[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr12:69,057,879-70,476,863

Best TWAS P=4.74e-10 · Best GWAS P=3.4e-09 conditioned to 0.271

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	YEATS4	0.25	0.12	enet	11	0.21	5.0e-12	-5.4	-6.2	4.7e-10	0.86	0.02	0.98	TRUE
7	GTEx	Pituitary	YEATS4	0.29	0.05	lasso	7	0.08	5.3e-03	-5.7	-6.1	8.4e-10	0.98	0.02	0.93	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	YEATS4	0.07	0.06	blup	73	0.06	4.2e-13	-5.3	-6.1	1.3e-09	0.93	0.05	0.95	FALSE
8	GTEx	Prostate	YEATS4	0.40	0.01	lasso	6	0.06	1.6e-02	-5.4	-5.6	1.7e-08	0.79	0.04	0.62	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	YEATS4	0.26	0.18	enet	17	0.29	4.9e-33	3.2	-5.6	1.9e-08	0.69	0.96	0.04	FALSE
5	GTEx	Cells Transformed fibroblasts	YEATS4	0.14	0.10	lasso	3	0.11	9.7e-09	-5.4	-5.4	5.1e-08	0.98	0.04	0.96	FALSE
14	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	YEATS4	0.20	0.21	lasso	1	0.19	7.2e-08	-5.4	-5.4	8.0e-08	0.99	0.03	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	YEATS4	0.37	0.23	lasso	7	0.45	4.6e-61	2.6	-5.3	9.0e-08	0.75	0.13	0.87	FALSE
4	GTEx	Brain Frontal Cortex BA9	YEATS4	0.28	0.00	lasso	4	0.08	4.1e-03	2.6	-5.3	9.2e-08	0.76	0.05	0.66	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	YEATS4	0.12	0.12	lasso	5	0.17	3.4e-10	2.6	-5.3	1.2e-07	0.73	0.08	0.91	FALSE
6	GTEx	Nerve Tibial	YEATS4	0.32	0.22	enet	15	0.32	2.6e-23	2.6	-5.3	1.3e-07	0.69	0.99	0.01	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	YEATS4	0.39	0.27	enet	12	0.47	1.2e-50	2.6	-5.2	1.8e-07	0.69	0.99	0.00	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	YEATS4	0.19	0.04	enet	15	0.08	4.2e-04	2.6	-5.1	2.8e-07	0.65	0.03	0.87	FALSE
3	GTEx	Brain Cerebellum	YEATS4	0.35	0.16	enet	34	0.20	1.5e-06	-2.9	-5.1	3.0e-07	0.63	0.11	0.69	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	YEATS4	0.24	0.14	lasso	7	0.26	1.8e-29	-5.4	-5.1	3.1e-07	0.77	0.07	0.93	FALSE