Best TWAS P=5.47e-08 · Best GWAS P=7.31e-07 conditioned to 0.639
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SNX11 | 0.14 | 0.10 | lasso | 9 | 0.12 | 2.6e-10 | 4.6 | -5.3 | 8.9e-08 | -0.32 | 0.07 | 0.91 | FALSE |
| 2 | GTEx | Nerve Tibial | SNX11 | 0.24 | 0.18 | lasso | 7 | 0.21 | 5.3e-15 | 4.6 | -5.2 | 2.5e-07 | -0.39 | 0.07 | 0.91 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RP11-6N17.3 | 0.06 | 0.02 | lasso | 6 | 0.06 | 2.1e-05 | 4.8 | -5.3 | 1.3e-07 | -0.71 | 0.02 | 0.94 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SNX11 | 0.07 | 0.07 | blup | 53 | 0.08 | 1.4e-09 | 4.6 | -5.4 | 5.5e-08 | -0.43 | 0.01 | 0.97 | TRUE |