TWAS
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Traits
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Vascular/heart problems diagnosed by doctor
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chr4:80,488,345-82,578,407
Best TWAS P=7.87e-18 · Best GWAS P=2.51e-58 conditioned to 1.84e-42
80.5M
81M
81.5M
82M
82.5M
0
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physical position
-log10 P
Marginal
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Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
C4orf22
0.09
0.08
lasso
5
0.07
4.5e-09
-8
-8.6
7.9e-18
0.59
1.00
0.00
TRUE
2
CommonMind
Brain Pre-frontal Cortex
FGF5
0.07
0.06
lasso
2
0.05
5.4e-07
-8
-7.6
3.6e-14
0.53
0.76
0.14
FALSE