TWAS hub - C4orf22

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0940	0.0350	0.00180	0.081	0.031	0.049	0.063	0.072	4.0e-10	0.00010	1.3e-06	4.2e-08	4.5e-09
2	TCGA	Lung Adenocarcinoma	0.0305	0.0138	0.00019	0.023	0.023	0.013	NA	0.014	9.3e-04	0.00083	9.0e-03	NA	8.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hair/balding pattern: Pattern 4	35.6	86.2	170.0	13.0	-1.6
Hair/balding pattern: Pattern 2	19.6	24.9	49.3	-7.0	-0.8
Hair/balding pattern: Pattern 3	19.4	28.8	55.8	7.5	-1.4
Systolic Blood Pressure	18.0	90.0	174.2	13.2	-2.4
Cardiovascular Disease	15.2	50.2	100.4	10.0	0.2
Hypertension (Self-reported)	15.2	42.1	84.1	9.2	-0.4
High blood pressure	15.1	42.2	84.3	9.2	-0.4
Vascular/heart problems diagnosed by doctor	13.6	37.0	74.0	-8.6	-0.3
Systolic blood pressure, automated reading	12.3	35.9	70.7	8.4	-1.0
Medication: Blood pressure	9.7	18.5	36.7	6.1	-0.6
Illnesses of father: High blood pressure	9.1	11.3	22.2	4.7	-0.7
Medication: Blood pressure	9.0	15.9	31.5	5.6	0.6
Medication for cholesterol	7.3	11.0	20.1	-4.5	-1.4
Relative age of first facial hair	7.1	14.6	27.2	-5.2	1.4
Medication: Atenolol	6.9	8.6	16.2	4.0	1.0
Diastolic blood pressure, automated reading	6.5	20.1	40.1	6.3	-0.4
High blood pressure (mother)	6.0	8.3	16.6	4.1	-0.3
Medication for cholesterol, blood pressure or diabetes	5.7	9.4	18.8	-4.3	-0.0
Medication: Lisinopril	5.3	6.9	13.5	3.7	0.6
Osteoarthritis (self-reported)	4.7	6.1	11.3	-1.0	3.4
High blood pressure (siblings)	4.5	6.4	12.7	3.6	-0.4
Pulse rate, automated reading	4.4	14.2	16.9	-4.1	3.4
Alcohol drinker status: Never	3.8	4.6	4.7	-2.1	2.2
Peak expiratory flow (PEF)	3.7	8.6	15.3	1.4	-3.9
Hair Pigment	3.4	97.8	141.6	11.9	-7.3
Worrier / anxious feelings	3.3	6.2	8.1	2.1	2.8
Hearing aid user	3.3	3.8	5.4	-2.3	1.5
Ever used hormone-replacement therapy (HRT)	3.2	4.0	7.8	-0.5	2.8
Alcohol drinker status: Previous	3.2	3.6	7.0	-2.6	0.5
Supplements: Glucosamine	3.1	4.1	8.1	-0.2	2.8
Illnesses of father: None of the above (group 1)	3.1	3.9	7.5	-2.7	-0.5
Cholesterol lowering medication	3.1	4.6	7.6	2.8	1.2
Heart attack/myocardial infarction (self-reported)	3.1	4.0	4.4	1.9	2.1
Medication: Simvastatin	3.0	4.4	8.1	2.8	0.9
Number of operations (self-reported)	2.9	4.4	6.2	-1.6	2.5
Number of self-reported non-cancer illnesses	2.8	4.9	8.4	2.9	1.2
BMI	2.7	15.6	20.5	-4.5	3.3
Arm fat percentage (left)	2.7	10.8	11.9	-3.5	3.1
Medication: Bendroflumethiazide	2.7	4.0	7.3	2.7	0.9
Heart attack	2.6	3.3	3.7	1.7	1.9
Falls in the last year	2.6	3.5	5.7	-2.4	1.1
Pulse rate	2.6	4.4	5.5	-2.3	1.8
Mouth/teeth dental problems: Dentures	2.6	4.4	8.5	-0.6	2.9
Exposure to tobacco smoke outside home	2.6	3.4	6.6	-2.6	-0.5
Had major operations	2.6	3.1	6.0	-0.3	2.5
Reaction Time	2.5	4.7	7.5	-2.7	-1.4
Mouth/teeth dental problems	2.5	3.8	7.6	0.0	-2.8
Illnesses of siblings	2.5	3.6	7.0	-2.6	-0.4
Arm fat percentage (right)	2.5	9.9	10.7	-3.3	3.0
Body fat percentage	2.5	10.1	13.8	-3.7	2.5
