Best TWAS P=1.08e-09 · Best GWAS P=1.13e-06 conditioned to 0.538
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SDCCAG8 | 0.06 | 0.04 | blup | 115 | 0.04 | 2.0e-08 | 4.3 | -5.2 | 1.5e-07 | -0.84 | 0.01 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SDCCAG8 | 0.11 | 0.04 | blup | 114 | 0.06 | 1.1e-07 | 4.5 | -6.1 | 1.1e-09 | -0.73 | 0.02 | 0.94 | TRUE |
3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | SDCCAG8 | 0.30 | 0.06 | blup | 113 | 0.12 | 8.0e-04 | -4.3 | -5.3 | 1.2e-07 | -0.61 | 0.02 | 0.53 | FALSE |