Best TWAS P=3.36e-09 · Best GWAS P=1.13e-09 conditioned to 1.91e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | TSPY26P | 0.08 | 0.01 | lasso | 4 | 0.03 | 1.7e-03 | 4.6 | 5.9 | 3.4e-09 | -0.10 | 0.28 | 0.09 | TRUE |
| 2 | GTEx | Artery Aorta | KIF3B | 0.15 | 0.00 | enet | 33 | 0.00 | 2.9e-01 | 3.1 | -5.8 | 7.0e-09 | 0.07 | 0.06 | 0.05 | FALSE |
| 3 | GTEx | Brain Cerebellum | TSPY26P | 0.25 | 0.06 | lasso | 6 | 0.15 | 2.9e-05 | -3.9 | 5.5 | 4.5e-08 | -0.09 | 0.12 | 0.09 | FALSE |
| 4 | GTEx | Thyroid | TSPY26P | 0.12 | 0.08 | enet | 18 | 0.08 | 7.2e-07 | 3.9 | 5.1 | 2.8e-07 | -0.19 | 0.84 | 0.07 | FALSE |
| 5 | NTR | Blood | C20orf160 | 0.01 | 0.00 | bslmm | 305 | 0.00 | 8.0e-03 | 4.3 | -5.8 | 7.0e-09 | 0.10 | 0.04 | 0.07 | TRUE |