Suffer from ‘nerves’	2.5	3.9	5.7	1.5	2.4
Medication: Aspirin	2.4	3.1	3.6	1.9	1.6
High cholesterol (Self-reported)	2.3	4.0	7.8	2.8	0.4
Ovarian Cancer	2.2	2.9	3.6	1.9	-1.5
Number of children fathered	2.2	2.5	3.9	2.0	-1.0
Leg fat percentage (left)	2.2	8.0	11.4	-3.4	2.1
Ever had prostate specific antigen (PSA) test	2.2	2.6	4.9	-0.5	-2.2
Medication: Omeprazole (e.g. Zanprol)	2.2	2.6	3.5	-1.3	1.9
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	4.6	-2.1	0.1
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	4.7	-0.5	2.2
Illnesses of mother	2.1	2.6	4.9	-2.2	-0.5
Leg fat percentage (right)	2.1	7.8	11.8	-3.4	1.9
Knee pain experienced in last month	2.1	3.2	5.9	-0.7	2.4
Trunk fat percentage	2.0	7.9	10.6	-3.3	2.3
Body mass index (BMI)	2.0	8.7	9.1	-2.9	3.0
Forced expiratory volume in 1-second (FEV1)	2.0	6.9	11.8	1.4	-3.4
Depression (self-reported)	2.0	2.4	3.4	1.2	-1.8
Medication: Omeprazole	2.0	2.4	2.6	-1.5	1.6
Lung cancer (father)	1.9	2.2	3.7	-1.9	0.9
Comparative height size at age 10	1.9	10.5	14.2	3.8	-2.6
Medication: Aspirin	1.9	2.5	3.2	1.3	1.8
Long-standing illness, disability or infirmity	1.9	2.9	2.9	-1.7	1.7
Mouth/teeth dental problems: Mouth ulcers	1.9	3.1	6.1	0.2	2.5
Neuroticism (Nagel 2018)	1.8	4.1	7.9	0.6	2.8
Worry (Nagel 2018)	1.8	3.9	6.1	1.3	2.5
Medication: Cholesterol lowering	1.8	2.8	5.5	2.3	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.1	-2.0	0.4
Unable to work because of sickness or disability	1.8	2.3	2.4	-1.5	1.5
HbA1C	1.7	1.9	3.7	0.0	1.9
Medication: Co-codamol	1.7	2.0	2.7	-1.1	1.6
Average weekly fortified wine intake	1.7	2.0	2.7	-1.1	1.7
Forced vital capacity (FVC)	1.7	6.6	12.2	1.0	-3.5
Financial difficulties in last 2 years	1.7	2.2	4.2	2.1	0.5
Breastfed as a baby	1.7	2.1	4.1	-0.4	2.0
Medication: Amlodipine	1.7	2.3	4.2	2.0	-0.7
Mean time to correctly identify matches	1.7	3.2	6.2	-2.5	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	3.0	-1.7	1.0
Alzheimer’s Disease (including proxy)	1.6	2.3	3.7	-0.9	1.9
Medication for hormone replacement therapy	1.6	1.8	3.6	-0.1	1.9
Leg fat mass (right)	1.6	6.2	9.2	-3.0	1.8
Supplements: Vitamin C	1.6	1.9	3.9	-2.0	0.1
Rheumatoid Arthritis	1.5	2.0	2.9	-1.1	-1.7
Medication: Ramipril	1.5	1.9	3.4	1.9	0.6
Exposure to tobacco smoke at home	1.5	1.6	2.0	-1.1	-1.4
Pulse wave reflection index	1.5	1.8	3.5	1.9	0.3
Medication: Seretide 50 evohaler	1.5	1.8	3.3	-1.8	-0.5
Whole body fat mass	1.5	6.3	8.9	-3.0	1.9
Risk taking	1.5	2.2	3.4	-1.0	-1.8
Leg fat mass (left)	1.5	6.0	9.0	-3.0	1.7
Sensitivity / hurt feelings	1.4	2.4	2.8	1.4	1.7
Diabetes (father)	1.4	1.7	3.1	-1.8	-0.6
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.1	1.0	1.5
Trunk fat mass	1.4	5.9	8.7	-3.0	1.8
Nervous feelings	1.4	2.7	5.2	2.3	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.6	8.6	0.8	-2.9
Forced vital capacity (FVC), Best measure	1.4	5.3	10.5	0.3	-3.2
Arm fat mass (left)	1.4	5.9	6.3	-2.4	2.5
Prostate Cancer	1.3	1.8	3.5	-1.9	-0.4
