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chr19:16,462,417-18,007,950

Best TWAS P=1.52e-12 · Best GWAS P=1.73e-13 conditioned to 0.00217

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Esophagus Muscularis	MYO9B	0.13	0.02	lasso	5	0.05	9.5e-04	4.7	-7.1	1.5e-12	-0.62	0.03	0.95	TRUE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	HAUS8	0.21	0.11	enet	9	0.10	6.2e-05	-5.7	-7.0	2.3e-12	-0.56	0.10	0.47	TRUE
6	GTEx	Cells Transformed fibroblasts	HAUS8	0.12	0.05	enet	19	0.05	1.0e-04	5.6	-6.6	4.0e-11	-0.53	0.60	0.21	FALSE
4	GTEx	Artery Tibial	CTD-3032J10.3	0.14	0.01	lasso	5	0.01	6.4e-02	7.4	-6.5	7.6e-11	-0.96	0.00	0.96	FALSE
3	GTEx	Artery Tibial	HAUS8	0.16	0.02	lasso	7	0.02	4.7e-03	5.6	-6.3	2.8e-10	-0.62	0.22	0.70	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	HAUS8	0.13	0.10	blup	55	0.11	7.8e-12	5.6	-5.9	2.9e-09	-0.49	0.99	0.01	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	HAUS8	0.05	0.06	enet	12	0.06	2.9e-12	5.5	-5.9	3.2e-09	-0.57	1.00	0.00	FALSE
9	GTEx	Muscle Skeletal	HAUS8	0.15	0.10	lasso	4	0.08	1.6e-08	5.5	-5.9	3.8e-09	-0.62	0.99	0.01	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	HAUS8	0.04	0.06	lasso	2	0.05	2.2e-05	5.5	-5.9	4.3e-09	-0.69	0.14	0.82	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HAUS8	0.09	0.14	lasso	4	0.12	5.9e-14	5.4	-5.8	5.1e-09	-0.65	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Stomach Adenocarcinoma	HAUS8	0.06	0.04	blup	55	0.04	1.0e-03	5.4	-5.7	1.1e-08	-0.64	0.05	0.30	FALSE
5	GTEx	Brain Cerebellar Hemisphere	HAUS8	0.44	0.15	lasso	7	0.11	8.1e-04	5.4	-5.6	2.1e-08	-0.57	0.24	0.18	FALSE
2	GTEx	Artery Aorta	HAUS8	0.18	0.12	lasso	2	0.09	7.3e-06	5.6	-5.6	2.5e-08	-0.63	0.35	0.60	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	MYO9B	0.14	0.07	blup	103	0.10	5.0e-11	7.4	-5.6	2.5e-08	-0.59	0.00	1.00	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	HAUS8	0.05	0.05	enet	7	0.05	7.1e-07	5.5	-5.5	3.3e-08	-0.63	0.69	0.30	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HAUS8	0.08	0.07	blup	55	0.07	6.7e-08	5.6	-5.5	4.7e-08	-0.53	0.99	0.01	FALSE
17	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	HAUS8	0.06	0.04	enet	4	0.05	3.9e-06	4.7	-5.4	5.4e-08	-0.54	0.91	0.01	FALSE
1	GTEx	Adipose Subcutaneous	HAUS8	0.11	0.09	lasso	3	0.08	5.4e-07	5.4	-5.4	7.5e-08	-0.62	0.32	0.68	FALSE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HAUS8	0.20	0.13	lasso	2	0.11	2.4e-05	5.5	-5.3	1.0e-07	-0.61	0.46	0.12	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	MYO9B	0.11	0.01	lasso	8	0.07	5.4e-09	6.8	-5.3	1.1e-07	-0.65	0.08	0.92	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	HAUS8	0.12	0.06	lasso	5	0.06	1.8e-04	5.6	-5.3	1.1e-07	-0.58	0.40	0.30	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	HAUS8	0.04	0.04	lasso	2	0.03	1.6e-04	5.6	-5.2	1.6e-07	-0.57	0.56	0.05	FALSE
8	GTEx	Esophagus Muscularis	HAUS8	0.20	0.11	lasso	4	0.09	5.1e-06	5.4	-5.1	3.0e-07	-0.59	0.67	0.16	FALSE