[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr16:3,025,993-5,441,125

Best TWAS P=2.99e-11 · Best GWAS P=1.1e-08 conditioned to 1.28e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Heart Left Ventricle	MGRN1	0.32	0.10	enet	18	0.33	3.6e-18	-4.2	-6.6	3.0e-11	-0.20	0.76	0.18	TRUE
6	GTEx	Skin Not Sun Exposed Suprapubic	AC006111.1	0.19	0.12	enet	13	0.18	2.1e-10	2.7	-5.4	7.9e-08	0.02	0.10	0.88	TRUE
2	GTEx	Brain Cortex	AC006111.1	0.32	0.02	enet	16	0.00	3.2e-01	3.5	-5.4	8.4e-08	-0.04	0.04	0.10	TRUE
5	GTEx	Muscle Skeletal	MGRN1	0.16	0.06	lasso	7	0.15	1.1e-14	-4.4	-6.3	2.6e-10	-0.18	0.53	0.43	FALSE
7	METSIM	Adipose	NUDT16L1	0.06	0.03	bslmm	392	0.04	2.2e-06	3.6	6.0	2.6e-09	0.33	0.39	0.58	FALSE
3	GTEx	Heart Atrial Appendage	MGRN1	0.33	0.30	enet	13	0.32	7.1e-15	3.7	-5.5	3.3e-08	-0.19	0.86	0.08	FALSE
1	GTEx	Adipose Visceral Omentum	AC006111.1	0.18	0.12	enet	12	0.10	1.1e-05	-3.6	-5.4	8.7e-08	0.02	0.58	0.07	FALSE
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NAT15	0.04	0.01	blup	56	0.04	4.2e-05	-4.8	5.3	1.1e-07	-0.05	0.03	0.90	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	NAT15	0.10	0.05	lasso	6	0.07	6.1e-07	-5.4	5.3	1.2e-07	-0.04	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	NAT15	0.06	0.04	blup	56	0.04	4.1e-05	-4.6	5.2	2.3e-07	-0.01	0.12	0.70	FALSE