Hearing difficulty/problems: Yes	1.3	2.0	3.0	-0.9	-1.7
Alcohol intake versus 10 years previously	1.3	1.9	2.5	1.2	-1.6
Arm fat mass (right)	1.3	5.5	6.1	-2.5	2.2
Major Depression (MDD)	1.2	1.5	2.2	-1.5	0.9
Hypothyroidism (self reported)	1.2	2.8	3.1	-1.8	1.6
Lung FVC	1.2	6.0	11.5	-0.7	-3.4
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	3.6	-1.0	1.9
Number of full brothers	1.2	1.5	2.3	0.8	-1.5
Fractured/broken bones in last 5 years	1.2	1.6	3.1	-1.8	0.2
Bipolar Disorder (2018)	1.1	1.7	3.5	0.1	-1.9
Depression (Nagel 2018)	1.1	1.7	2.8	-1.7	0.8
Blood Red Count	1.1	10.5	19.6	4.4	1.2
Waist circumference	1.1	4.2	5.8	-2.4	1.6
Had menopause	1.1	1.3	1.5	1.1	1.2
Pain all over the body in last month	1.1	1.2	2.1	-0.5	1.5
Birth weight	1.1	2.3	2.7	1.7	-1.4
Worry too long after embarrassment	1.1	1.8	2.8	0.9	1.7
Mineral and other dietary supplements	1.1	1.4	2.8	-0.1	-1.7
Smoking status: Current	1.1	1.7	3.2	1.8	-0.4
Age started oral contraceptive pill	1.1	1.4	2.6	0.5	1.6
LDL Cholesterol	1.0	1.6	1.8	-1.2	1.3
Type 2 Diabetes (T2D) (2012)	1.0	1.1	1.7	1.3	-0.7
Medication: Metformin	1.0	1.5	2.9	-0.1	1.7
Had other major operations	1.0	1.2	2.4	-0.3	1.5
Father’s age at death	1.0	1.3	1.5	-1.2	-1.1
Tense / ‘highly strung’	1.0	1.6	1.8	1.3	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	2.2	1.5	-0.7
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.1	0.5	-1.4
Emphysema/chronic bronchitis	1.0	1.2	2.2	1.5	-0.4
Medication: Ibuprofen	1.0	1.1	1.8	-1.3	-0.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.3	2.3	0.5	1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.2	2.8	1.2	-1.7
Mother’s age at death	1.0	1.2	2.4	-1.6	-0.0
Pack years of smoking	1.0	1.5	2.5	-0.7	1.6
Neuroticism (2016)	0.9	1.3	2.6	-0.1	1.6
Hand grip strength (left)	0.9	2.5	4.6	2.1	-0.6
Supplements: Zinc	0.9	1.0	2.0	1.4	-0.1
Hand grip strength (right)	0.9	2.3	4.2	2.0	-0.7
Maternal smoking around birth	0.9	1.3	2.6	0.2	-1.6
Neuroticism score	0.9	1.9	2.1	1.3	1.5
Hip circumference	0.9	3.7	5.4	-2.3	1.4
Happiness	0.9	1.1	1.6	-1.3	0.7
Standing height	0.9	9.0	11.8	2.5	-3.4
Loud music exposure frequency	0.9	1.0	1.6	-1.3	0.6
Wheeze or whistling in the chest in last year	0.9	1.6	3.0	-1.7	-0.4
Eye problems/disorders: None of the above	0.9	1.0	2.0	0.3	-1.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	1.4	-1.0	1.2
Verbal and Numeric Reasoning (VNR)	0.8	1.8	3.4	0.5	1.8
Primary Biliary Cirrhosis	0.8	1.2	1.5	0.9	1.2
Severe depression (siblings)	0.8	0.9	1.9	-0.0	-1.4
Pack years adult smoking proportion	0.8	1.3	2.1	-0.6	1.5
Current tobacco smoking	0.8	1.3	2.4	1.5	-0.5
Taking other prescription medications	0.8	1.2	1.9	-0.7	1.4
Pulse wave Arterial Stiffness index	0.8	1.0	2.0	1.4	0.0
Glaucoma (self-reported)	0.8	0.9	1.7	1.3	-0.4
Ever had bowel cancer screening	0.8	1.0	1.8	-1.3	-0.4
Financial situation satisfaction	0.8	1.0	2.0	-0.4	1.4
Pain experienced in last month	0.8	1.3	1.8	1.4	-0.9
Heart disease (siblings)	0.8	1.0	1.8	1.4	0.5
