[Hub]/) : Traits : Angina : →

chr1:109,098,737-110,517,617

Best TWAS P=3.27e-12 · Best GWAS P=3.28e-12 conditioned to 0.22

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CELSR2 0.03 0.00 lasso 10 0.01 1.5e-02 -5.1 5.7 1.2e-08 -0.58 0.10 0.33 FALSE
2 GTEx Esophagus Mucosa PSRC1 0.18 0.14 lasso 3 0.14 2.4e-09 -6.9 -6.8 1.2e-11 0.97 0.00 1.00 FALSE
3 GTEx Liver CELSR2 0.39 0.36 lasso 1 0.35 1.0e-10 -6.9 -6.9 6.8e-12 1.00 0.00 1.00 FALSE
4 GTEx Muscle Skeletal CELSR2 0.41 0.31 lasso 4 0.30 2.4e-30 -6.9 -6.7 2.0e-11 1.00 0.00 1.00 FALSE
5 GTEx Skin Sun Exposed Lower leg CELSR2 0.18 0.05 lasso 6 0.06 8.1e-06 -5.6 -5.7 1.1e-08 0.75 0.01 0.98 FALSE
6 GTEx Whole Blood PSRC1 0.14 0.04 lasso 3 0.03 6.9e-04 -7.0 -6.9 4.0e-12 0.99 0.00 1.00 FALSE
7 ROSMAP Brain Pre-frontal Cortex PSRC1 0.33 0.21 bslmm 430 0.26 1.2e-32 -6.9 -5.8 7.8e-09 0.82 0.00 1.00 FALSE
8 ROSMAP Brain Pre-frontal Cortex CELSR2 0.25 0.21 lasso 6 0.23 4.9e-29 -6.9 -6.7 2.1e-11 0.96 0.00 1.00 FALSE
9 YFS Blood PSRC1 0.25 0.18 enet 32 0.24 1.6e-76 -6.9 -5.8 5.3e-09 0.87 0.00 1.00 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma PSRC1 0.07 0.06 lasso 1 0.04 1.8e-03 -5.6 -5.6 1.7e-08 0.75 0.01 0.83 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSRC1 0.12 0.11 lasso 4 0.09 4.5e-06 -6.5 -6.4 1.4e-10 0.92 0.01 0.99 FALSE
12 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PSRC1 0.16 0.20 lasso 3 0.19 3.7e-09 -6.7 -6.7 2.9e-11 0.95 0.01 0.99 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SORT1 0.23 0.16 lasso 4 0.16 4.6e-08 -7.0 -7.0 3.3e-12 0.94 0.00 1.00 TRUE