Best TWAS P=2.84e-12 · Best GWAS P=5.66e-12 conditioned to 0.0898
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | CCBL2 | 0.31 | 0.18 | lasso | 5 | 0.23 | 1.7e-06 | -6.0 | 5.6 | 2.2e-08 | -0.85 | 0.04 | 0.94 | FALSE |
2 | GTEx | Pancreas | CCBL2 | 0.26 | 0.21 | lasso | 4 | 0.23 | 5.3e-10 | -6.0 | 5.4 | 7.1e-08 | -0.70 | 0.14 | 0.86 | FALSE |
3 | YFS | Blood | GTF2B | 0.01 | 0.00 | lasso | 3 | 0.01 | 2.3e-04 | -6.9 | -7.0 | 2.8e-12 | 0.86 | 0.01 | 0.98 | TRUE |