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Vascular/heart problems diagnosed by doctor
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chr12:47,407,397-49,195,124
Best TWAS P=1.43e-07 · Best GWAS P=1.1e-07 conditioned to 0.000116
47.4M
47.6M
47.8M
48M
48.2M
48.4M
48.6M
48.8M
49M
49.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
SENP1
0.05
0.02
blup
555
0.04
1.7e-05
-5.1
5.3
1.4e-07
-0.14
0.06
0.94
TRUE
2
GTEx
Cells Transformed fibroblasts
RP1-197B17.3
0.28
0.06
enet
35
0.10
3.6e-08
4.2
5.2
1.7e-07
-0.15
0.39
0.41
TRUE
3
GTEx
Thyroid
RP1-197B17.3
0.30
0.14
lasso
7
0.11
6.4e-09
4.2
5.2
2.1e-07
-0.16
0.39
0.53
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
ZNF641
0.11
0.12
enet
10
0.12
5.2e-12
-5.0
-5.1
3.0e-07
0.04
0.00
0.99
FALSE