Best TWAS P=5.8e-08 · Best GWAS P=2.96e-10 conditioned to 2.22e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | RP4-605O3.4 | 0.11 | 0.00 | lasso | 3 | 0.00 | 0.1730 | -5.5 | -5.2 | 1.9e-07 | -0.15 | 0.10 | 0.40 | FALSE |
| 2 | GTEx | Prostate | CERS5 | 0.19 | 0.08 | lasso | 4 | 0.02 | 0.1250 | -5.5 | -5.2 | 2.1e-07 | -0.11 | 0.06 | 0.30 | FALSE |
| 3 | GTEx | Testis | CERS5 | 0.12 | 0.06 | lasso | 6 | 0.07 | 0.0004 | -5.5 | -5.4 | 5.8e-08 | -0.14 | 0.11 | 0.45 | TRUE |
| 4 | GTEx | Whole Blood | RP4-605O3.4 | 0.04 | 0.04 | lasso | 4 | 0.01 | 0.0146 | -5.5 | -5.2 | 1.5e-07 | -0.09 | 0.12 | 0.60 | FALSE |