Neuroticism	0.7	1.6	2.9	0.6	1.7
Average weekly spirits intake	0.7	0.8	1.6	-0.2	1.3
Impedance of leg (right)	0.7	3.4	5.7	1.0	-2.4
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	2.9	0.5	-1.7
Hearing difficulty/problems with background noise	0.7	1.1	2.0	-1.4	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.2	-1.1	-0.8
Heart disease (mother)	0.7	0.9	1.1	1.1	0.8
Number of full sisters	0.7	0.9	1.4	-0.6	-1.2
Leg pain on walking	0.7	0.9	1.0	-0.9	1.0
Smoking status: Previous	0.7	1.0	2.0	0.2	-1.4
Medication: Gliclazide	0.7	0.8	1.0	-1.0	-0.8
Guilty feelings	0.7	1.1	2.1	0.2	1.4
Eye problems/disorders: Glaucoma	0.7	0.8	1.4	1.2	0.5
Basal cell carcinoma (self-reported)	0.7	0.9	1.4	-0.6	-1.2
Bipolar Disorder (2011)	0.6	0.5	0.7	0.6	-0.8
Body Mass Index (BMI) (2010)	0.6	0.8	1.6	0.2	1.3
Mean Putamen Volume	0.6	0.6	0.9	-0.6	0.9
Chronotype (morning person)	0.6	1.3	2.1	0.7	1.5
Number of treatments/medications taken	0.6	1.1	1.5	0.8	1.2
Angina	0.6	0.8	1.4	1.2	0.5
Vitamin and mineral supplements	0.6	0.9	1.3	0.6	1.2
Medication: Levothyroxine sodium	0.6	1.0	1.8	-0.5	1.3
Impedance of leg (left)	0.6	2.8	4.7	0.9	-2.2
Angina (self-reported)	0.6	0.8	1.7	1.3	0.0
Commuting to job workplace: Walk	0.6	0.7	0.9	0.6	1.0
Medication: Paracetamol	0.6	0.9	1.7	-0.4	-1.3
Myopia	0.6	0.9	1.8	0.1	1.3
Bipolar Disorder or Schizophrenia	0.5	1.3	2.0	0.8	-1.4
Ulcerative Colitis (UC)	0.5	1.0	1.6	-0.7	1.3
Lupus	0.5	0.7	1.2	0.6	-1.1
Schizophrenia (2014)	0.5	1.1	1.5	1.2	-0.9
Ulcerative Colitis	0.5	0.7	1.0	-1.0	0.6
Heel T-Score	0.5	4.3	6.5	-1.5	-2.5
Smoking Status	0.5	1.1	1.3	1.1	-1.0
Diabetes (mother)	0.5	0.6	1.2	1.1	0.3
Qualifications: CSEs or equivalent	0.5	0.6	1.3	1.1	-0.0
Serious illness, injury or assault to yourself	0.5	0.6	1.1	-0.4	-1.1
Number of incorrect matches in round	0.5	0.8	0.9	-1.0	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	1.9	-0.6	-1.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.1	-0.3	1.1
Weight	0.5	2.6	3.5	-1.9	1.3
Prospective memory result	0.5	0.6	1.2	1.1	-0.1
Birth weight of first child	0.5	0.9	1.5	-1.2	0.6
Comparative body size at age 10	0.5	1.5	2.4	-1.6	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.2	1.1	-0.1
Age at first live birth	0.5	0.9	1.1	-1.1	-0.8
Pulse wave peak to peak time	0.5	0.6	1.1	-1.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.9	0.6	0.9
Illnesses of father: Heart disease	0.5	0.8	1.5	-0.0	1.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.0	-0.5	1.0
Miserableness	0.5	0.9	1.3	1.1	-0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.1	-1.1	0.2
Depressed Affect (Nagel 2018)	0.4	0.9	1.8	-0.1	1.3
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.4	1.2	-0.0
Past tobacco smoking	0.4	0.7	1.0	-0.7	1.0
Noisy workplace	0.4	0.5	0.8	-0.5	0.9
Asthma	0.4	0.8	1.5	1.2	0.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.1	1.1	-0.3
Blood clot in the leg (DVT)	0.4	0.5	0.9	-0.3	-0.9
Headache pain in last month	0.4	0.8	1.0	-1.0	0.7
