Best TWAS P=3.85e-08 · Best GWAS P=1.95e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SLC5A11 | 0.27 | 0.24 | lasso | 6 | 0.24 | 4.5e-12 | 5.1 | 5.3 | 1.0e-07 | 0.97 | 0 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | SLC5A11 | 0.14 | 0.02 | blup | 62 | 0.07 | 1.4e-05 | 5.1 | 5.4 | 7.4e-08 | 0.71 | 0 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SLC5A11 | 0.30 | 0.33 | lasso | 2 | 0.32 | 2.8e-14 | 5.2 | 5.5 | 3.9e-08 | 0.98 | 0 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC5A11 | 0.17 | 0.21 | lasso | 3 | 0.18 | 4.9e-11 | 5.2 | 5.2 | 2.2e-07 | 1.00 | 0 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC5A11 | 0.35 | 0.44 | lasso | 4 | 0.44 | 4.2e-47 | 5.1 | 5.2 | 2.5e-07 | 0.99 | 0 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | SLC5A11 | 0.24 | 0.15 | lasso | 3 | 0.14 | 1.1e-04 | 5.1 | 5.1 | 3.1e-07 | 0.97 | 0 | 0.96 | FALSE |