.7	-1.8	-1.4	-1.5	-2.0	-1.5	-1.6	0.3	-1.5	-1.2	-0.6	-0.6	-1.4
Cardiovascular Disease	1.0	3.4	7.0	1.2	1.9	1.6	1.4	2.1	2.0	2.3	2.2	-2.6	2.0	-0.2	1.2	1.2	2.3
Ever used hormone-replacement therapy (HRT)	1.0	1.3	2.8	-1.2	-0.6	-1.3	-1.2	-0.7	-1.4	-1.0	-1.0	-1.4	-1.1	-1.7	-0.9	-1.3	-0.7
Maternal smoking around birth	1.0	1.4	4.4	-1.0	-0.4	-1.0	-1.1	-1.5	0.1	-1.4	-1.2	-2.1	-1.0	-1.2	-1.2	-1.5	-0.5
Blood clot in the leg (DVT)	1.0	1.3	2.9	-1.5	-1.5	-1.7	-1.4	-0.5	-1.0	-0.8	-0.9	-0.2	-1.3	-1.4	-0.6	0.2	-1.2
Migraine (self-reported)	1.0	1.2	6.2	-0.9	-0.8	-1.1	-0.6	-2.5	-0.9	-1.4	-1.7	-0.1	-0.7	0.3	-1.0	-0.6	-0.3
Medication: Allopurinol	1.0	1.3	3.7	1.3	0.5	0.7	1.1	1.5	1.9	1.4	1.5	-0.3	1.3	0.6	0.8	0.2	1.2
Whole body fat mass	1.0	4.2	21.2	-1.4	-2.0	-1.9	-2.0	-0.1	-1.6	-1.4	-0.9	-4.6	-1.6	-3.3	-1.6	-0.1	-1.2
Illnesses of father: Heart disease	1.0	1.4	3.2	1.3	0.8	1.5	1.2	1.8	1.3	1.4	1.6	0.4	1.2	0.3	1.3	-0.1	1.0
Loneliness, isolation	1.0	1.4	2.9	-1.1	-1.7	-1.2	-0.9	-1.4	-1.1	-1.2	-1.3	-1.2	-1.1	-1.4	-0.6	-1.4	-0.6
Mother’s age at death	1.0	1.3	2.1	1.1	1.4	1.4	1.3	0.7	0.7	1.1	1.1	0.9	1.3	1.4	0.9	1.0	1.1
Pain type(s) experienced in last month: Hip pain	1.0	1.2	3.6	-1.1	-0.9	-1.0	-0.9	-1.9	-0.6	-1.1	-1.6	-0.6	-0.9	-0.3	-1.3	-1.4	-0.7
Intelligence (Savage-Jansen 2018)	0.9	2.6	8.5	1.6	1.3	1.6	1.9	-0.5	0.9	1.3	0.6	2.3	1.8	2.9	1.4	0.7	1.8
Age at First Birth	0.9	1.2	2.3	1.4	0.7	1.3	1.3	0.8	1.3	1.4	1.0	1.3	1.1	1.5	0.5	0.1	0.9
HbA1C	0.9	1.0	2.9	0.9	1.4	1.0	0.9	1.0	1.1	0.3	0.9	1.3	0.7	1.2	0.6	1.7	0.4
Standing height	0.9	9.1	27.7	-2.5	-5.3	-2.6	-3.2	-0.6	-3.7	-0.6	-2.0	-1.9	-3.2	-3.6	-2.8	-3.5	-3.2
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.7	0.5	0.2	0.6	0.5	1.6	1.3	0.8	1.3	1.6	0.4	-0.5	1.9	0.3	0.4
Body fat percentage	0.9	3.6	20.2	-1.3	-1.4	-1.8	-1.8	-0.4	-1.6	-1.7	-0.9	-4.5	-1.4	-2.9	-1.5	0.7	-0.9
Worry too long after embarrassment	0.9	1.5	3.4	-1.1	-1.1	-1.5	-1.0	-1.8	-1.2	-1.3	-1.6	-0.5	-1.1	-0.9	-0.6	-1.6	-1.0
Asthma (self-reported)	0.9	1.8	4.0	1.5	0.3	1.3	1.6	1.2	1.1	2.0	1.4	1.1	1.7	1.1	1.5	0.7	1.6
Worry (Nagel 2018)	0.8	1.7	2.8	-1.5	-1.7	-1.4	-1.2	-1.6	-1.3	-0.7	-1.6	-1.1	-1.3	-1.3	-0.8	-1.2	-0.8
Number of treatments/medications taken	0.8	1.5	9.1	-1.1	-1.3	-1.1	-1.2	-0.1	-0.6	-0.1	-0.4	-3.0	-0.8	-1.6	-1.4	0.4	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.0	1.4	0.5	0.7	1.1	1.1	1.4	1.7	1.2	-0.2	1.2	0.5	1.1	0.5	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	7.5	-1.3	-1.3	-1.8	-0.9	-2.7	-1.0	-1.5	-2.0	-0.7	-0.9	-0.3	-1.1	-0.6	-0.5
Sitting height	0.8	5.8	16.9	-1.9	-4.1	-2.2	-2.5	-1.1	-2.8	-0.9	-2.0	-1.6	-2.5	-2.7	-2.4	-3.0	-2.3
Leg fat mass (right)	0.8	3.0	21.3	-1.2	-1.2	-1.4	-1.5	-0.1	-0.9	-1.2	-0.6	-4.6	-1.0	-2.9	-1.2	0.4	-0.6
Leg pain on walking	0.8	1.0	2.8	-1.3	-1.0	-1.1	-1.0	-1.4	-0.5	-0.4	-1.2	0.0	-1.1	-1.7	-0.0	-0.2	-0.6
