Best TWAS P=2.61e-30 · Best GWAS P=1.43e-32 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ALDH9A1 | 0.17 | 0.17 | lasso | 3 | 0.12 | 2.1e-07 | 4.4 | -5.4 | 5.8e-08 | -0.50 | 0.88 | 0.11 | FALSE |
| 2 | GTEx | Artery Tibial | ALDH9A1 | 0.36 | 0.31 | enet | 28 | 0.35 | 5.2e-28 | 4.4 | -5.3 | 9.1e-08 | -0.44 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Artery Tibial | TMCO1 | 0.15 | 0.02 | lasso | 4 | 0.01 | 4.5e-02 | 11.8 | -11.4 | 2.6e-30 | -0.97 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Colon Sigmoid | ALDH9A1 | 0.41 | 0.18 | lasso | 8 | 0.26 | 7.4e-10 | 4.4 | -5.7 | 1.4e-08 | -0.53 | 0.39 | 0.59 | FALSE |
| 5 | GTEx | Lung | ALDH9A1 | 0.19 | 0.10 | enet | 24 | 0.17 | 6.5e-13 | 4.4 | -5.7 | 1.4e-08 | -0.52 | 0.97 | 0.02 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ALDH9A1 | 0.08 | 0.03 | enet | 11 | 0.07 | 2.6e-08 | 5.0 | -5.4 | 6.6e-08 | -0.52 | 0.33 | 0.48 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ALDH9A1 | 0.14 | 0.09 | enet | 13 | 0.09 | 6.8e-10 | 4.4 | -5.8 | 7.9e-09 | -0.50 | 1.00 | 0.00 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | ALDH9A1 | 0.20 | 0.06 | enet | 12 | 0.13 | 9.4e-13 | 4.4 | -6.2 | 7.8e-10 | -0.48 | 1.00 | 0.00 | FALSE |