[Hub]/) : Traits : Angina : →

chr1:109,098,737-110,517,617

Best TWAS P=3.27e-12 · Best GWAS P=3.28e-12 conditioned to 0.22

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SORT1	0.23	0.16	lasso	4	0.16	4.6e-08	-7.0	-7.0	3.3e-12	0.94	0.00	1.00	TRUE
6	GTEx	Whole Blood	PSRC1	0.14	0.04	lasso	3	0.03	6.9e-04	-7.0	-6.9	4.0e-12	0.99	0.00	1.00	FALSE
3	GTEx	Liver	CELSR2	0.39	0.36	lasso	1	0.35	1.0e-10	-6.9	-6.9	6.8e-12	1.00	0.00	1.00	FALSE
2	GTEx	Esophagus Mucosa	PSRC1	0.18	0.14	lasso	3	0.14	2.4e-09	-6.9	-6.8	1.2e-11	0.97	0.00	1.00	FALSE
4	GTEx	Muscle Skeletal	CELSR2	0.41	0.31	lasso	4	0.30	2.4e-30	-6.9	-6.7	2.0e-11	1.00	0.00	1.00	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	CELSR2	0.25	0.21	lasso	6	0.23	4.9e-29	-6.9	-6.7	2.1e-11	0.96	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSRC1	0.16	0.20	lasso	3	0.19	3.7e-09	-6.7	-6.7	2.9e-11	0.95	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSRC1	0.12	0.11	lasso	4	0.09	4.5e-06	-6.5	-6.4	1.4e-10	0.92	0.01	0.99	FALSE
9	YFS	Blood	PSRC1	0.25	0.18	enet	32	0.24	1.6e-76	-6.9	-5.8	5.3e-09	0.87	0.00	1.00	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	PSRC1	0.33	0.21	bslmm	430	0.26	1.2e-32	-6.9	-5.8	7.8e-09	0.82	0.00	1.00	FALSE
5	GTEx	Skin Sun Exposed Lower leg	CELSR2	0.18	0.05	lasso	6	0.06	8.1e-06	-5.6	-5.7	1.1e-08	0.75	0.01	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CELSR2	0.03	0.00	lasso	10	0.01	1.5e-02	-5.1	5.7	1.2e-08	-0.58	0.10	0.33	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	PSRC1	0.07	0.06	lasso	1	0.04	1.8e-03	-5.6	-5.6	1.7e-08	0.75	0.01	0.83	FALSE