Best TWAS P=1.87e-12 · Best GWAS P=8.68e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | ZNF318 | 0.04 | 0.03 | lasso | 8 | 0.02 | 1.3e-08 | -6.4 | -6.4 | 1.7e-10 | 0.83 | 0.49 | 0.51 | FALSE |
| 2 | YFS | Blood | ZNF318 | 0.10 | 0.08 | lasso | 5 | 0.10 | 5.6e-31 | -6.7 | 5.4 | 7.5e-08 | -0.86 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CRIP3 | 0.08 | 0.08 | blup | 34 | 0.07 | 1.0e-04 | -5.9 | -5.5 | 4.3e-08 | 0.67 | 0.11 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF318 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.1e-06 | -7.1 | 7.0 | 1.9e-12 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZNF318 | 0.04 | 0.02 | blup | 48 | 0.04 | 2.2e-03 | -5.9 | -5.7 | 1.4e-08 | 0.69 | 0.04 | 0.14 | FALSE |