Best TWAS P=3.68e-11 · Best GWAS P=2.55e-18 conditioned to 6.3e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | PLCB1 | 0.06 | 0.01 | lasso | 3 | 0.03 | 7.8e-05 | -0.62 | -5.6 | 1.9e-08 | -0.69 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | PLCB1 | 0.23 | 0.09 | lasso | 9 | 0.09 | 1.7e-06 | 7.21 | -6.6 | 3.7e-11 | -0.55 | 0.66 | 0.21 | TRUE |