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Vascular/heart problems diagnosed by doctor
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chr12:54,158,993-54,760,824
Best TWAS P=3.47e-09 · Best GWAS P=1.58e-09 conditioned to 0.0282
54.2M
54.3M
54.4M
54.5M
54.6M
54.7M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Uterine Corpus Endometrial Carcinoma
FLJ12825
0.15
0.02
lasso
5
0.06
8.9e-03
6.0
5.9
3.5e-09
0.80
0.01
0.72
TRUE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
HOXC8
0.03
0.05
enet
5
0.04
2.4e-05
6.0
-5.8
7.0e-09
-0.93
0.00
0.99
FALSE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
HOXC6
0.03
0.02
blup
50
0.03
3.9e-04
6.0
-5.6
2.0e-08
-0.81
0.00
0.97
FALSE
1
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
HOXC5
0.02
0.00
blup
51
0.01
2.4e-02
5.8
5.3
1.5e-07
0.76
0.01
0.72
FALSE