Ever taken oral contraceptive pill	0.8	0.9	2.4	1.0	0.6	1.1	1.1	0.6	1.1	0.6	0.9	0.9	1.1	1.6	0.7	1.1	0.8
Leg fat mass (left)	0.8	3.1	22.1	-1.2	-1.2	-1.5	-1.6	-0.1	-0.9	-1.1	-0.6	-4.7	-1.0	-2.9	-1.3	0.3	-0.6
Alzheimer’s Disease (in father)	0.7	0.8	2.0	1.1	1.2	0.9	1.0	0.4	0.6	0.6	0.8	-0.1	1.2	0.8	0.8	0.4	1.4
Systolic Blood Pressure	0.7	3.6	8.6	1.6	2.0	1.7	1.2	2.5	1.3	1.7	2.4	-2.9	1.7	-0.5	1.2	2.2	2.3
Ever had hysterectomy (womb removed)	0.7	0.8	1.3	-1.2	-0.8	-0.9	-0.9	-1.0	0.1	-0.6	-1.1	-0.2	-1.0	-0.4	-1.0	-1.2	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.7	1.4	0.3	0.6	0.9	1.2	1.9	1.5	1.2	-0.3	1.0	0.2	0.6	0.4	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.8	-0.7	-0.6	-1.3	-0.8	-1.7	-1.2	-1.1	-1.4	-0.6	-0.7	-0.3	-0.9	-0.3	-0.4
Impedance of arm (left)	0.7	3.1	9.0	-1.4	-1.7	-1.9	-1.9	-1.8	-3.0	-1.8	-1.9	-0.0	-2.1	-1.2	-1.6	-0.5	-1.7
Ever highly irritable/argumentative for 2 days	0.7	0.9	4.5	-0.4	-0.2	-0.4	0.1	-1.8	1.1	-0.2	-0.9	-1.2	0.1	-0.3	-0.3	-2.1	0.9
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.5	-1.2	-1.9	-1.1	-1.1	-0.3	-0.4	-0.5	-0.8	0.1	-1.1	-0.9	-0.8	-0.6	-1.3
Birth weight	0.7	1.5	3.1	-1.4	-1.3	-1.2	-1.6	-0.5	-1.1	-0.5	-1.0	-0.6	-1.6	-1.8	-1.2	-1.4	-1.3
Medication: Omeprazole	0.7	0.9	3.5	-0.5	-1.0	-1.1	-1.1	0.2	0.8	0.5	-0.2	-1.9	-0.7	-1.4	-1.0	-0.2	-0.5
Pulse rate, automated reading	0.7	2.2	4.8	1.1	2.1	1.3	1.1	1.5	0.5	1.0	1.9	-1.1	1.5	-0.2	1.8	1.9	2.2
Age at last live birth	0.7	1.0	2.9	1.2	1.0	1.1	1.2	0.5	-0.1	0.9	0.7	1.0	1.2	1.7	0.6	1.2	0.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.2	-0.7	-1.4	-1.1	-0.8	-0.2	0.1	0.2	-0.6	0.3	-1.0	-0.4	-1.3	-1.5	-1.1
Qualifications: nursing, teaching	0.7	1.1	4.2	1.1	0.6	1.2	1.3	-0.4	0.5	0.3	0.2	2.0	1.0	2.0	0.7	0.4	0.7
Ever smoked	0.7	1.2	4.1	-1.1	-0.8	-0.9	-1.0	-1.1	-0.7	-0.8	-1.1	-2.0	-0.9	-0.9	-1.6	-0.8	-0.6
Unable to work because of sickness or disability	0.7	0.9	3.3	-1.3	-0.6	-0.9	-0.8	-0.5	-0.5	-0.2	-0.6	-1.8	-0.7	-1.7	-0.4	-1.1	-0.4
Impedance of whole body	0.7	3.5	8.6	-1.6	-1.4	-1.9	-2.0	-2.2	-2.9	-2.1	-2.2	-0.1	-2.1	-0.9	-2.0	-0.9	-1.8
Blood White Count	0.6	4.3	14.0	1.8	1.9	0.9	1.9	0.4	3.6	0.9	1.8	-3.4	2.4	1.1	0.1	0.2	3.7
Smoking Status	0.6	1.4	3.7	0.4	1.0	1.0	1.0	1.0	1.6	1.2	1.2	-1.9	1.3	0.1	0.5	0.9	1.7
Hearing difficulty/problems: Yes	0.6	1.0	6.3	0.4	0.9	0.9	1.1	-0.9	0.6	0.2	-0.2	1.4	0.9	2.5	0.3	-0.2	0.4
Systolic blood pressure, automated reading	0.6	1.8	15.4	0.5	0.5	0.1	-0.2	1.4	-0.3	0.0	1.1	-3.9	0.2	-1.1	-0.5	1.8	0.7
Medication: Metformin	0.6	0.8	2.6	-1.1	-1.4	-0.9	-1.1	0.3	-0.7	-0.4	-0.4	-0.3	-1.1	-1.6	-0.0	0.9	-0.9
Severe depression (siblings)	0.6	0.7	1.3	1.1	0.3	1.1	0.9	0.2	1.1	0.6	0.4	-0.7	1.1	0.9	0.7	1.0	0.9
Pack years adult smoking proportion	0.6	0.9	2.7	-1.0	-0.4	-1.2	-1.0	-0.6	-0.6	-1.2	-0.8	-1.6	-0.9	-0.8	-1.2	-0.1	-0.7
