[Hub]/) : Traits : Mouth/teeth dental problems :

chr1:154,401,972-155,887,772

Best TWAS P=5.19e-08 · Best GWAS P=1.4e-07 conditioned to 0.0972

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial GBAP1 0.21 0.26 lasso 7 0.26 1.3e-20 4.9 5.1 3.1e-07 0.72 0.05 0.94 FALSE
2 GTEx Brain Cerebellum THBS3 0.17 0.15 enet 6 0.16 2.0e-05 5.1 -5.4 5.2e-08 -0.77 0.03 0.94 TRUE
3 GTEx Brain Cerebellum EFNA1 0.20 0.09 enet 13 0.06 9.2e-03 -5.2 5.3 1.1e-07 0.79 0.02 0.93 FALSE
4 GTEx Cells Transformed fibroblasts SLC50A1 0.08 0.07 lasso 6 0.07 3.9e-06 -5.2 -5.3 1.4e-07 -0.82 0.03 0.97 FALSE
5 GTEx Prostate GBAP1 0.47 0.30 lasso 7 0.32 1.1e-08 4.9 5.2 1.9e-07 0.66 0.04 0.95 FALSE
6 GTEx Small Intestine Terminal Ileum GBAP1 0.20 0.13 lasso 10 0.11 1.8e-03 -5.2 5.4 7.8e-08 0.72 0.03 0.81 FALSE
7 GTEx Spleen THBS3 0.23 0.10 enet 17 0.08 4.6e-03 -4.5 -5.4 7.9e-08 -0.84 0.03 0.85 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM46 0.03 0.00 blup 33 0.02 3.6e-03 -4.0 -5.2 2.1e-07 -0.70 0.01 0.53 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma THBS3 0.02 0.03 lasso 4 0.03 2.1e-04 4.9 -5.1 2.8e-07 -0.63 0.02 0.95 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma GBAP1 0.03 0.01 blup 26 0.02 1.9e-03 -5.2 5.4 8.2e-08 0.70 0.01 0.96 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma RAG1AP1 0.07 0.05 blup 77 0.05 3.8e-06 -4.7 -5.3 1.4e-07 -0.83 0.03 0.96 FALSE