Best TWAS P=1.43e-07 · Best GWAS P=1.1e-07 conditioned to 0.000116
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SENP1 | 0.05 | 0.02 | blup | 555 | 0.04 | 1.7e-05 | -5.1 | 5.3 | 1.4e-07 | -0.14 | 0.06 | 0.94 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | RP1-197B17.3 | 0.28 | 0.06 | enet | 35 | 0.10 | 3.6e-08 | 4.2 | 5.2 | 1.7e-07 | -0.15 | 0.39 | 0.41 | TRUE |
| 3 | GTEx | Thyroid | RP1-197B17.3 | 0.30 | 0.14 | lasso | 7 | 0.11 | 6.4e-09 | 4.2 | 5.2 | 2.1e-07 | -0.16 | 0.39 | 0.53 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF641 | 0.11 | 0.12 | enet | 10 | 0.12 | 5.2e-12 | -5.0 | -5.1 | 3.0e-07 | 0.04 | 0.00 | 0.99 | FALSE |