Impedance of leg (right)	0.6	2.8	5.1	-1.5	-0.9	-1.6	-1.8	-2.2	-2.2	-2.2	-2.1	-0.2	-1.9	-0.6	-1.9	-1.2	-1.7
Medication: Lansoprazole	0.6	0.7	1.6	-1.0	-0.5	-0.7	-0.9	-1.1	0.2	-0.6	-0.9	-0.4	-0.9	-0.5	-1.3	-1.2	-0.5
Pulse wave Arterial Stiffness index	0.6	0.7	2.4	-0.9	-0.3	-0.8	-0.7	-1.1	-0.6	-1.2	-0.7	-1.5	-0.6	-1.3	-0.6	-0.3	0.2
Arm fat mass (right)	0.6	2.3	16.8	-0.8	-1.2	-1.2	-1.2	0.3	-0.7	-0.7	-0.2	-4.1	-0.7	-2.7	-0.8	0.6	-0.4
Number of full brothers	0.6	0.7	4.0	-0.3	-0.2	-0.6	-0.4	-1.0	-0.3	-0.5	-0.7	-2.0	-0.3	-0.0	-1.5	-1.0	-0.1
Emphysema/chronic bronchitis	0.6	0.7	1.2	-1.0	-0.9	-0.7	-0.8	-0.3	-1.1	-0.8	-0.7	-0.5	-0.9	-0.7	-0.9	-0.7	-1.0
Medication for cholesterol	0.6	0.8	6.2	-0.3	-0.8	-0.3	-0.2	-1.2	-1.0	-0.9	-0.8	2.5	-0.5	0.6	0.2	-0.2	-0.5
Eye problems/disorders: Glaucoma	0.6	0.7	1.4	-0.6	-1.1	-0.4	-0.8	-0.3	-1.0	-1.1	-0.6	0.1	-1.0	-0.1	-1.2	-0.8	-1.1
Medication: Atorvastatin	0.6	0.7	1.8	-1.0	-1.4	-0.9	-1.0	-0.3	-0.8	-0.4	-0.7	-0.0	-1.1	-0.9	-0.7	-0.5	-1.3
Schizophrenia vs Biploar Disorder	0.5	0.7	1.4	-0.8	-1.1	-0.5	-0.8	-0.6	-1.2	-0.8	-0.9	0.3	-0.9	-0.3	-0.7	-0.9	-1.1
Alzheimer’s Disease (including proxy)	0.5	0.8	3.5	1.0	1.1	0.5	0.6	-0.3	0.7	0.4	0.5	-1.9	0.9	0.1	0.1	0.6	1.6
Verbal and Numeric Reasoning (VNR)	0.5	1.3	4.3	1.1	0.7	1.1	1.3	0.1	0.7	1.1	0.6	1.9	1.2	2.1	0.8	0.1	0.9
Body Mass Index (BMI) (2010)	0.5	0.6	1.5	0.6	0.5	0.7	0.9	0.4	1.2	1.1	0.6	0.5	0.9	0.7	0.8	0.8	0.9
Hand grip strength (right)	0.5	1.3	6.1	-0.8	-1.4	-0.3	-0.9	0.9	-0.0	0.3	0.2	-2.2	-0.5	-2.5	-0.7	-1.5	-0.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.0	-0.8	-1.0	-0.6	-0.8	-0.4	-0.9	-0.5	-0.7	0.5	-0.9	-0.3	-0.7	-0.0	-1.0
Serious illness, injury or assault to yourself	0.5	0.7	1.8	0.5	0.7	0.9	1.0	0.5	1.3	0.7	0.8	-0.3	1.0	0.4	1.0	0.2	1.2
Supplements: Glucosamine	0.5	0.7	1.7	-0.8	-1.1	-0.6	-0.7	-0.8	-0.8	-0.8	-1.1	0.3	-0.8	-0.9	-0.3	-1.3	-0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	0.9	-0.8	-0.7	-0.8	-0.8	-0.7	-0.6	-0.8	-0.7	0.7	-0.9	-1.0	-0.1	-0.6	-0.8
Impedance of leg (left)	0.5	2.6	4.9	-1.5	-0.6	-1.5	-1.7	-2.0	-2.2	-1.9	-1.9	-0.4	-1.8	-0.6	-1.9	-1.3	-1.5
Had other major operations	0.5	0.6	3.0	-0.6	-0.6	-0.4	-0.4	-1.1	-0.6	-0.6	-1.0	-0.3	-0.5	-0.0	-1.0	-1.7	-0.4
Medication: Simvastatin	0.5	0.7	6.0	-0.4	-0.4	-0.3	-0.6	0.9	-0.2	0.3	0.5	-2.4	-0.3	-0.8	-1.3	0.4	-0.1
Alcohol intake versus 10 years previously	0.5	0.7	1.8	-0.9	-1.1	-1.0	-1.0	0.3	-1.0	-0.0	-0.3	-0.6	-1.0	-1.3	-0.1	0.4	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	4.3	0.9	1.4	1.6	1.1	1.3	2.1	1.8	1.3	-0.1	1.3	1.0	0.4	-0.5	1.2
Birth weight of first child	0.5	0.9	4.4	-0.3	-0.6	-0.2	-0.7	-0.9	-0.3	-0.3	-0.8	-1.7	-0.6	0.0	-2.1	-1.4	-0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.0	0.9	1.1	0.6	0.8	0.3	1.4	0.9	0.6	-0.0	0.8	1.3	-0.2	-0.2	0.9
Forced vital capacity (FVC), Best measure	0.5	2.0	6.0	1.1	0.7	1.7	1.2	1.8	1.7	2.4	1.8	-0.8	1.6	0.8	0.2	-0.3	1.6
