Best TWAS P=4.12e-11 · Best GWAS P=7.84e-14 conditioned to 0.000288
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | KIAA1199 | 0.06 | 0.04 | bslmm | 581 | 0.03 | 2.1e-04 | 4.6 | -5.2 | 1.6e-07 | 0.58 | 0.12 | 0.73 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | -6.5 | 6.2 | 4.7e-10 | -0.83 | 0.16 | 0.82 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | 5.5 | 6.6 | 4.1e-11 | -0.81 | 0.04 | 0.49 | TRUE |