[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr3:26,563,909-28,211,713

Best TWAS P=2.97e-16 · Best GWAS P=1.57e-17 conditioned to 0.0107

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Aorta	SLC4A7	0.10	0.08	enet	15	0.08	5.4e-05	8.5	8.2	3.0e-16	0.92	0.00	0.99	TRUE
4	GTEx	Cells Transformed fibroblasts	SLC4A7	0.15	0.02	enet	21	0.04	4.0e-04	8.5	7.4	1.8e-13	0.80	0.00	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	NEK10	0.04	0.03	blup	450	0.03	9.5e-05	-5.4	6.9	6.5e-12	0.57	0.60	0.15	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	NEK10	0.02	0.02	lasso	4	0.02	1.3e-05	5.4	-5.5	3.6e-08	-0.69	0.60	0.36	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC4A7	0.09	0.00	enet	27	0.04	2.9e-05	-7.2	5.4	6.3e-08	0.40	0.09	0.59	FALSE