Leg fat percentage (right)	0.5	2.0	17.1	-0.7	-0.2	-1.0	-1.0	-0.3	-0.6	-1.3	-0.4	-4.1	-0.5	-1.9	-0.8	1.0	-0.1
Arm fat-free mass (right)	0.5	2.4	7.7	-1.3	-2.5	-1.2	-1.6	0.6	-0.8	-0.1	-0.4	-2.3	-1.3	-2.8	-1.1	-1.8	-1.5
Wheeze or whistling in the chest in last year	0.5	1.0	2.0	0.7	0.1	0.8	0.7	1.1	1.4	1.4	1.2	-1.3	1.1	-0.1	0.6	0.8	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.3	-0.8	-0.8	-0.8	-1.0	-0.4	-0.7	-1.1	-0.6	-0.7	-1.0	-0.8	-0.5	0.4	-1.0
Medication: Ibuprofen	0.5	0.6	2.3	-0.5	-0.2	-1.1	-0.7	-1.5	-0.9	-0.9	-1.2	-0.6	-0.6	-0.3	-0.8	-0.3	-0.4
Arm fat percentage (left)	0.5	1.9	15.6	-0.4	-0.4	-0.9	-0.9	0.5	-0.4	-0.7	0.1	-4.0	-0.4	-2.3	-0.4	1.3	0.1
Mineral and other dietary supplements	0.5	0.7	3.1	0.6	1.8	0.5	0.8	0.3	-0.3	0.2	0.6	0.5	0.8	1.2	0.6	1.4	0.7
Arm fat mass (left)	0.5	2.2	16.7	-0.8	-1.2	-1.2	-1.2	0.4	-0.6	-0.7	-0.2	-4.1	-0.7	-2.6	-0.9	0.6	-0.4
Miserableness	0.5	0.8	4.8	-0.1	-2.2	-1.2	-0.9	-0.7	-0.1	-0.1	-0.8	-0.2	-0.9	-0.2	-1.2	-0.5	-0.9
Guilty feelings	0.5	0.7	2.8	0.3	0.2	-0.3	0.5	-1.7	0.1	-0.7	-0.8	-1.0	0.5	0.9	-0.4	-1.6	0.9
Leg fat percentage (left)	0.5	2.0	17.8	-0.7	-0.1	-0.9	-0.9	-0.2	-0.5	-1.2	-0.3	-4.2	-0.5	-2.0	-0.8	0.9	-0.0
Number of operations (self-reported)	0.5	0.8	3.5	-0.8	-0.5	-0.2	-0.1	-1.9	-0.2	-0.6	-1.2	-0.7	-0.1	0.2	-0.9	-1.8	0.2
Diastolic blood pressure, automated reading	0.5	1.7	10.2	0.3	0.2	0.1	-0.4	1.9	-0.1	-0.1	1.4	-3.2	0.1	-2.0	0.2	1.6	0.7
Lung FVC	0.4	2.2	4.3	1.5	2.1	1.6	1.5	1.2	1.6	1.7	1.6	-0.8	1.8	1.2	0.4	0.7	1.8
Current tobacco smoking	0.4	0.6	5.3	-0.5	0.4	-0.4	-0.1	-0.7	-0.2	-0.5	-0.3	-2.3	0.1	-0.8	-0.4	-0.2	0.5
Multivitamins +/- minerals	0.4	0.6	1.2	-1.0	-1.1	-0.9	-0.7	-0.6	0.1	-0.7	-0.8	-0.1	-0.7	-1.1	-0.3	-0.9	-0.5
Medication: Atenolol	0.4	0.5	3.1	-0.7	1.0	-0.1	-0.5	0.4	-0.2	-0.4	0.2	-1.8	-0.3	-1.4	-0.1	0.5	0.0
Diabetes (self-reported)	0.4	0.6	2.7	0.7	-0.2	0.5	0.6	1.0	0.4	0.9	1.0	-0.6	0.8	0.5	0.4	1.6	0.8
Medication: Ramipril	0.4	0.5	1.3	-0.2	0.6	0.3	0.4	0.8	1.0	0.7	0.7	-0.8	0.6	-0.6	1.1	0.8	0.9
Illnesses of siblings	0.4	0.5	4.1	-0.0	0.1	-0.3	0.1	-0.4	-0.8	0.4	-0.5	2.0	-0.0	1.1	0.3	-0.1	-0.9
Weight	0.4	2.0	12.8	-0.6	-1.8	-1.0	-1.2	0.8	-0.6	-0.1	0.0	-3.6	-0.7	-2.7	-0.8	-0.2	-0.6
Arm fat percentage (right)	0.4	1.6	14.4	-0.2	-0.3	-0.8	-0.6	0.6	-0.3	-0.5	0.3	-3.8	-0.1	-1.9	-0.3	1.7	0.3
Loud music exposure frequency	0.4	0.4	1.5	0.3	-0.3	-0.1	0.6	-0.3	1.2	0.6	0.3	-0.4	0.7	1.0	0.3	0.5	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.2	0.7	-0.7	0.6	0.7	0.8	1.5	1.4	0.7	0.5	0.6	0.2	0.4	-0.2	0.4
Pulse wave peak to peak time	0.4	0.4	1.6	0.6	-0.1	0.5	0.4	0.9	0.4	1.1	0.5	1.2	0.3	1.0	0.2	-0.1	-0.4
Eye problems/disorders: None of the above	0.4	0.4	1.1	-1.0	-0.9	-0.4	-0.3	-0.6	-0.5	-1.0	-0.5	1.0	-0.5	-0.7	0.5	0.3	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.3	-0.5	-0.2	-0.4	-0.7	0.1	-0.9	-0.8	-0.1	-1.5	-0.4	-1.2	-0.0	0.8	-0.1
