Best TWAS P=1.4e-08 · Best GWAS P=1.22e-06 conditioned to 0.5
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | NCOA1 | 0.11 | 0.02 | enet | 17 | 0.02 | 2.1e-02 | 4.7 | 5.4 | 5.7e-08 | 0.73 | 0.02 | 0.79 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | EFR3B | 0.07 | 0.03 | bslmm | 348 | 0.03 | 3.5e-05 | -3.9 | 5.7 | 1.4e-08 | 0.34 | 0.07 | 0.43 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ADCY3 | 0.09 | 0.02 | enet | 11 | 0.04 | 3.2e-05 | 4.7 | -5.3 | 9.0e-08 | -0.79 | 0.00 | 0.89 | TRUE |