[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr17:46,258,510-48,139,500

Best TWAS P=1.17e-15 · Best GWAS P=1.75e-17 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	The Cancer Genome Atlas	Lung Adenocarcinoma	ZNF652	0.05	0.02	blup	55	0.02	2.5e-03	-7.9	8.0	1.2e-15	-0.79	0.04	0.87	TRUE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF652	0.03	0.03	enet	5	0.03	2.6e-04	-6.7	7.3	3.4e-13	-0.80	0.14	0.68	TRUE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF652	0.06	0.03	lasso	4	0.02	1.6e-03	-6.9	6.4	1.4e-10	-0.68	0.34	0.27	TRUE
5	GTEx	Cells Transformed fibroblasts	RP11-463M16.4	0.10	0.00	enet	21	0.01	2.8e-02	5.1	-6.4	1.7e-10	0.22	0.27	0.07	TRUE
3	GTEx	Artery Aorta	AC091133.1	0.10	0.07	lasso	5	0.07	1.2e-04	4.5	-6.0	2.6e-09	0.02	0.53	0.05	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	UBE2Z	0.16	0.01	enet	25	0.10	3.5e-04	4.3	5.7	1.4e-08	-0.09	0.28	0.04	TRUE
10	METSIM	Adipose	ZNF652	0.05	0.03	lasso	8	0.05	6.2e-08	3.5	5.2	1.9e-07	-0.63	0.91	0.09	TRUE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNF8	0.01	0.01	blup	47	0.01	9.1e-03	4.3	-5.2	2.5e-07	-0.10	0.06	0.22	TRUE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	ZNF652	0.09	0.01	enet	12	0.05	5.5e-04	-6.6	6.0	2.6e-09	-0.60	0.01	0.58	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	GNGT2	0.08	0.06	enet	7	0.08	3.9e-09	-4.8	-5.7	1.6e-08	0.59	0.89	0.10	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SNF8	0.08	0.07	lasso	5	0.08	9.3e-10	4.6	-5.6	1.9e-08	-0.09	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATP5G1	0.07	0.05	lasso	3	0.06	4.7e-08	5.6	-5.6	2.2e-08	-0.01	1.00	0.00	FALSE
6	GTEx	Esophagus Muscularis	SNF8	0.08	0.03	lasso	3	0.01	5.7e-02	5.3	-5.6	2.5e-08	-0.06	0.12	0.04	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNGT2	0.09	0.07	blup	48	0.06	2.7e-07	-4.8	-5.5	4.5e-08	0.63	0.17	0.83	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	UBE2Z	0.11	0.07	lasso	6	0.04	1.8e-03	5.3	-5.5	4.7e-08	-0.06	0.11	0.04	FALSE
8	GTEx	Muscle Skeletal	UBE2Z	0.06	0.02	lasso	8	0.03	9.8e-04	5.1	-5.4	8.1e-08	-0.08	0.78	0.01	FALSE
7	GTEx	Heart Left Ventricle	ATP5G1	0.24	0.22	lasso	4	0.22	9.3e-12	5.1	-5.3	1.4e-07	-0.03	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	SNF8	0.05	0.06	blup	47	0.06	1.0e-06	5.3	-5.2	2.1e-07	-0.09	0.14	0.86	FALSE