[Hub]/) : Traits : High blood pressure :

chr19:16,462,417-18,007,950

Best TWAS P=1.52e-12 · Best GWAS P=1.73e-13 conditioned to 0.00217

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous HAUS8 0.11 0.09 lasso 3 0.08 5.4e-07 5.4 -5.4 7.5e-08 -0.62 0.32 0.68 FALSE
2 GTEx Artery Aorta HAUS8 0.18 0.12 lasso 2 0.09 7.3e-06 5.6 -5.6 2.5e-08 -0.63 0.35 0.60 FALSE
3 GTEx Artery Tibial HAUS8 0.16 0.02 lasso 7 0.02 4.7e-03 5.6 -6.3 2.8e-10 -0.62 0.22 0.70 FALSE
4 GTEx Artery Tibial CTD-3032J10.3 0.14 0.01 lasso 5 0.01 6.4e-02 7.4 -6.5 7.6e-11 -0.96 0.00 0.96 FALSE
5 GTEx Brain Cerebellar Hemisphere HAUS8 0.44 0.15 lasso 7 0.11 8.1e-04 5.4 -5.6 2.1e-08 -0.57 0.24 0.18 FALSE
6 GTEx Cells Transformed fibroblasts HAUS8 0.12 0.05 enet 19 0.05 1.0e-04 5.6 -6.6 4.0e-11 -0.53 0.60 0.21 FALSE
7 GTEx Esophagus Muscularis MYO9B 0.13 0.02 lasso 5 0.05 9.5e-04 4.7 -7.1 1.5e-12 -0.62 0.03 0.95 TRUE
8 GTEx Esophagus Muscularis HAUS8 0.20 0.11 lasso 4 0.09 5.1e-06 5.4 -5.1 3.0e-07 -0.59 0.67 0.16 FALSE
9 GTEx Muscle Skeletal HAUS8 0.15 0.10 lasso 4 0.08 1.6e-08 5.5 -5.9 3.8e-09 -0.62 0.99 0.01 FALSE
10 ROSMAP Brain Pre-frontal Cortex MYO9B 0.11 0.01 lasso 8 0.07 5.4e-09 6.8 -5.3 1.1e-07 -0.65 0.08 0.92 FALSE
11 ROSMAP Brain Pre-frontal Cortex HAUS8 0.05 0.05 enet 7 0.05 7.1e-07 5.5 -5.5 3.3e-08 -0.63 0.69 0.30 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma HAUS8 0.05 0.06 enet 12 0.06 2.9e-12 5.5 -5.9 3.2e-09 -0.57 1.00 0.00 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma HAUS8 0.12 0.06 lasso 5 0.06 1.8e-04 5.6 -5.3 1.1e-07 -0.58 0.40 0.30 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HAUS8 0.08 0.07 blup 55 0.07 6.7e-08 5.6 -5.5 4.7e-08 -0.53 0.99 0.01 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HAUS8 0.09 0.14 lasso 4 0.12 5.9e-14 5.4 -5.8 5.1e-09 -0.65 1.00 0.00 FALSE
16 The Cancer Genome Atlas Lung Adenocarcinoma HAUS8 0.04 0.04 lasso 2 0.03 1.6e-04 5.6 -5.2 1.6e-07 -0.57 0.56 0.05 FALSE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HAUS8 0.06 0.04 enet 4 0.05 3.9e-06 4.7 -5.4 5.4e-08 -0.54 0.91 0.01 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma HAUS8 0.20 0.13 lasso 2 0.11 2.4e-05 5.5 -5.3 1.0e-07 -0.61 0.46 0.12 FALSE
19 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HAUS8 0.21 0.11 enet 9 0.10 6.2e-05 -5.7 -7.0 2.3e-12 -0.56 0.10 0.47 TRUE
20 The Cancer Genome Atlas Prostate Adenocarcinoma HAUS8 0.13 0.10 blup 55 0.11 7.8e-12 5.6 -5.9 2.9e-09 -0.49 0.99 0.01 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma MYO9B 0.14 0.07 blup 103 0.10 5.0e-11 7.4 -5.6 2.5e-08 -0.59 0.00 1.00 FALSE
22 The Cancer Genome Atlas Stomach Adenocarcinoma HAUS8 0.06 0.04 blup 55 0.04 1.0e-03 5.4 -5.7 1.1e-08 -0.64 0.05 0.30 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma HAUS8 0.04 0.06 lasso 2 0.05 2.2e-05 5.5 -5.9 4.3e-09 -0.69 0.14 0.82 FALSE