Arm predicted mass (right)	0.4	2.0	6.5	-1.1	-2.3	-1.1	-1.4	0.8	-0.6	0.1	-0.2	-2.1	-1.1	-2.5	-0.9	-1.8	-1.3
Number of full sisters	0.4	0.4	1.9	-0.2	0.3	0.2	0.3	0.5	-0.2	0.4	0.5	1.4	0.2	-0.3	1.4	1.1	0.2
Medication: Gliclazide	0.4	0.4	1.0	-0.6	-1.0	-0.5	-0.6	-0.4	-0.7	-0.5	-0.5	-1.0	-0.5	-0.4	-0.9	0.4	-0.4
Illnesses of father: None of the above (group 1)	0.4	0.4	0.9	-0.6	-0.3	-0.8	-0.8	-0.9	-0.6	-0.5	-0.9	-0.2	-0.8	-0.2	-0.7	0.2	-0.9
Smoking status: Current	0.4	0.6	4.8	-0.8	0.2	-0.4	-0.4	-0.5	-0.3	-0.6	-0.4	-2.2	-0.2	-1.3	-0.5	-0.6	0.2
High cholesterol (Self-reported)	0.4	0.6	2.7	-0.2	-0.8	-0.4	-0.7	1.1	-0.0	0.7	0.3	-1.6	-0.4	-0.5	-1.5	0.5	-0.6
Medication: Bendroflumethiazide	0.4	0.6	1.8	0.3	0.5	0.2	0.5	1.1	1.3	1.3	1.0	-0.5	0.7	-0.3	0.8	0.1	0.9
Risk taking	0.4	0.6	4.6	-0.2	-0.2	-0.0	0.3	0.2	1.2	0.3	0.2	2.1	0.2	0.8	1.0	0.2	-0.2
Fractured/broken bones in last 5 years	0.4	0.5	2.1	0.7	-0.4	0.5	0.2	1.4	1.2	0.9	0.9	-0.3	0.3	-0.2	0.2	0.3	0.1
Bipolar Disorder (2018)	0.3	0.4	0.9	0.6	0.8	0.7	0.7	0.2	0.4	0.5	0.5	-0.0	0.7	0.3	0.9	0.9	1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	2.2	-0.3	-0.0	-0.5	-0.4	-0.0	0.1	-0.3	0.2	0.0	-0.3	-1.5	0.7	0.9	0.2
Lung FEV1/FVC ratio	0.3	1.7	3.5	-1.4	1.6	-1.1	-0.9	-1.9	1.8	-1.8	-1.6	-0.3	-1.1	-0.2	-0.6	-1.5	-1.0
Hand grip strength (left)	0.3	0.9	3.5	-0.1	-0.6	0.3	-0.1	1.0	0.9	0.8	0.7	-1.9	0.2	-1.5	-0.3	-1.9	0.4
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.1	0.9	0.7	0.5	0.9	-0.1	1.0	0.9	0.2	0.2	0.8	0.9	0.3	-0.1	0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.9	0.7	0.5	0.1	0.5	0.1	0.6	0.7	0.4	-1.4	0.7	0.8	-0.5	-0.3	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	2.4	-0.1	-0.4	-0.7	-0.4	0.5	0.7	0.2	0.1	-1.5	-0.2	-0.9	-0.3	0.2	-0.2
Vitamin and mineral supplements	0.3	0.4	1.1	0.7	0.9	0.8	0.6	-0.0	-0.5	0.2	0.3	0.7	0.5	1.1	0.3	0.3	0.4
Leg fat-free mass (left)	0.3	1.4	5.1	-0.5	-2.1	-0.6	-0.8	1.3	-0.6	0.5	0.3	-2.2	-0.5	-2.2	-0.3	-0.5	-0.6
Townsend deprivation index at recruitment	0.3	0.4	2.2	-0.2	-0.1	0.0	-0.1	0.4	0.5	0.2	0.4	-1.5	0.2	-0.3	0.1	1.5	0.5
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.9	-0.8	-0.8	-0.2	-0.5	-0.6	-0.7	-1.0	-0.8	0.0	-0.6	0.1	-0.6	0.1	-0.7
Body mass index (BMI)	0.3	1.1	9.1	0.3	0.4	-0.1	0.0	0.8	0.9	-0.1	0.7	-3.0	0.5	-1.3	0.2	1.4	0.6
Leg predicted mass (left)	0.3	1.4	5.2	-0.6	-2.2	-0.7	-0.9	1.2	-0.6	0.5	0.3	-2.1	-0.6	-2.3	-0.3	-0.6	-0.7
Waist circumference	0.3	1.2	13.8	-0.1	-0.3	-0.3	-0.2	0.2	0.5	-0.2	0.3	-3.7	0.2	-1.3	-0.5	0.5	0.6
Hair/balding pattern: Pattern 2	0.3	0.3	1.2	-0.5	-0.8	-0.7	-0.6	0.1	-0.6	-0.1	-0.3	0.2	-0.7	-1.1	-0.3	-0.3	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.7	0.2	-0.6	0.2	0.4	-0.3	1.1	0.7	-0.0	-0.3	0.5	0.2	0.3	-1.3	0.6
Financial difficulties in last 2 years	0.3	0.4	1.7	-0.7	0.2	-0.2	0.2	-1.0	0.3	-0.4	-0.3	-1.3	0.3	-0.8	0.7	-0.4	1.2
