TWAS
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Traits
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Traits
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Vascular/heart problems diagnosed by doctor
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chr20:29,927,166-31,615,615
Best TWAS P=3.36e-09 · Best GWAS P=1.13e-09 conditioned to 1.91e-07
30M
30.2M
30.4M
30.6M
30.8M
31M
31.2M
31.4M
31.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
TSPY26P
0.08
0.01
lasso
4
0.03
1.7e-03
4.6
5.9
3.4e-09
-0.10
0.28
0.09
TRUE
5
NTR
Blood
C20orf160
0.01
0.00
bslmm
305
0.00
8.0e-03
4.3
-5.8
7.0e-09
0.10
0.04
0.07
TRUE
2
GTEx
Artery Aorta
KIF3B
0.15
0.00
enet
33
0.00
2.9e-01
3.1
-5.8
7.0e-09
0.07
0.06
0.05
FALSE
3
GTEx
Brain Cerebellum
TSPY26P
0.25
0.06
lasso
6
0.15
2.9e-05
-3.9
5.5
4.5e-08
-0.09
0.12
0.09
FALSE
4
GTEx
Thyroid
TSPY26P
0.12
0.08
enet
18
0.08
7.2e-07
3.9
5.1
2.8e-07
-0.19
0.84
0.07
FALSE