[Hub]/) : Traits : Qualifications: A levels/AS levels or equivalent :

chr10:64,195,778-65,606,229

Best TWAS P=1.35e-08 · Best GWAS P=8.92e-09 conditioned to 0.0599

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Frontal Cortex BA9 NRBF2 0.25 0.17 lasso 6 0.16 6.1e-05 5.4 -5.3 9.3e-08 -0.88 0.03 0.95 FALSE
2 GTEx Nerve Tibial NRBF2 0.08 0.09 enet 11 0.06 5.0e-05 4.9 -5.7 1.4e-08 -0.83 0.04 0.96 TRUE
3 GTEx Thyroid NRBF2 0.11 0.05 lasso 3 0.07 2.5e-06 -3.2 -5.6 2.6e-08 -0.66 0.05 0.94 FALSE
4 ROSMAP Brain Pre-frontal Cortex NRBF2 0.34 0.46 lasso 5 0.46 3.1e-66 5.4 -5.2 1.7e-07 -0.89 0.02 0.98 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma NRBF2 0.05 0.06 lasso 2 0.06 5.5e-12 5.4 -5.4 5.5e-08 -0.89 0.00 1.00 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme JMJD1C 0.11 0.02 blup 87 0.05 1.4e-02 5.3 -5.6 2.8e-08 -0.80 0.02 0.66 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme NRBF2 0.17 0.09 enet 10 0.13 1.1e-04 5.4 -5.4 7.9e-08 -0.80 0.00 0.94 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma NRBF2 0.08 0.08 enet 6 0.08 4.3e-09 5.4 -5.2 2.1e-07 -0.90 0.00 1.00 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma NRBF2 0.18 0.13 enet 11 0.08 2.5e-04 5.3 -5.4 7.3e-08 -0.87 0.00 0.99 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma NRBF2 0.14 0.10 enet 16 0.09 8.1e-09 5.3 -5.3 1.4e-07 -0.89 0.00 1.00 FALSE