[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor :

chr6:42,586,058-44,034,691

Best TWAS P=1.87e-12 · Best GWAS P=8.68e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 NTR Blood ZNF318 0.04 0.03 lasso 8 0.02 1.3e-08 -6.4 -6.4 1.7e-10 0.83 0.49 0.51 FALSE
2 YFS Blood ZNF318 0.10 0.08 lasso 5 0.10 5.6e-31 -6.7 5.4 7.5e-08 -0.86 0.04 0.96 FALSE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CRIP3 0.08 0.08 blup 34 0.07 1.0e-04 -5.9 -5.5 4.3e-08 0.67 0.11 0.78 FALSE
4 The Cancer Genome Atlas Lung Adenocarcinoma ZNF318 0.05 0.06 lasso 3 0.05 1.1e-06 -7.1 7.0 1.9e-12 -0.99 0.00 1.00 TRUE
5 The Cancer Genome Atlas Soft Tissue Sarcoma ZNF318 0.04 0.02 blup 48 0.04 2.2e-03 -5.9 -5.7 1.4e-08 0.69 0.04 0.14 FALSE