Heart attack	0.3	0.4	2.4	0.1	0.6	0.4	0.5	-0.1	1.6	0.2	0.2	0.2	0.5	0.0	0.6	-0.7	1.0
Hip circumference	0.3	1.2	12.2	0.6	-1.1	-0.6	-0.2	0.4	0.1	0.2	0.4	-3.5	0.3	-1.3	-0.6	0.6	0.6
Father’s age at death	0.3	0.4	1.8	0.5	-0.2	0.3	0.5	0.4	0.9	1.4	0.4	1.3	0.5	0.2	0.6	-0.2	0.3
Hair/balding pattern: Pattern 3	0.3	0.5	2.3	0.4	1.5	0.5	0.3	-0.6	-0.3	-0.2	0.0	-1.3	0.4	0.2	-0.2	-0.2	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.6	-0.2	0.6	0.1	0.2	-0.9	-0.0	-0.7	-0.5	-0.1	0.1	0.6	-0.5	-1.3	0.1
Medication: Cholesterol lowering	0.3	0.5	2.7	-0.1	-0.3	-0.2	-0.4	0.9	0.7	0.6	0.6	-1.6	-0.0	-0.3	-1.1	0.3	0.1
Supplements: Vitamin C	0.3	0.3	2.2	-0.0	0.8	-0.4	-0.1	-0.2	0.6	0.4	-0.0	-1.5	0.0	-0.1	-0.8	0.3	0.2
Illnesses of siblings: Diabetes	0.3	0.3	1.2	0.5	1.1	0.4	0.5	0.2	1.1	-0.0	0.5	-0.5	0.4	0.1	0.2	-0.3	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	2.0	0.4	-0.3	0.7	0.6	1.0	1.0	1.4	0.8	0.7	0.5	0.6	0.6	-0.2	0.4
Whole body fat-free mass	0.3	1.5	5.4	-0.7	-2.3	-0.7	-1.0	1.2	-0.6	0.6	0.2	-1.9	-0.8	-2.3	-0.5	-1.1	-1.0
Breast cancer (self-reported)	0.3	0.4	2.5	-0.3	-0.3	-0.6	-0.3	-0.8	-0.8	-0.1	-0.4	-1.6	-0.2	-0.1	-0.8	-0.6	0.1
Financial situation satisfaction	0.3	0.4	1.8	0.3	-0.1	0.1	0.5	-0.1	1.3	0.7	0.3	-1.2	0.7	0.1	0.3	-0.3	1.0
Illnesses of father: High blood pressure	0.3	0.4	2.1	-0.7	-0.1	-0.5	-0.7	0.6	-0.0	-0.4	0.1	-1.1	-0.6	-1.4	-0.0	0.1	-0.3
Basal metabolic rate	0.3	1.7	6.2	-0.7	-2.2	-0.8	-1.1	1.2	-0.7	0.4	0.2	-2.3	-0.8	-2.5	-0.5	-0.9	-0.9
Arm fat-free mass (left)	0.3	1.4	5.0	-0.6	-1.9	-0.7	-0.9	1.1	-0.5	0.5	0.2	-2.2	-0.7	-2.0	-0.7	-1.1	-0.9
Average weekly beer plus cider intake	0.3	0.4	3.0	-0.3	-1.7	-0.4	-0.4	0.4	0.2	0.1	0.0	-0.5	-0.5	-0.5	-0.6	-0.6	-0.6
Ever depressed for a whole week	0.3	0.4	2.6	0.1	-0.8	0.3	0.3	-0.9	0.8	0.3	-0.5	0.6	0.1	0.2	0.2	-1.6	0.1
Myopia	0.3	0.4	2.7	0.3	0.5	0.7	0.6	-0.6	0.5	0.4	-0.1	0.5	0.5	1.6	-0.4	-0.6	0.6
Cholesterol lowering medication	0.3	0.5	1.6	-0.8	-0.6	-0.6	-0.7	-0.2	-0.8	-0.5	-0.4	-1.2	-0.6	-0.6	-0.9	-0.1	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.5	0.2	0.5	0.4	0.4	0.1	1.6	0.2	0.3	0.3	0.4	-0.0	0.6	-0.6	0.9
Heart disease (siblings)	0.3	0.4	1.5	-0.2	-0.9	-0.4	-0.6	-0.5	-0.3	-0.6	-0.6	-0.9	-0.6	-0.4	-1.2	-0.8	-0.4
Arm predicted mass (left)	0.3	1.3	4.5	-0.7	-2.0	-0.7	-0.9	0.9	-0.5	0.5	0.1	-2.1	-0.6	-1.9	-0.7	-1.2	-0.8
Depression (Nagel 2018)	0.2	0.2	0.8	0.4	0.4	-0.2	0.3	-0.2	0.9	0.5	0.0	-0.7	0.3	-0.1	0.2	-0.8	0.8
Schizophrenia (2018)	0.2	0.4	1.0	-0.6	-0.4	-0.2	-0.7	0.0	-1.0	-0.1	-0.5	0.4	-0.8	-0.9	0.2	0.9	-0.8
Ovarian Cancer	0.2	0.3	1.6	-0.4	0.3	-0.1	-0.1	-0.8	-0.4	-1.2	-0.6	0.2	-0.3	-0.4	0.2	-0.7	0.2
Bipolar Disorder (2011)	0.2	0.2	0.6	-0.5	-0.7	-0.4	-0.4	-0.6	-0.0	0.1	-0.3	0.0	-0.4	-0.8	0.3	0.5	-0.0
Coronary Artery Disease (CAD)	0.2	0.2	1.1	-0.1	-0.7	-0.1	-0.2	1.1	-0.2	0.7	0.6	0.0	-0.1	-0.4	0.6	0.5	-0.3
