[Hub]/) : Traits : Mouth/teeth dental problems: Dentures :

chr19:48,464,978-49,935,001

Best TWAS P=1.43e-09 · Best GWAS P=5.07e-08 conditioned to 0.904

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts RASIP1 0.19 0.14 lasso 6 0.20 6.1e-15 4.9 5.2 2.1e-07 0.93 0.04 0.96 FALSE
2 GTEx Esophagus Mucosa RASIP1 0.13 0.13 lasso 4 0.13 9.0e-09 -4.5 5.2 2.1e-07 0.78 0.19 0.80 FALSE
3 GTEx Heart Atrial Appendage MAMSTR 0.24 0.13 lasso 2 0.13 1.3e-06 -5.1 5.4 8.1e-08 0.74 0.03 0.96 FALSE
4 GTEx Heart Left Ventricle MAMSTR 0.26 0.18 lasso 6 0.21 3.4e-11 -5.2 5.5 4.9e-08 0.80 0.04 0.96 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic NTN5 0.19 0.07 lasso 5 0.08 2.5e-05 5.2 5.5 5.0e-08 0.94 0.02 0.97 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma FUT2 0.18 0.22 enet 12 0.18 6.8e-11 5.2 -5.3 1.4e-07 -0.95 0.01 0.99 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FUT2 0.10 0.01 blup 51 0.05 9.8e-04 5.3 -5.3 1.2e-07 -0.88 0.01 0.92 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma FUT2 0.02 0.04 lasso 1 0.03 1.8e-04 -5.1 -5.1 2.6e-07 -0.67 0.04 0.77 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma NTN5 0.05 0.04 lasso 2 0.02 6.7e-04 5.4 5.4 5.1e-08 1.00 0.01 0.99 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FUT2 0.05 0.08 lasso 2 0.08 6.7e-09 5.3 -5.4 7.4e-08 -0.96 0.01 0.99 FALSE
11 The Cancer Genome Atlas Rectum Adenocarcinoma FUT2 0.26 0.28 lasso 10 0.22 5.2e-06 5.4 -5.5 3.3e-08 -0.99 0.01 0.98 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma FUT2 0.14 0.16 lasso 8 0.14 4.9e-10 4.9 -5.1 2.8e-07 -0.95 0.02 0.97 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma NTN5 0.11 0.07 blup 43 0.09 2.6e-09 5.3 6.1 1.4e-09 0.89 0.01 0.99 TRUE