TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Vascular/heart problems diagnosed by doctor
:
←
→
chr2:36,778,887-38,245,716
Best TWAS P=4.46e-09 · Best GWAS P=3.84e-08 conditioned to 1
36.8M
37M
37.2M
37.4M
37.6M
37.8M
38M
38.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
PRKD3
0.08
0.04
lasso
3
0.04
3.0e-05
-5.4
-5.9
4.5e-09
0.98
0.01
0.99
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
PRKD3
0.09
0.08
lasso
2
0.07
6.4e-09
-5.4
-5.4
6.1e-08
0.98
0.00
0.99
FALSE