Primary Biliary Cirrhosis	0.2	0.3	1.5	0.1	0.4	0.2	0.1	0.4	-0.6	-0.6	0.2	1.2	-0.1	0.6	0.2	0.6	-0.5
Schizophrenia (2014)	0.2	0.5	1.0	-0.8	-1.0	-0.1	-0.6	-0.4	-0.9	-0.7	-0.7	0.9	-0.9	-1.0	0.3	-0.0	-0.8
BMI	0.2	1.1	7.8	-0.4	0.2	-0.9	-0.5	-0.1	0.9	-1.1	-0.2	-2.8	-0.2	-1.9	0.1	0.8	0.1
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.2	-0.5	-0.6	-0.5	-0.5	0.4	-0.2	0.2	0.2	-1.0	-0.3	-1.1	0.3	0.9	-0.1
Average weekly spirits intake	0.2	0.2	0.9	0.9	0.1	0.2	0.2	0.7	0.2	0.4	0.6	-0.8	0.3	0.2	-0.1	-0.6	0.3
Angina	0.2	0.3	1.2	0.1	1.1	0.2	0.2	0.8	0.4	0.1	0.6	-0.6	0.2	-0.2	0.2	0.9	0.4
Age when periods started (menarche)	0.2	0.4	1.2	0.5	-0.4	0.6	0.7	0.6	0.5	1.1	0.6	0.6	0.7	0.2	0.6	0.4	0.8
Nervous feelings	0.2	0.4	2.8	-0.2	-1.7	-0.5	-0.4	-0.1	-0.4	-0.0	-0.3	0.3	-0.4	-0.8	0.3	0.5	-0.4
Hearing difficulty/problems with background noise	0.2	0.4	1.8	0.3	-0.2	0.3	0.6	-0.6	1.2	0.2	-0.3	0.8	0.4	1.3	0.3	-0.5	0.0
Forced vital capacity (FVC)	0.2	0.7	2.3	0.3	-0.2	0.7	0.2	1.4	0.5	1.5	1.1	-1.4	0.5	-0.4	-0.5	-0.7	0.7
Impedance of arm (right)	0.2	0.8	4.2	-0.4	-0.9	-0.8	-0.8	-0.9	-2.0	-0.8	-0.9	0.4	-0.9	-0.1	-0.7	0.3	-0.6
Trunk fat-free mass	0.2	1.3	5.3	-0.6	-2.3	-0.6	-0.9	1.2	-0.5	0.8	0.2	-1.4	-0.7	-2.1	-0.4	-1.3	-1.0
Time employed in main current job	0.2	0.3	2.1	0.2	-0.3	0.3	0.3	-0.1	0.2	0.5	-0.1	0.7	0.1	1.4	-0.6	0.6	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.6	0.2	0.8	0.9	0.4	1.1	1.3	1.2	0.8	-0.6	0.6	0.0	-0.2	-0.7	0.6
Lung cancer (father)	0.2	0.2	1.4	-0.6	0.5	0.2	-0.2	-0.6	-0.2	-0.6	-0.4	-1.2	-0.1	-0.1	-0.4	0.7	0.0
Trunk predicted mass	0.2	1.3	5.2	-0.6	-2.3	-0.5	-0.9	1.2	-0.5	0.8	0.2	-1.4	-0.7	-2.1	-0.4	-1.3	-1.0
Length of working week for main job	0.2	0.2	0.6	-0.1	0.7	0.1	-0.1	0.3	0.0	0.6	0.2	-0.5	-0.0	-0.8	0.5	0.5	0.2
Exposure to tobacco smoke at home	0.2	0.3	1.0	-0.2	-0.1	-0.3	-0.4	-0.7	-0.8	-0.9	-0.4	-1.0	-0.3	-0.3	-0.5	-0.2	0.2
Tense / ‘highly strung’	0.2	0.4	1.4	-0.6	-1.2	-0.6	-0.5	-0.9	-0.3	0.2	-0.7	-0.5	-0.4	-0.9	0.1	-0.2	-0.1
Peak expiratory flow (PEF)	0.2	0.4	2.6	-0.2	-0.1	0.1	-0.3	0.6	1.6	0.6	0.2	-0.3	-0.2	-0.2	-0.8	-1.1	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.3	0.3	-0.0	-0.0	0.1	-0.8	-0.7	-0.9	-0.7	1.1	-0.3	1.0	-0.2	-0.3	-0.8
Glaucoma (self-reported)	0.2	0.3	1.1	-0.3	-0.6	0.0	-0.3	-0.2	-0.6	-0.6	-0.4	-0.0	-0.4	0.2	-0.8	-1.1	-0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	0.3	-0.3	-0.1	0.2	0.3	0.8	0.4	0.4	-0.5	0.3	-0.6	0.7	-0.6	0.6
Angina (self-reported)	0.2	0.3	1.2	0.1	1.1	0.1	0.1	0.6	0.3	0.1	0.4	-0.9	0.1	-0.3	-0.0	0.8	0.4
Had major operations	0.2	0.2	0.9	-0.3	-0.6	0.0	0.3	-1.0	0.2	-0.1	-0.6	0.6	0.2	0.7	0.2	-0.3	0.1
Smoking status: Previous	0.2	0.3	1.5	0.0	-0.1	0.7	0.4	0.3	1.2	0.9	0.4	0.1	0.4	0.2	0.3	0.6	0.5
Leg fat-free mass (right)	0.2	1.1	3.8	-0.3	-1.8	-0.4	-0.6	1.5	-0.3	0.8	0.5	-1.8	-0.4	-2.0	-0.1	-0.6	-0.5