Eye problems/disorders: Cataract	0.4	0.4	0.8	-0.1	0.9
Osteoporosis (self-reported)	0.4	0.6	0.9	-1.0	0.4
Average weekly beer plus cider intake	0.4	0.5	1.0	1.0	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.1	-0.1	-1.1
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.0	-0.3	1.4
Crohns Disease (2017)	0.3	0.5	0.7	0.8	0.7
Irritable Bowel Disease (IBD)	0.3	0.8	1.5	0.4	1.2
Blood White Count	0.3	1.9	2.6	1.1	1.6
Height	0.3	5.0	6.3	2.5	-1.9
Respiratory disease	0.3	0.6	1.1	1.1	-0.1
Tanning	0.3	4.1	7.6	-0.8	-2.8
Relative age voice broke	0.3	0.5	0.9	-1.0	-0.2
Chronic bronchitis/emphysema (father)	0.3	0.3	0.6	0.8	-0.2
Alcohol usually taken with meals	0.3	0.4	0.5	-0.6	-0.7
Qualifications: None of the above	0.3	0.6	0.8	-0.7	-0.9
Allergy	0.3	0.7	1.1	-1.1	-0.4
Time employed in main current job	0.3	0.4	0.5	0.7	0.5
Medication: Paracetamol	0.3	0.5	0.9	-0.3	-0.9
Alcohol intake frequency.	0.3	0.6	0.7	-0.7	0.9
Overall health rating	0.3	0.6	1.2	-1.1	-0.1
Friendships satisfaction	0.3	0.4	0.8	-0.9	-0.1
Asthma (self-reported)	0.3	0.6	1.2	1.1	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.6	-0.8	-0.2
Commuting to job workplace: Public transport	0.3	0.3	0.5	0.7	-0.2
Schizophrenia (2018)	0.2	0.5	0.8	0.9	-0.3
Alzheimer’s Disease (in father)	0.2	0.2	0.4	-0.0	0.6
Breast Cancer	0.2	0.5	0.9	0.2	-1.0
HDL Cholesterol	0.2	0.3	0.5	0.7	0.2
Lung FEV1/FVC ratio	0.2	0.8	0.8	0.9	-0.9
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.4	-0.6	-0.4
Ever had hysterectomy (womb removed)	0.2	0.2	0.3	-0.6	0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.4	0.4	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	0.8	0.3	0.9
Sitting height	0.2	1.5	2.7	-0.5	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.5	-0.1	0.7
Fluid intelligence score	0.2	0.4	0.6	-0.3	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	-0.2	0.6
Length of working week for main job	0.2	0.3	0.5	-0.2	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.3	-0.6	0.3
Gout (self-reported)	0.2	0.2	0.4	-0.6	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.4	-0.0	-0.6
Neck or shoulder pain in last month	0.2	0.2	0.4	-0.6	0.2
Migraine (self-reported)	0.2	0.2	0.2	-0.5	0.5
Age at last live birth	0.2	0.3	0.5	-0.2	-0.7
Average weekly red wine intake	0.2	0.2	0.4	0.1	-0.7
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.2	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.5	0.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.5	-0.4	-0.7
Average weekly champagne plus white wine intake	0.2	0.2	0.3	-0.6	-0.4
Irritability	0.2	0.3	0.3	0.5	0.6
Ever depressed for a whole week	0.2	0.2	0.4	-0.1	0.6
Supplements: Calcium	0.2	0.2	0.3	-0.5	-0.3
Impedance of whole body	0.2	0.9	1.5	0.5	-1.2
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	0.4	0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	0.1	0.4
Age at First Birth	0.1	0.1	0.1	0.2	-0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.3	0.5	-0.1
Fasting Glucose	0.1	0.2	0.2	-0.4	0.4
