Best TWAS P=3.47e-09 · Best GWAS P=1.58e-09 conditioned to 0.0282
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXC5 | 0.02 | 0.00 | blup | 51 | 0.01 | 2.4e-02 | 5.8 | 5.3 | 1.5e-07 | 0.76 | 0.01 | 0.72 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC6 | 0.03 | 0.02 | blup | 50 | 0.03 | 3.9e-04 | 6.0 | -5.6 | 2.0e-08 | -0.81 | 0.00 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC8 | 0.03 | 0.05 | enet | 5 | 0.04 | 2.4e-05 | 6.0 | -5.8 | 7.0e-09 | -0.93 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | FLJ12825 | 0.15 | 0.02 | lasso | 5 | 0.06 | 8.9e-03 | 6.0 | 5.9 | 3.5e-09 | 0.80 | 0.01 | 0.72 | TRUE |