Diabetes diagnosed by doctor	0.2	0.4	2.6	0.2	-0.6	-0.1	-0.0	0.7	0.0	0.7	0.6	-0.9	0.2	-0.1	0.1	1.6	0.2
Eye problems/disorders: Cataract	0.2	0.2	1.3	0.3	-0.3	-0.4	-0.4	-0.2	-0.3	0.5	-0.3	-1.1	-0.2	-0.3	-0.6	-0.5	-0.3
Back pain experienced in last month	0.2	0.3	1.0	1.0	0.2	0.2	0.1	0.9	-0.0	0.5	0.6	0.8	0.2	0.1	0.4	1.0	0.1
Whole body water mass	0.2	1.4	5.0	-0.6	-2.2	-0.7	-0.9	1.3	-0.6	0.7	0.2	-1.8	-0.7	-2.2	-0.4	-1.1	-0.9
Leg predicted mass (right)	0.2	1.1	4.1	-0.3	-1.9	-0.4	-0.6	1.5	-0.4	0.8	0.5	-1.9	-0.4	-2.0	-0.1	-0.6	-0.5
Average weekly champagne plus white wine intake	0.2	0.3	1.5	0.4	0.3	0.4	0.4	0.1	0.3	0.1	0.1	1.2	0.2	1.2	0.0	0.1	-0.0
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.9	-0.3	0.2	0.2	0.2	0.2	1.0	0.5	0.2	0.4	0.1	-0.3	0.8	0.2	0.3
Supplements: Calcium	0.2	0.2	1.7	0.5	-0.9	0.3	0.2	-0.1	0.1	0.0	-0.0	1.3	-0.1	0.4	0.6	-0.0	-0.1
Bipolar Disorder or Schizophrenia	0.1	0.2	1.1	-0.1	-0.1	0.3	-0.1	0.1	-0.5	0.3	-0.1	0.1	-0.2	-0.7	0.7	1.0	-0.0
Heel T-Score	0.1	0.8	2.6	0.5	1.4	0.3	0.9	0.5	1.6	0.1	0.6	1.2	0.8	1.1	0.8	0.6	0.4
Waist Hip Ratio (WHR)	0.1	0.7	3.5	-1.9	0.4	-0.3	-0.7	-0.3	0.2	-0.5	-0.4	-1.3	-0.7	-1.5	-0.2	-0.0	-0.3
Chronotype (morning person)	0.1	0.3	1.3	-0.6	0.5	-0.4	-0.4	-0.7	-1.0	-1.2	-0.5	-0.2	-0.3	-0.7	0.1	0.2	0.2
Hair Pigment	0.1	3.6	5.9	1.4	2.4	2.2	2.1	1.9	2.1	2.0	2.1	-0.2	2.3	1.3	1.6	1.4	2.4
Diabetes (mother)	0.1	0.2	0.6	-0.1	0.5	-0.3	-0.2	-0.4	0.5	-0.4	-0.4	-0.8	-0.2	-0.1	-0.6	-0.6	-0.2
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	0.1	0.2	0.5	0.4	-0.2	0.0	0.4	0.1	0.1	0.5	0.6	0.1	0.0	0.7
Past tobacco smoking	0.1	0.2	0.8	0.3	-0.1	-0.5	-0.1	-0.1	-0.8	-0.5	-0.2	0.9	-0.2	0.3	0.2	0.0	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.1	-0.1	-0.5	0.0	0.0	-0.2	0.8	0.6	-0.0	-0.5	0.1	-1.1	0.4	-0.1	0.6
Hair/balding pattern: Pattern 4	0.1	0.2	1.2	0.3	0.2	0.5	0.3	0.5	0.5	-0.0	0.4	-0.6	0.4	-0.1	0.3	1.1	0.4
Pulse wave reflection index	0.1	0.1	0.6	0.1	0.4	0.3	0.4	-0.1	0.8	-0.1	0.1	-0.0	0.3	-0.2	0.5	0.3	0.6
Number of children fathered	0.1	0.1	0.4	-0.4	0.1	-0.3	-0.3	-0.4	0.3	-0.6	-0.4	0.4	-0.3	0.2	-0.4	-0.0	-0.4
Overall health rating	0.1	0.3	2.7	0.2	0.1	-0.3	-0.0	0.0	0.2	-0.1	0.2	-1.6	0.2	-0.4	-0.3	0.9	0.6
Ever had bowel cancer screening	0.1	0.2	0.9	-0.3	-0.5	-0.3	-0.0	-0.9	-0.3	-0.5	-0.5	0.1	-0.0	0.4	-0.3	-0.2	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	1.0	-0.0	0.2	-0.1	0.0	-0.0	0.6	0.2	-0.1	0.1	-0.2	-0.5	0.2	-1.0	-0.1
Age started oral contraceptive pill	0.1	0.1	0.6	-0.2	-0.2	-0.5	-0.2	-0.3	-0.8	-0.2	-0.4	-0.4	-0.2	-0.2	-0.1	-0.6	-0.4
Tanning	0.0	0.4	1.4	-0.5	0.1	-0.7	-0.6	-0.8	-0.1	-0.9	-0.8	-0.2	-0.7	0.4	-1.2	-0.2	-0.9
Diabetes (father)	0.0	0.0	0.4	0.0	0.1	0.1	0.3	-0.1	0.0	-0.2	-0.0	0.2	0.2	0.6	0.2	0.1	0.0

Hub : Genes

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Trait associations