Best TWAS P=4.46e-09 · Best GWAS P=3.84e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PRKD3 | 0.08 | 0.04 | lasso | 3 | 0.04 | 3.0e-05 | -5.4 | -5.9 | 4.5e-09 | 0.98 | 0.01 | 0.99 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | PRKD3 | 0.09 | 0.08 | lasso | 2 | 0.07 | 6.4e-09 | -5.4 | -5.4 | 6.1e-08 | 0.98 | 0.00 | 0.99 | FALSE |