Blood Eosinophil Count	0.1	0.4	0.8	-0.3	0.9
Waist Hip Ratio (WHR)	0.1	0.3	0.5	0.7	-0.3
Allergy or Eczema	0.1	0.2	0.4	0.6	0.0
Leg fat-free mass (left)	0.1	0.6	0.9	-1.0	0.5
Townsend deprivation index at recruitment	0.1	0.1	0.1	0.2	-0.3
Fed-up feelings	0.1	0.2	0.2	0.4	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.5	0.1
Multivitamins +/- minerals	0.1	0.1	0.2	0.1	-0.5
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.2	0.3
Leg predicted mass (left)	0.1	0.6	0.9	-0.9	0.5
Diabetes (self-reported)	0.1	0.2	0.4	0.6	-0.0
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.4	0.6	-0.1
Impedance of arm (right)	0.1	0.4	0.7	0.4	-0.8
Trunk fat-free mass	0.1	0.8	1.1	0.7	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.2	-0.4	0.0
Medication: Lansoprazole	0.1	0.1	0.1	0.4	-0.1
Trunk predicted mass	0.1	0.7	1.0	0.7	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.3	0.4	0.5
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.3	0.5	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.3	0.1	-0.6
Health satisfaction	0.1	0.1	0.1	-0.3	-0.3
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	0.0	-0.5
Medication: Allopurinol	0.1	0.2	0.2	-0.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.1	-0.3	0.3
Chest pain or discomfort	0.1	0.2	0.4	-0.6	0.0
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	-0.3	0.3
Illnesses of siblings: Diabetes	0.1	0.1	0.2	-0.5	-0.3
Leg fat-free mass (right)	0.1	0.6	0.7	-0.9	0.7
Qualifications: nursing, teaching	0.1	0.1	0.3	0.5	-0.1
Back pain experienced in last month	0.1	0.2	0.3	-0.1	-0.5
Breast cancer (self-reported)	0.1	0.1	0.1	0.4	-0.1
Leg predicted mass (right)	0.1	0.6	0.6	-0.8	0.7
Wears glasses or contact lenses	0.1	0.2	0.2	0.5	-0.3
Ever taken oral contraceptive pill	0.1	0.1	0.3	-0.5	0.0
Medication: Atorvastatin	0.1	0.2	0.3	0.3	0.5
Commuting to job workplace: Cycle	0.1	0.2	0.3	-0.1	0.5
Crohns Disease (2012)	0.0	0.0	0.0	0.2	0.0
Triglycerides	0.0	0.0	0.0	-0.0	0.0
Blood Platelet Count	0.0	0.5	1.0	1.0	-0.0
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.0	-0.0
Age when periods started (menarche)	0.0	0.0	0.1	0.3	-0.1
Number of live births	0.0	0.1	0.1	-0.0	-0.3
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.1	0.4	-0.1
Impedance of arm (left)	0.0	0.1	0.2	-0.1	-0.4
Arm fat-free mass (right)	0.0	0.0	0.1	0.2	-0.1
Shortness of breath walking on level ground	0.0	0.1	0.1	0.1	-0.3
Qualifications: College or University degree	0.0	0.1	0.1	-0.3	0.2
Arm predicted mass (right)	0.0	0.0	0.0	-0.1	-0.0
Family relationship satisfaction	0.0	0.0	0.0	-0.1	0.2
Whole body fat-free mass	0.0	0.1	0.1	-0.1	-0.4
Mood swings	0.0	0.0	0.0	-0.1	0.1
Loneliness, isolation	0.0	0.0	0.0	0.0	-0.1
Whole body water mass	0.0	0.1	0.2	-0.0	-0.4
Ever smoked	0.0	0.1	0.1	0.4	0.1
Basal metabolic rate	0.0	0.1	0.3	-0.5	-0.0
Arm fat-free mass (left)	0.0	0.0	0.1	0.2	0.1
Arm predicted mass (left)	0.0	0.1	0.2	0.4	-0.2

Hub : Genes

C4orf22

Models

Trait associations