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chr11:94,805,896-96,276,010

Best TWAS P=2.87e-13 · Best GWAS P=1.13e-12 conditioned to 0.382

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM76B	0.06	0.02	lasso	3	0.01	8.1e-03	6.3	-6.6	5.5e-11	-0.90	0.07	0.92	FALSE
2	GTEx	Adipose Subcutaneous	CEP57	0.17	0.12	enet	26	0.14	3.1e-11	6.8	7.2	4.3e-13	0.91	0.03	0.97	FALSE
3	GTEx	Adipose Subcutaneous	AP001877.1	0.16	0.04	enet	35	0.05	1.0e-04	6.3	5.6	1.9e-08	0.59	0.06	0.93	FALSE
4	GTEx	Adipose Visceral Omentum	CEP57	0.10	0.16	lasso	1	0.13	3.3e-07	6.9	6.9	4.0e-12	0.99	0.01	0.99	FALSE
5	GTEx	Artery Tibial	MTMR2	0.17	0.09	enet	23	0.11	1.2e-08	6.6	-6.2	7.2e-10	-0.75	0.02	0.98	FALSE
6	GTEx	Brain Caudate basal ganglia	AP001877.1	0.21	0.03	lasso	15	0.01	1.4e-01	6.8	6.4	1.9e-10	0.89	0.03	0.83	FALSE
7	GTEx	Brain Cerebellar Hemisphere	AP001877.1	0.29	0.24	lasso	7	0.25	5.0e-07	7.1	7.0	3.5e-12	0.96	0.04	0.96	FALSE
8	GTEx	Brain Frontal Cortex BA9	AP001877.1	0.20	-0.01	enet	21	0.00	4.6e-01	6.3	5.2	1.9e-07	0.73	0.05	0.55	FALSE
9	GTEx	Brain Putamen basal ganglia	AP001877.1	0.39	0.05	lasso	15	0.08	6.5e-03	6.8	5.5	3.6e-08	0.78	0.04	0.77	FALSE
10	GTEx	Breast Mammary Tissue	CEP57	0.11	0.06	lasso	3	0.06	4.5e-04	6.6	6.7	2.8e-11	0.93	0.03	0.95	FALSE
11	GTEx	Breast Mammary Tissue (Male)	CEP57	0.08	0.06	lasso	2	0.03	5.8e-02	6.2	6.2	5.7e-10	0.82	0.05	0.47	FALSE
12	GTEx	Breast Mammary Tissue (Female)	CEP57	0.01	0.01	lasso	2	-0.01	7.0e-01	5.7	6.3	2.3e-10	0.87	0.04	0.42	FALSE
13	GTEx	Colon Transverse	CEP57	0.12	0.11	lasso	3	0.11	6.8e-06	6.3	6.9	7.0e-12	0.96	0.02	0.97	FALSE
14	GTEx	Esophagus Mucosa	CEP57	0.14	0.14	lasso	3	0.10	6.0e-07	6.3	6.7	2.1e-11	0.89	0.06	0.94	FALSE
15	GTEx	Esophagus Mucosa	AP001877.1	0.09	0.00	lasso	3	0.00	5.4e-01	7.1	7.3	2.9e-13	0.93	0.02	0.83	TRUE
16	GTEx	Esophagus Muscularis	CEP57	0.15	0.05	enet	21	0.06	9.0e-05	6.3	6.8	8.9e-12	0.85	0.05	0.95	FALSE
17	GTEx	Esophagus Muscularis	AP001877.1	0.17	0.09	lasso	6	0.10	6.2e-07	6.3	6.4	1.3e-10	0.87	0.13	0.86	FALSE
18	GTEx	Liver	FAM76B	0.43	0.08	enet	32	0.13	1.4e-04	6.8	5.3	1.2e-07	0.73	0.04	0.92	FALSE
19	GTEx	Liver	CEP57	0.24	0.10	enet	23	0.01	2.1e-01	6.8	7.1	1.4e-12	0.92	0.03	0.86	FALSE
20	GTEx	Lung	CEP57	0.12	0.05	enet	16	0.04	4.4e-04	7.1	7.0	1.8e-12	0.92	0.04	0.96	FALSE
21	GTEx	Muscle Skeletal	CEP57	0.15	0.18	lasso	9	0.18	1.8e-17	6.7	6.5	7.0e-11	0.93	0.05	0.95	FALSE
22	GTEx	Nerve Tibial	MTMR2	0.14	0.10	enet	16	0.08	2.0e-06	7.1	-7.3	3.9e-13	-0.95	0.03	0.97	FALSE
23	GTEx	Nerve Tibial	CEP57	0.15	0.08	lasso	6	0.07	1.9e-05	6.3	6.6	3.5e-11	0.92	0.04	0.96	FALSE
24	GTEx	Nerve Tibial	AP001877.1	0.15	0.05	lasso	3	0.05	1.6e-04	6.8	7.1	9.0e-13	0.92	0.04	0.96	FALSE
25	GTEx	Pancreas	CEP57	0.19	0.10	lasso	13	0.08	3.6e-04	6.3	6.8	1.3e-11	0.91	0.06	0.94	FALSE
26	GTEx	Skin Not Sun Exposed Suprapubic	CEP57	0.14	0.06	enet	10	0.05	9.6e-04	5.3	6.7	2.2e-11	0.84	0.04	0.96	FALSE
27	GTEx	Skin Sun Exposed Lower leg	CEP57	0.19	0.14	enet	24	0.16	4.1e-13	6.3	6.8	1.2e-11	0.92	0.05	0.95	FALSE
28	GTEx	Small Intestine Terminal Ileum	AP001877.1	0.34	0.14	lasso	22	0.11	1.8e-03	6.2	6.5	6.2e-11	0.88	0.04	0.85	FALSE
29	GTEx	Testis	MTMR2	0.22	0.18	lasso	3	0.18	2.8e-08	6.6	-6.9	5.7e-12	-0.97	0.02	0.98	FALSE
30	GTEx	Thyroid	CEP57	0.11	0.01	enet	15	0.03	1.8e-03	6.3	6.8	1.2e-11	0.73	0.06	0.88	FALSE
31	METSIM	Adipose	CEP57	0.06	0.07	lasso	1	0.06	1.8e-09	6.2	6.2	5.0e-10	0.85	0.04	0.96	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	AP001877.1	0.17	0.27	lasso	12	0.27	3.6e-35	6.8	6.8	1.3e-11	0.95	0.07	0.93	FALSE
33	YFS	Blood	CEP57	0.04	0.03	lasso	5	0.03	3.4e-11	6.8	5.4	6.2e-08	0.85	0.05	0.95	FALSE
34	YFS	Blood	FAM76B	0.14	0.25	lasso	10	0.26	8.1e-83	6.7	-6.8	1.5e-11	-0.94	0.07	0.93	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP57	0.02	0.00	blup	53	0.01	6.0e-02	6.3	6.1	1.3e-09	0.90	0.02	0.59	FALSE