[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr1:112,312,154-113,941,737

Best TWAS P=2.95e-15 · Best GWAS P=4.14e-17 conditioned to 7.87e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Thyroid Carcinoma	RHOC	0.04	0.03	enet	9	0.04	1.4e-04	7.2	7.9	2.9e-15	-0.30	0.00	0.98	TRUE
8	ROSMAP	Brain Pre-frontal Cortex	CAPZA1	0.05	0.06	lasso	3	0.06	1.1e-07	5.3	5.2	1.9e-07	-0.16	1.00	0.00	TRUE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	WNT2B	0.05	0.02	blup	46	0.05	4.7e-04	5.4	7.2	6.8e-13	-0.30	0.06	0.10	FALSE
5	GTEx	Muscle Skeletal	WNT2B	0.06	0.02	lasso	7	0.03	9.4e-04	5.5	6.7	2.6e-11	-0.14	0.56	0.02	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTTNBP2NL	0.04	0.00	blup	53	0.02	2.1e-03	5.8	6.0	2.4e-09	-0.27	0.03	0.19	FALSE
3	GTEx	Breast Mammary Tissue (Male)	WNT2B	0.18	0.07	lasso	6	0.05	2.3e-02	5.5	5.9	3.7e-09	-0.16	0.08	0.05	FALSE
1	GTEx	Adipose Subcutaneous	WNT2B	0.10	0.10	enet	19	0.06	1.2e-05	4.5	5.9	4.5e-09	-0.12	1.00	0.00	FALSE
2	GTEx	Artery Aorta	WNT2B	0.15	0.01	enet	7	0.01	1.0e-01	5.6	5.6	2.0e-08	-0.16	0.23	0.07	FALSE
4	GTEx	Breast Mammary Tissue (Female)	WNT2B	0.01	-0.01	enet	24	0.00	3.4e-01	-1.5	5.5	2.9e-08	-0.11	0.03	0.07	FALSE
7	GTEx	Skin Sun Exposed Lower leg	RHOC	0.07	0.02	lasso	3	0.02	1.5e-02	5.3	5.2	2.7e-07	-0.16	0.51	0.08	FALSE
6	GTEx	Nerve Tibial	RP4-671G15.2	0.07	0.06	lasso	2	0.06	2.9e-05	4.8	-5.1	2.9e-07	0.17	0.94	0.00	FALSE