Best TWAS P=3.2e-13 · Best GWAS P=2.93e-22 conditioned to 4.83e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ATP2B1 | 0.08 | 0.01 | enet | 10 | 0.03 | 0.0035 | 8.3 | 7.3 | 3.2e-13 | 0.37 | 0.12 | 0.54 | TRUE |
| 2 | GTEx | Prostate | POC1B | 0.25 | 0.00 | enet | 37 | 0.01 | 0.1640 | 9.4 | -5.3 | 1.1e-07 | -0.54 | 0.03 | 0.58 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | LOC338758 | 0.14 | 0.00 | enet | 6 | 0.01 | 0.0619 | -1.6 | 5.6 | 1.8e-08 | 0.31 | 0.00 | 0.18 | FALSE |